| Ruben Loftus-Cheek | MID | Out | Heel Injury | Heel Injury | Jan 5 |
| Christian Pulisic | F | Out | Knock | Knock | Mar 4 |
| Mike Maignan | GK | Out | Suspended | Suspended | Aug 20 |
| Luka Modric | MID | Doubtful | None | Modric is doubtful | Dec 1 |
| Fikayo Tomori | DEF | Out | Knock | Knock | Jul 11 |
| Pervis Estupinan | DEF | Out | Hamstring | Hamstring | Apr 21 |
| Rafael Leao | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Oct 4 |
| Strahinja Pavlovic | DEF | Out indefinitely | Knock | Knock | Sep 20 |
| Ademola Lookman | F | Out indefinitely | Illness | Illness | Dec 27 |
| Sead Kolasinac | DEF | Out | Groin Strain | Groin Strain | Mar 31 |
| Raoul Bellanova | DEF | Doubtful | Raoul Bellanova is Doubtful with Hamstring Injury. | Bellanova is doubtful with hamstring | Jan 27 |
| Lazar Samardzic | MID | Out indefinitely | Knee Injury | Knee Injury | Feb 21 |
| Kamaldeen Sulemana | F | Out | Ankle/Foot Injury | Ankle/Foot Injury | Nov 14 |
| Charles De Ketelaere | F | Out | Charles De Ketelaere is expected to return Late October 2025 from Thigh injury. | De Ketelaere is out with thigh | Oct 9 |
| Odilon Kossounou | DEF | Out indefinitely | None | Kossounou is injured | Feb 13 |
| Bacary Sagna | DEF | Out indefinitely | Groin Strain | Groin Strain | May 1 |
| Cheick Tidiane Diabaté | A | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | Jun 17 |
| V. Behrami | MID | Out indefinitely | Hamstring | Hamstring | Apr 17 |
| M. Balotelli | A | Out indefinitely | Knock | Knock | May 27 |
| Andrea Belotti | F | Out | Andrea Belotti is expected to return Early April 2026 from Cruciate ligament injury. | Belotti is out with knee | Dec 5 |
| Yerry Mina | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Nov 14 |
| Michael Folorunsho | MID | Out | Michael Folorunsho is expected to return Early February 2026 from Leg injury. | Folorunsho is out with leg | Jan 19 |
| Alessandro Deiola | MID | Out | Alessandro Deiola is expected to return Early February 2026 from Thigh injury. | Deiola is out with thigh | Jan 19 |
| Alessandro Di Pardo | DEF | Out | Alessandro Di Pardo is expected to return Mid February 2026 from Ankle injury. | Di Pardo is out with ankle | Jan 23 |
| Alberto Moreno | DEF | Out | Suspended | Suspended | Feb 18 |
| Diego Carlos | DEF | Out indefinitely | None | Carlos is injured | Jan 23 |
| Alvaro Morata | F | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Alberto Cerri | F | Out indefinitely | None | Cerri is injured | May 22 |
| Edoardo Goldaniga | DEF | Doubtful | Edoardo Goldaniga is Doubtful with Heel injury. | Goldaniga is doubtful with heel | Dec 28 |
| Antonio Sanabria | F | Out | Suspended | Suspended | Feb 4 |
| Jeremy Sarmiento | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Apr 11 |
| Michele Collocolo | MID | Out indefinitely | Michele Collocolo is Unknown with Muscle injury. | Collocolo is injured with muscle | Jan 25 |
| B. Adekanye | A | Out indefinitely | Hamstring | Hamstring | Dec 30 |
| David De Gea | GK | Out indefinitely | Knock | Knock | Apr 5 |
| Moise Kean | F | Out | Suspended | Suspended | Sep 18 |
| Marin Pongracic | DEF | Out | Suspended | Suspended | Mar 6 |
| Abdelhamid Sabiri | MID | Out | Suspended | Suspended | Jun 16 |
| Manor Solomon | MID | Out | Knee Injury | Knee Injury | Jan 5 |
| Tariq Lamptey | DEF | Out indefinitely | Tariq Lamptey is Unknown with Knee injury. | Lamptey is injured with knee | Aug 26 |
| Oliver Christensen | GK | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Mar 6 |
