Panthers vs. Senators Odds & Betting Predictions - October 21, 2026
Panthers at Senators
11:30 pm • ESPN+Panthers at Senators Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Panthers 4-2-2 | N/A | N/A | N/A | |
Senators 6-2-0 | N/A | N/A | N/A | |

Canadian Tire CentreOttawa
Prop Odds Comparison
Line Movement Tracker
Panthers vs. Senators Public Betting Percentages
Betting Trends
- Senators are 5-0 in their last 5 games.
- Senators are 2-3 in their last 5 games against the spread
- Senators are 3-1 in their road games against the spread
- The totals have gone OVER in 0 of Senators' last 5 games
- The totals have gone OVER in 1 of Senators' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Senators vs. Panthers Injury Updates

Senators Injuries
- William EklundLW
Eklund is out with ankle
Out
- Nikolas MatinpaloD
Matinpalo is out with upper body
Out

Panthers Injuries
- Jacob MarkstromG
Markstrom is day-to-day with undisclosed
Day-to-Day
- Brad MarchandF
Marchand is out with leg
Out
- Radko GudasD
Gudas is day-to-day with undisclosed
Day-to-Day
- Aleksander BarkovC
Barkov is out with lower body
Out
- Jonah GadjovichLW
Gadjovich is out with upper body
Out
Team Stats
Panthers vs. Senators Odds Comparison
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Panthers at Senators Team Totals
MatchupOverUnder | ||
|---|---|---|
Panthers 4-2-2 | N/A | N/A |
Senators 6-2-0 | N/A | N/A |
