Astros vs. Cardinals Odds & Betting Predictions - April 16, 2025

Astros at Cardinals

5:15 pm • SCHN2

Houston Astros

47-33

1 - 4

St. Louis Cardinals

44-37

pitcher		team	era	w-l
S.Matz			3.50	4-2
R.Blanco			4.10	3-4

MatchupOpenSpreadTotalMoneyline
Astros 47-33	-1.5	-1.5+152	o8.5-106	-111
Cardinals 44-37	u8.5	+1.5-175	u8.5-114	-108

Wednesday 5:15 p.m.

April 16, 2025

Busch StadiumSt. Louis

STL -101

0.99u

#BQ

R.Blanco u4.5 Ks+110

0.55u

#Tailing @The_Oddsmaker

HOU -1.5+165

R.Blanco u4.5 Ks+120

0.5u

Tailing @The_Oddsmaker

R.Blanco u4.5 Ks+120

1.2u

Proj closer to -140. Blanco is off to a hot start with a 30% K rate but his underlying metrics are pretty much in line with where we would normally expect him in the 23.5% range. He’s benefited from an easier schedule so far with 2 of the 3 games coming at home (he has a 5% higher K rate at home in his career). This is his toughest matchup yet, on the road, during the day (his K rate is 3% lower in day games over last 3 seasons)

R.Blanco u4.5 Ks+120

0.48u

2.02% ev

S.Matz u3.5 Ks-170

1.5u

3.62% ev

Y.Alvarez o1.5 Hits + Runs + RBIs-125

1.25u

HOU -114

No props found

MLB Public Betting

Cardinals are 3-2 in their last 5 games.
Cardinals are 2-3 in their last 5 games against the spread
Cardinals are 21-18 in their road games against the spread
The totals have gone OVER in 3 of Cardinals' last 5 games
The totals have gone OVER in 23 of Cardinals' 42 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	44-37	23-19	21-18	14-21	29-16
Astros	42-38	23-19	19-19	25-31	17-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	43-35-3	23-18-1	20-17-2	20-13-2	22-22-1
Astros	32-45-3	16-26	16-19-3	26-29-1	5-16-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	44-37	26-16	18-21	19-16	24-21
Astros	47-33	29-13	18-20	34-22	13-10

date	opponent	score	spread	over/under	moneyline
Apr 15th	HOU	L 0-2	+1.5 L	U 7.5	HOU +114
Apr 14th	HOU	W 8-3	+1.5 W	O 7	STL -110
Apr 13th	PHI	W 7-0	+1.5 W	U 8	STL +142
Apr 12th	PHI	L 1-4	+1.5 L	U 8	PHI +150
Apr 12th	PHI	W 2-0	+1.5 W	U 7.5	STL -107

Lance McCullers
SP
Lance McCullers (foot) has been scratched Monday. Ryan Gusto will start for the Astros.
Out
Taylor Trammell
LF
Trammell is out with calf
Out
Cristian Javier
SP
Javier is out with elbow
Out
Luis Garcia
SP
Garcia is out with elbow
Out
Pedro Leon
RF
Leon is out with knee
Out
J.P. France
SP
France is out with shoulder
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out
Spencer Arrighetti
SP
Arrighetti is out with thumb
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RR.Blanco, P	88	5	1	3
RL. VanWey, P	14	0.1	0	0
LS.Okert, P	19	1.1	1	0
RT.Scott, P	13	1	0	0
LB.Sousa, P	4	0.1	0	0

HITTERS	H-AB	R	RBI
1J.Altuve, DH	2-4	1	0
2J.Pena, SS	1-4	0	0
3I.Paredes, 3B	0-3	0	1
4C.Walker, 1B	0-4	0	0
5Y.Diaz, C	1-4	0	0
6B.Rodgers, 2B	0-3	0	0
7J.Meyers, CF	0-3	0	0
8C.Smith, RF	0-3	0	0
9C.McCormick, LF	0-3	0	0

PITCHER	PC	IP	K	ER
LS.Matz, P	71	5	5	1
RR.Fernandez, P	12	1	1	0
RK.Leahy, P	14	1	1	0
RP.Maton, P	10	1	1	0
RR.Helsley, P	21	1	0	0

HITTERS	H-AB	R	HR	RBI
1L.Nootbaar, LF	1-3	1	1	3
2W.Contreras, DH	0-4	0	0	0
3B.Donovan, 2B	1-3	0	0	0
4N.Arenado, 3B	0-4	0	0	0
5A.Burleson, 1B	1-4	0	0	0
6J.Walker, RF	1-4	1	0	0
6M.Siani, CF	0-0	0	0	0
7Y.Pozo, C	1-3	0	0	0
8V.Scott, CF	1-3	1	0	0
8V.Scott, RF	1-3	1	0	0
9T.Saggese, SS	2-4	1	0	1