| Fabiano Parisi | DEF | Out | Fabiano Parisi is expected to return Mid February 2026 from Thigh injury. | Parisi is out with thigh | Jan 22 |
| Maxwel Cornet | MID | Out | Calf/Shin Injury | Calf/Shin Injury | Mar 9 |
| Aaron Martin | DEF | Out indefinitely | Groin Strain | Groin Strain | Sep 19 |
| Benjamin Siegrist | GK | Out | Benjamin Siegrist is expected to return Early February 2026 from Broken finger. | Siegrist is out with finger | Jan 19 |
| Jean Akpa | MID | Out indefinitely | None | Akpa is injured | Feb 13 |
| Domagoj Bradaric | DEF | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Feb 5 |
| Enzo Ebosse | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Sep 9 |
| Amin Sarr | F | Out | Thigh Muscle Strain | Thigh Muscle Strain | Apr 11 |
| Armel Bella-Kotchap | DEF | Out | Shoulder Injury | Shoulder Injury | Apr 10 |
| Tomas Suslov | MID | Out | Tomas Suslov is expected to return Late February 2026 from Cruciate ligament injury. | Suslov is out with knee | Dec 5 |
| Daniel Mosquera | F | Doubtful | Daniel Mosquera is Doubtful with Physical discomfort. | Mosquera is doubtful with soreness | Jan 27 |
| Nicolas Valentini | DEF | Doubtful | Nicolás Valentini is Doubtful with Physical discomfort. | Valentini is doubtful with soreness | Jan 20 |
| Moatasem Al-Musrati | MID | Out indefinitely | None | Al-Musrati is injured | May 9 |
| Rafik Belghali | DEF | Doubtful | Rafik Belghali is Doubtful with Thigh injury. | Belghali is doubtful with thigh | Jan 16 |
| Henrikh Mkhitaryan | MID | Out indefinitely | Back Injury | Back Injury | Mar 31 |
| Yann Sommer | GK | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Dec 6 |
| Nicolo Barella | MID | Out | Nicolò Barella is expected to return Early February 2026 from Muscle injury. | Barella is out with muscle | Jan 27 |
| Tomas Palacios | DEF | Doubtful | Tomás Palacios is Doubtful with Muscle injury. | Palacios is doubtful with muscle | Dec 28 |
| Filip Kostic | F | Out indefinitely | Virus | Virus | Jan 24 |
| Daniele Rugani | DEF | Out | Daniele Rugani is expected to return Early February 2026 from Calf injury. | Rugani is out with calf | Dec 21 |
| Arkadiusz Milik | F | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Apr 22 |
| Teun Koopmeiners | MID | Out indefinitely | None | Koopmeiners is injured | Nov 2 |
| Pedro | F | Out indefinitely | Shoulder Injury | Shoulder Injury | Sep 28 |
| Patric | DEF | Out | Patric is expected to return Early February 2026 from Muscle injury. | Patric is out with muscle | Jan 19 |
| Samuel Gigot | DEF | Out | Ankle/Foot Injury | Ankle/Foot Injury | Mar 13 |
| Toma Basic | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 14 |
| Nicolo Rovella | MID | Doubtful | Nicolò Rovella is Doubtful with Muscle injury. | Rovella is doubtful with muscle | Jan 23 |
| Lassana Coulibaly | MID | Out | Suspended | Suspended | May 24 |
| Tete Morente | F | Out indefinitely | Toe Injury | Toe Injury | Feb 16 |
| Medon Berisha | F | Out | Medon Berisha is expected to return Early February 2026 from Knee injury. | Berisha is out with knee | Jan 19 |
| Pontus Almqvist | F | Out | Pontus Almqvist is expected to return Early February 2026 from Muscle injury. | Almqvist is out with muscle | Jan 19 |
| Zion Suzuki | GK | Out | Zion Suzuki is expected to return Early February 2026 from Broken hand. | Suzuki is out with hand | Jan 10 |
| Lautaro Valenti | DEF | Out | Lautaro Valenti is expected to return Mid February 2026 from Muscle injury. | Valenti is out with muscle | Jan 27 |
| Matija Frigan | F | Out | Matija Frigan is expected to return Early March 2026 from Cruciate ligament injury. | Frigan is out with knee | Dec 5 |
