The postseason races are heating up, which adds plenty of intrigue to Wednesday's 15-game MLB slate. All 30 teams are in action, and there are several marquee matchups, including Yankees vs. Astros, on the schedule.
Our MLB betting experts and betting systems have combed through today's MLB odds and found the best bets on the board. They've already made their predictions, so continue reading for today's MLB best bets.
MLB Best Bets Today
The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 1:05 p.m. | |
  | 4:10 p.m. | |
  | 6:45 p.m. | |
  | 8:10 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Tony Sartori's Mets vs Tigers Best Bet
By Tony Sartori
It’s worth taking a shot on Detroit in this matchup. The starting pitching edge goes to the Tigers, and the hitting disparity is minimal as both teams rank in the top 10 in runs scored per game, batting average, slugging percentage and OPS.
That leaves the bullpen as New York’s lone advantage in this contest. However, Detroit’s relief corps also ranks in the top half of the league in ERA, leaving the biggest margin in this matchup between Mize and Holmes.
The Tigers have also been dominant at Comerica Park this year, while the Mets are well below .500 on the road.
Pick: Tigers Moneyline (-105)
| | | |
Bet Labs' Orioles vs Padres Best Bet: Under Showing Value
By Bet Labs
Our "Steam Unders with Low O/U Support" system is built on the premise that sharp money moving totals downward, paired with weak public support on the under, creates an exploitable edge in the betting market.
The strategy focuses on regular-season games from 2019 to 2025 in which the closing total lands between 8 and 10 — sweet spots for scoring volatility. It isolates games in which the over/under line has dropped significantly from open to close, signaling smart money on the under, yet public sentiment heavily favors the over, with only a small share of bets backing the under. This mismatch between money and ticket count indicates potential value, especially when the difference between those two figures is meaningful but not extreme. To reduce noise, the system excludes games played in extreme heat or cold, only including those where temperatures range from mild to warm. It also requires both teams to have a recent record of games that hover around the total, suggesting no extreme streaks skewing expectations. These filters ensure that neither team is riding unsustainable over or under trends.
Ultimately, this system looks for low-confidence unders that have been steamed down by sharp bettors, where public interest is light and the number still sits within a realistic scoring range. The result is a consistent edge, backed by a high sample size and strong return on investment.
Overall, this system is 558-389-47 (59%) and has generated a 14% ROI. This season, the system has generated an 11% ROI and has cashed 58% of its picks (140-101-9).
