The Detroit Lions and Buffalo Bills will face off in NFL Week 2 on Thursday Night Football. Kickoff is scheduled for 8:15 p.m. ET at Highmark Stadium, and the game will be broadcast live on Amazon Prime Video.
For my Lions vs Bills anytime TD picks, I'm targeting Detroit tight end Sam LaPorta.
Continue below for my Lions vs Bills anytime touchdown preview for Thursday Night Football Week 2.
Lions vs Bills Anytime Touchdown Props
- Sam LaPorta Anytime Touchdown (+230; bet365)
Lions vs Bills Anytime Touchdown Scorer Picks
Sam LaPorta Anytime Touchdown (+230)

This is a great matchup for Sam LaPorta.
Although he only scored three touchdowns last year, he looked great in Week 1 and appears fully healthy. Even though he didn't reach the end zone against the Saints, he still logged eight targets — including two in the red zone.
Tonight, he faces a Bills defense that had trouble slowing down the Texans' passing game last week.
We know LaPorta is firmly established as the TE1 in this offense, and he ran the third-most routes among all Lions pass-catchers in Week 1.
With 20 career touchdowns over a 42-game sample size, his TD odds haven't been priced above +250 since his rookie season.
At +220, I’ll gladly bank on LaPorta finding the end zone for his first touchdown of the year.
Pick: Sam LaPorta Anytime Touchdown (+230)