| Juan Cuadrado | DEF | Out | Juan Cuadrado is expected to return Mid February 2026 from Hamstring Injury. | Cuadrado is out with hamstring | Jan 27 |
| Mateus Lusuardi | DEF | Doubtful | Mateus Lusuardi is Doubtful with Physical discomfort. | Lusuardi is doubtful with soreness | Jan 2 |
| Isak Vural | MID | Out | Isak Vural is expected to return Mid February 2026 from Knee injury. | Vural is out with knee | Jan 19 |
| Arturo Calabresi | DEF | Suspended | Arturo Calabresi is serving a suspension for Yellow cards. | Calabresi is suspended with yellow cards | Jan 23 |
| Adrian Semper | GK | Out | Adrian Semper is expected to return Mid February 2026 from Knee injury. | Semper is out with knee | Jan 23 |
| A. Tripaldelli | DEF | Out indefinitely | Knock | Knock | Nov 25 |
| Romelu Lukaku | F | Out | Romelu Lukaku is expected to return Early November 2025 from Thigh injury. | Lukaku is out with thigh | Oct 20 |
| Frank Anguissa | MID | Out | Suspended | Suspended | Feb 8 |
| Matteo Politano | F | Out | Matteo Politano is expected to return Early February 2026 from Thigh injury. | Politano is out with thigh | Jan 19 |
| Stanislav Lobotka | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Dec 12 |
| Vanja Milinkovic-Savic | GK | Out | Vanja Milinković-Savić is expected to return Early February 2026 from Thigh injury. | Milinkovic-Savic is out with thigh | Jan 26 |
| Mathias Olivera | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 4 |
| Amir Rrahmani | DEF | Out | Amir Rrahmani is expected to return Early February 2026 from Muscle injury. | Rrahmani is out with muscle | Jan 18 |
| Eljif Elmas | MID | Out indefinitely | None | Elmas is injured | Jan 1 |
| Nemanja Matic | MID | Out indefinitely | Calf/Shin Injury | Calf/Shin Injury | Feb 21 |
| Armand Lauriente | F | Out | Back Injury | Back Injury | Nov 14 |
| Edoardo Pieragnolo | DEF | Doubtful | Edoardo Pieragnolo is Doubtful with Muscle injury. | Pieragnolo is doubtful with muscle | Dec 28 |
| Daniel Boloca | MID | Doubtful | Daniel Boloca is Doubtful with Muscle injury. | Boloca is doubtful with muscle | Dec 19 |
| Jeroen Zoet | GK | Out indefinitely | Knock | Knock | Oct 20 |
| Daniele Verde | MID | Out indefinitely | Hamstring | Hamstring | May 5 |
| Adam Masina | DEF | Out indefinitely | Knee Injury | Knee Injury | Dec 29 |
| Giovanni Simeone | F | Doubtful | Giovanni Pablo Simeone is Doubtful with Physical discomfort. | Simeone is doubtful with soreness | Jan 23 |
| Adrien Tameze | MID | Out | Back Injury | Back Injury | Oct 6 |
| Guillermo Maripan | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 13 |
| Perr Schuurs | DEF | Out indefinitely | Knee Injury | Knee Injury | Jul 19 |
| Ardian Ismajli | DEF | Out | Ardian Ismajli is expected to return Early February 2026 from Muscle injury. | Ismajli is out with muscle | Jan 24 |
| Gvidas Gineitis | MID | Out | Gvidas Gineitis is expected to return Early February 2026 from Thigh injury. | Gineitis is out with thigh | Jan 20 |
| Zannetos Savva | MID | Doubtful | Savva, Zannetos: doubtful - injured | Savva is doubtful | Aug 22 |
| Nicolo Zaniolo | MID | Out | Nicolò Zaniolo is expected to return Mid February 2026 from Knee injury. | Zaniolo is out with knee | Jan 20 |
| Kingsley Ehizibue | DEF | Out indefinitely | Concussion | Concussion | Apr 17 |
| Adam Buksa | F | Out | Ankle Ligaments | Ankle Ligaments | Apr 11 |
| Hassane Kamara | DEF | Out | Hassane Kamara is expected to return Early February 2026 from Muscle injury. | Kamara is out with muscle | Jan 27 |
Benevento Calcio
Brescia Calcio
FC Crotone
S.P.A.L. 2013
