Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025

Sassuolo at Inter

6:45 pm

Sassuolo

1-3

1

1 - 2

Inter

2-2

2

MatchupOpenSpreadTotalMoneyline
Sassuolo 1-3	+1.5	+1.5-115	o3.5+125	N/A
Inter 2-2	u2.5	-1.5-125	u3.5-163	N/A

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Sunday 6:45 p.m.

September 21, 2025

Giuseppe MeazzaMilan

Serie A Public Betting

Inter are 2-2 in their last 5 games.
Inter are 1-3 in their last 5 games against the spread
Inter are 0-1 in their road games against the spread
The totals have gone OVER in 3 of Inter' last 4 games
The totals have gone OVER in 2 of Inter' 3 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Inter	1-3	1-2	0-1	1-2	N/A
Sassuolo	2-2	1-1	1-1	0-1	2-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Inter	3-1	2-1	1-0	2-1	N/A
Sassuolo	1-3	0-2	1-1	1-0	0-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Inter	2-2	2-1	0-1	2-1	N/A
Sassuolo	1-3	1-1	0-2	0-1	1-2

date	opponent	score	spread	over/under	moneyline
Sep 13th	@JUV	L 3-4	-0.5 L	O 2.5	-
Aug 31st	UDI	L 1-2	-1.5 L	O 2.5	-
Aug 25th	TOR	W 5-0	-1.5 W	O 2.5	INT -275
May 23rd	@COM	W 2-0	-0.5 W	U 3.5	INT -135
May 18th	LAZ	W 2-2	-1 L	O 2.5	LAZ -147

Nemanja Matic
MID
Calf/Shin Injury
Out Indefinitely
Armand Lauriente
F
Back Injury
Out
Yeferson Paz Blandon
DEF
Paz Blandon is out with muscle
Out

See more SERIEA Injuries

Sassuolo

Inter

8

Fouls

13

7

Shots

15

3

Corners

7

3

Offsides

2

0

Red Cards

0

1

Yellow Cards

2

5

Shots On Goal

5

40%

Possession Time

60%

Sassuolo

Goalkeeping

Inter

Could not load odds

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MatchupOverUnder
Sassuolo 1-3	o0.5-140	u0.5+105
Inter 2-2	o2.5+107	u2.5-152