Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025
Sassuolo at Inter
6:45 pm
Sassuolo
2-2-21
1 - 2

Inter
5-0-12
Sassuolo at Inter Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Sassuolo 2-2-2 | +1.5 | +1.5-115 | o3.5+125 | +825 |
Inter 5-0-1 | u2.5 | -1.5-125 | u3.5-163 | -325 |

Stadio Giuseppe MeazzaMilan
Line Movement Tracker
Sassuolo vs. Inter Public Betting Percentages
Sassuolo
Public
Inter
1%
Bets%
99%Money%
Betting Trends
- Inter are 0-1 in their last 5 games.
- Inter are 0-1 in their last 5 games against the spread
- Inter are 0-1 in their road games against the spread
- The totals have gone OVER in 0 of Inter' last 1 games
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 0-1 | N/A | 0-1 | N/A | 0-1 | |
| 5-1 | 3-0 | 2-1 | 1-1 | 4-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 0-1 | N/A | 0-1 | N/A | 0-1 | |
| 5-1 | 2-1 | 3-0 | 2-0 | 3-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 0-1 | N/A | 0-1 | N/A | 0-1 | |
| 2-2 | 2-0-1 | 0-2-1 | 1-1 | 1-1-2 |
Last 5 Matchups
Inter vs. Sassuolo Injury Updates

Inter Injuries
- Henrikh MkhitaryanMID
Back Injury
Out Indefinitely

Sassuolo Injuries
- Nemanja MaticMID
Calf/Shin Injury
Out Indefinitely
- Armand LaurienteF
Back Injury
Out
- Ismael KoneMID
Ismaël Koné is expected to return Early November 2026 from Broken ankle.
Out
Team Stats

Sassuolo
Inter

8
Fouls
13
7
Shots
15
3
Corners
7
3
Offsides
2
0
Red Cards
0
1
Yellow Cards
2
5
Shots On Goal
5
40%
Possession Time
60%

Sassuolo
Goalkeeping
Inter

Sassuolo vs. Inter Odds Comparison
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Sassuolo at Inter Team Totals
MatchupOverUnder | ||
|---|---|---|
Sassuolo 2-2-2 | N/A | N/A |
Inter 5-0-1 | N/A | N/A |
