2021 U.S. Open Updated Odds: Louis Oosthuizen Favored Over Bryson DeChambeau & Rory McIlroy

Louis Oosthuizen has not yet won a major on U.S. soil, but he's the betting favorite to get it done at the U.S. Open on Sunday at Torrey Pines.

The South African is one of three players tied for the lead at 5-under par entering the fourth and final round of the U.S. Open. He's +300 to win his second career major, his first since the 2010 Open Championship.

Oosthuizen is tied on the leaderboard with Mackenzie Hughes and Russell Henley. Henley has led or had a share of the lead after all three rounds. Despite holding a share of the lead, Hughes (+900) and Henley (+600) are just fourth and fifth on the oddsboard at DraftKings.

If oddsmakers are correct, Oosthuizen's biggest challengers will be former major champions Rory McIlroy and Bryson DeChambeau, who each come in at +550.

DeChambeau is the defending U.S. Open champion and entered the day +2000 to win the tournament. A 3-under round shot him up the leaderboard in a tie for fourth.

McIlroy was 4-under on the day as he looks for his second U.S. Open championship (2011). He most recently won the Wells Fargo in May.

McIlroy and DeChambeau are both two shots back of the leaders at 3-under for the tournament. Behind them at 2-under are Scottie Scheffler, Jon Rahm and Matthew Wolff. Two other major winners are part of the group tied for ninth: Dustin Johnson, Collin Morikawa, Christiaan Bezuidenhout, Xander Schauffele and Kevin Streelman.

Odds to win 2021 U.S. Open

Odds via DraftKings

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