| Ruben Loftus-Cheek | MID | Out | Heel Injury | Heel Injury | Jan 5 |
| Christian Pulisic | F | Out | Knock | Knock | Mar 4 |
| Mike Maignan | GK | Out | Suspended | Suspended | Aug 20 |
| Luka Modric | MID | Doubtful | None | Modric is doubtful | Dec 1 |
| Fikayo Tomori | DEF | Out | Knock | Knock | Jul 11 |
| Pervis Estupinan | DEF | Out | Hamstring | Hamstring | Apr 21 |
| Rafael Leao | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Oct 4 |
| Strahinja Pavlovic | DEF | Out indefinitely | Knock | Knock | Sep 20 |
| Sead Kolasinac | DEF | Out | Groin Strain | Groin Strain | Mar 31 |
| Francesco Rossi | GK | Doubtful | Francesco Rossi is Doubtful with Physical discomfort. | Rossi is doubtful with soreness | Apr 25 |
| Lazar Samardzic | MID | Out indefinitely | Knee Injury | Knee Injury | Feb 21 |
| Kamaldeen Sulemana | F | Out | Ankle/Foot Injury | Ankle/Foot Injury | Nov 14 |
| Odilon Kossounou | DEF | Out indefinitely | None | Kossounou is injured | Feb 13 |
| Lorenzo Bernasconi | DEF | Out | Lorenzo Bernasconi is expected to return Early May 2026 from Knee injury. | Bernasconi is out with knee | Apr 24 |
| Bacary Sagna | DEF | Out indefinitely | Groin Strain | Groin Strain | May 1 |
| Cheick Tidiane Diabaté | A | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | Jun 17 |
| Lukasz Skorupski | GK | Out | Lukasz Skorupski is expected to return Early May 2026 from Hamstring Injury. | Skorupski is out with hamstring | Apr 19 |
| Federico Bernardeschi | F | Out | Federico Bernardeschi is expected to return Early May 2026 from Thigh injury. | Bernardeschi is out with thigh | Apr 19 |
| Nicolo Casale | DEF | Out | Nicolò Casale is expected to return Early May 2026 from Ankle injury. | Casale is out with ankle | Apr 17 |
| Juan Miranda | DEF | Out indefinitely | Knock | Knock | Apr 11 |
| Joao Mario | DEF | Out | João Mário is expected to return Early May 2026 from Thigh injury. | Mario is out with thigh | Apr 25 |
| V. Behrami | MID | Out indefinitely | Hamstring | Hamstring | Apr 17 |
| M. Balotelli | A | Out indefinitely | Knock | Knock | May 27 |
| Yerry Mina | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Nov 14 |
| Luca Mazzitelli | MID | Out | Luca Mazzitelli is expected to return Early May 2026 from Muscle injury. | Mazzitelli is out with muscle | Apr 19 |
| Leonardo Pavoletti | F | Doubtful | Leonardo Pavoletti is Doubtful with Physical discomfort. | Pavoletti is doubtful with soreness | Apr 8 |
| Mattia Felici | F | Out for season | Mattia Felici is Out for season with Cruciate ligament injury. | Felici is out for season with knee | Mar 16 |
| Riyad Idrissi | DEF | Out for season | Riyad Idrissi is Out for season with Cruciate ligament injury. | Idrissi is out for season with knee | Mar 11 |
| Alberto Moreno | DEF | Out | Suspended | Suspended | Feb 18 |
| Diego Carlos | DEF | Out indefinitely | None | Carlos is injured | Jan 23 |
| Alvaro Morata | F | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Antonio Sanabria | F | Out | Suspended | Suspended | Feb 4 |
| B. Adekanye | A | Out indefinitely | Hamstring | Hamstring | Dec 30 |
| David De Gea | GK | Out indefinitely | Knock | Knock | Apr 5 |
| Moise Kean | F | Out | Suspended | Suspended | Sep 18 |
