The San Francisco 49ers punched their ticket to NFL playoffs with a record of 12-5 this season. However, with Seattle winning the NFC West at 14-3, the Niners will have to hit the road to face the defending champs in Philly in NFL Wild Card Weekend, as the third-seeded Philadelphia Eagles await Kyle Shanahan's team in the opening round of the postseason.
So, without further ado, let's get into the opening 49ers vs Eagles odds for the Wild Card Round.
49ers vs Eagles Odds
| 49ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+3.5 -110 | 46 -115o / -105u | +160 |
| Eagles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-3.5 -110 | 46 -115o / -105u | -190 |
NFL Wild Card odds as of Monday at 12:10 a.m. ET.
49ers vs Eagles Wild Card Preview
The 49ers had a chance to stay home for the entirety of the playoffs, but lost Saturday night, so now their next home game would likely need to come in the Super Bowl.
The path got much harder to get there, though – not that a tough path is anything new to this team.
San Francisco has been crushed by injuries all season, on both sides of the ball. The defense is missing its top two playmakers in Nick Bosa and Fred Warner, and is badly lacking talent across the unit.
The offense finally got healthy to end the season, but enters the playoffs with an injury watch to Brock Purdy (stinger) and Trent Williams (hamstring), probably the team’s two most important players.
San Francisco’s defense lacks punch, so the 49ers will likely need to win shootouts. The offense had been red hot before scoring just three against Seattle.
Can Kyle Shanahan pull the strings again and get back to yet another NFC Championship, or maybe finally finish the job?
The defending Super Bowl champs will have a chance to run back the crown, but this season has been anything but expected for Philadelphia.
The team piled up plenty of wins and repeated as division champs, but had a pair of multiple-game losing streaks and never really felt like itself.
The Eagles' offense has been a mess. Saquon Barkley and A.J. Brown are always capable of ripping off a big play, but the offense has struggled to find a rhythm all season, and Jalen Hurts has been poor at best.
The offensive line has seen a significant drop in play, too, though a healthy Lane Johnson should do wonders for the playoffs. Can the Eagles get back to their winning ways in the run game? It’s been mostly tepid this season.
Vic Fangio’s defense is back to Super Bowl form, though. With an elite pair of young corners and the usual depth on the defensive line, Philly’s defense is built to repeat – but is the offense ready for a run?
Philadelphia games over the second half of the season have been dreadful slogs, a race to 20 points in slow, defensive battles. Can that formula work four more times?
