| Robin Gosens | DEF | Out | Robin Gosens is expected to return Early May 2026 from Thigh injury. | Gosens is out with thigh | Apr 23 |
| Marin Pongracic | DEF | Out | Suspended | Suspended | Mar 6 |
| Abdelhamid Sabiri | MID | Out | Suspended | Suspended | Jun 16 |
| Manor Solomon | MID | Out | Knee Injury | Knee Injury | Jan 5 |
| Tariq Lamptey | DEF | Out indefinitely | Tariq Lamptey is Unknown with Knee injury. | Lamptey is injured with knee | Aug 26 |
| Oliver Christensen | GK | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Mar 6 |
| Fabiano Parisi | DEF | Out | Fabiano Parisi is expected to return Early May 2026 from Knock injury. | Parisi is out with knock injury | Apr 19 |
| Maxwel Cornet | MID | Out | Calf/Shin Injury | Calf/Shin Injury | Mar 9 |
| Aaron Martin | DEF | Out indefinitely | Groin Strain | Groin Strain | Sep 19 |
| Caleb Ekuban | F | Out | Caleb Ekuban is expected to return Early May 2026 from Muscle injury. | Ekuban is out with muscle | Apr 26 |
| Tommaso Baldanzi | MID | Out | Tommaso Baldanzi is expected to return Early May 2026 from Muscle injury. | Baldanzi is out with muscle | Apr 26 |
| Brooke Norton-Cuffy | DEF | Out | Brooke Norton-Cuffy is expected to return Early May 2026 from Hamstring Injury. | Norton-Cuffy is out with hamstring | Apr 19 |
| Jean Akpa | MID | Out indefinitely | None | Akpa is injured | Feb 13 |
| Domagoj Bradaric | DEF | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Feb 5 |
| Amin Sarr | F | Out | Thigh Muscle Strain | Thigh Muscle Strain | Apr 11 |
| Armel Bella-Kotchap | DEF | Out | Shoulder Injury | Shoulder Injury | Apr 10 |
| Daniel Mosquera | F | Out for season | Daniel Mosquera is Out for season with Meniscus injury. | Mosquera is out for season with knee | Apr 23 |
| Nicolas Valentini | DEF | Suspended | Nicolás Valentini is serving a suspension for Yellow cards. | Valentini is suspended with yellow cards | Apr 26 |
| Daniel Oyegoke | DEF | Out | Daniel Oyegoke is expected to return Late May 2026 from Ankle injury. | Oyegoke is out with ankle | Apr 24 |
| Moatasem Al-Musrati | MID | Out indefinitely | None | Al-Musrati is injured | May 9 |
| Henrikh Mkhitaryan | MID | Out indefinitely | Back Injury | Back Injury | Mar 31 |
| Yann Sommer | GK | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Dec 6 |
| Filip Kostic | F | Out indefinitely | Virus | Virus | Jan 24 |
| Arkadiusz Milik | F | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Apr 22 |
| Teun Koopmeiners | MID | Out indefinitely | None | Koopmeiners is injured | Nov 2 |
| Juan Cabal | DEF | Doubtful | Juan Cabal is Doubtful with Muscle injury. | Cabal is doubtful with muscle | Apr 10 |
| Pedro | F | Out indefinitely | Shoulder Injury | Shoulder Injury | Sep 28 |
| Ivan Provedel | GK | Out for season | Ivan Provedel is Out for season with Shoulder injury. | Provedel is out for season with shoulder | Mar 8 |
| Samuel Gigot | DEF | Out | Ankle/Foot Injury | Ankle/Foot Injury | Mar 13 |
| Toma Basic | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 14 |
| Mario Gila | DEF | Out | Mario Gila is expected to return Early May 2026 from Thigh injury. | Gila is out with thigh | Apr 23 |
| Alessio Furlanetto | GK | Out for season | Alessio Furlanetto is Out for season with Ligament injury. | Furlanetto is out for season with ligament | Apr 16 |
| Lassana Coulibaly | MID | Out | Suspended | Suspended | May 24 |
| Riccardo Sottil | F | Doubtful | Riccardo Sottil is Doubtful with Muscle injury. | Sottil is doubtful with muscle | Apr 19 |
| Medon Berisha | F | Out indefinitely | Medon Berisha is Unknown with Hamstring Injury. | Berisha is injured with hamstring | Apr 19 |
| Kialonda Gaspar | DEF | Doubtful | Kialonda Gaspar is Doubtful with Knee injury. | Gaspar is doubtful with knee | Apr 19 |
| Matija Frigan | F | Out | Matija Frigan is expected to return Mid May 2026 from Cruciate ligament injury. | Frigan is out with knee | Apr 8 |
| Daniel Tyrell Denoon | DEF | Doubtful | Daniel Denoon is Doubtful with Muscle injury. | Denoon is doubtful with muscle | Mar 16 |
| Marius Marin | MID | Doubtful | Marius Marin is Doubtful with Muscle injury. | Marin is doubtful with muscle | Apr 19 |
| Matteo Tramoni | MID | Doubtful | Matteo Tramoni is Doubtful with Physical discomfort. | Tramoni is doubtful with soreness | Apr 24 |
| Lorenzo Pellegrini | MID | Out | Lorenzo Pellegrini is expected to return Early May 2026 from Muscle injury. | Pellegrini is out with muscle | Apr 19 |
| Angelino | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Sep 13 |
| Kostas Tsimikas | DEF | Out | Knock | Knock | Aug 15 |
| Zeki Celik | DEF | Out | Suspended | Suspended | Feb 20 |
| A. Tripaldelli | DEF | Out indefinitely | Knock | Knock | Nov 25 |
| Romelu Lukaku | F | Out | Romelu Lukaku is expected to return Early November 2025 from Thigh injury. | Lukaku is out with thigh | Oct 20 |
| Frank Anguissa | MID | Out | Suspended | Suspended | Feb 8 |
| Stanislav Lobotka | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Dec 12 |
| Mathias Olivera | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 4 |
| Eljif Elmas | MID | Out indefinitely | None | Elmas is injured | Jan 1 |
| Nemanja Matic | MID | Out indefinitely | Calf/Shin Injury | Calf/Shin Injury | Feb 21 |
| Armand Lauriente | F | Out | Back Injury | Back Injury | Nov 14 |
| Edoardo Pieragnolo | DEF | Doubtful | Edoardo Pieragnolo is Doubtful with Muscle injury. | Pieragnolo is doubtful with muscle | Dec 28 |
| Daniel Boloca | MID | Out | Daniel Boloca is expected to return Early May 2026 from Meniscus injury. | Boloca is out with knee | Apr 8 |
| Jeroen Zoet | GK | Out indefinitely | Knock | Knock | Oct 20 |
| Daniele Verde | MID | Out indefinitely | Hamstring | Hamstring | May 5 |
| Adam Masina | DEF | Out indefinitely | Knee Injury | Knee Injury | Dec 29 |
| Adrien Tameze | MID | Out | Back Injury | Back Injury | Oct 6 |
| Guillermo Maripan | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 13 |
| Enzo Ebosse | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Sep 9 |
| Zannetos Savva | MID | Doubtful | Savva, Zannetos: doubtful - injured | Savva is doubtful | Aug 22 |
| Sandro Kulenovic | F | Suspended | Sandro Kulenovic is serving a suspension for Yellow cards. | Kulenovic is suspended with yellow cards | Dec 21 |
| Kingsley Ehizibue | DEF | Out indefinitely | Concussion | Concussion | Apr 17 |
| Adam Buksa | F | Out | Ankle Ligaments | Ankle Ligaments | Apr 11 |
| Nicolo Bertola | DEF | Out | Nicolò Bertola is expected to return Early May 2026 from Muscle injury. | Bertola is out with muscle | Apr 17 |
Benevento Calcio
Brescia Calcio
FC Crotone
S.P.A.L. 2013
