White Sox vs. Guardians Odds & Betting Predictions - October 5, 2026

White Sox at Guardians

9:00 pm • truTV
4 - 3
Starting Pitchers
pitcherteameraw-l
Gavin Williams logoG.WilliamsCleveland Guardians logo3.600-0
Anthony Kay logoA.KayChicago White Sox logo3.861-0

White Sox at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
White Sox
2-0
+1.5
+1.5-178
o6.5-120
+130
Guardians
0-2
u6.5
-1.5+150
u6.5+100
-156
location pinMonday 9:00 p.m.
October 05, 2026
Progressive FieldCleveland
White Sox vs. Guardians Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 94-69-0 (+23.2u)
Under 8.5 (Live)-140
1u
Under 8.5 (Live)-105
1u
Under 7.5 (Live)-138
1u
Under 6.5 (Live)+100
1u
Frank Ammirante
Frank Ammirante
Last 30d: 104-113-2 (-17.7u)
G.Williams u7.5 Ks-112
1.12u
OldSchool0909
Last 30d: 86-136-2 (-50.4u)
CWS +138
1.38u
Topper
Topper
Last 30d: 190-191-8 (-10.4u)
CWS +130
1.3u
*Playoff Dogs* Overall: 86-66-0,57% (ROI:29%) Season:1-0-0,100% (ROI:130%) #TSA
Scott Rickenbach
Scott Rickenbach
Last 30d: 83-87-2 (-15.0u)
Over 6.5-112
0.89u
Matt Trollo
Matt Trollo
Last 30d: 29-36-2 (-1.3u)
G.Williams o7.5 Ks+104
1.04u
(Novig) I know Sean went against this on today's Payoff Pitch, partially because Williams has struggled against the White Sox, but just too much moving in his favor. Weather not necessarily K friendly (-1%), BUT it is cold and will knock down fly balls with the wind blowing in at double digits. Williams biggest problem 3.84 xERA due to 11.4% Barrels/BBE, 46.6 HardHit%. Knocking down some of those fly balls should allow him to pitch deeper into this game. Williams 35.3 K% v LHBs (30.2% v RHBs). I’m projecting 23 batters with these weather conditions, which would be 16 from LH side. First 23 in CWS order avg 24.6 K% vs RHP. With this lineup construction, the park offers a 4% strikeout boost with Gabe Morales nearly another 6%. Take away the 1% for weather and Williams gets around a 9% environmental boost. I think this is a massive upside spot for Williams and would even play him if I projected only 21 batters. Novig is currently offering 48.5-49% (+106 to +104). If you can only get something above -110, I’d cut to 0.5u and would play to around -140.
Sandy Plashkes
Sandy Plashkes
Last 30d: 97-74-3 (+51.9u)
G.Williams o7.5 Ks-112
1u
Collin Whitchurch
Collin Whitchurch
Last 30d: 82-101-1 (+2.7u)
No Home Runs Hit In Game+300
0.51u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 56-124-2 (-14.8u)
No Home Runs Hit In Game+300
0.99u
Doug Ziefel
Doug Ziefel
Last 30d: 330-391-9 (+3.6u)
C.DeLauter o0.5 SB+900
0.06u
Collin Whitchurch
Collin Whitchurch
Last 30d: 82-101-1 (+2.7u)
A.Kay o0.5 BB-130
0.5u
Doug Ziefel
Doug Ziefel
Last 30d: 330-391-9 (+3.6u)
M.Murakami Over0.5 Hitter Walks+130
0.38u
J.Ramirez Over0.5 Hitter Walks+170
0.49u
Under 6.5+100
0.5u

White Sox vs. Guardians Previews & Analysis

  • White Sox vs Guardians: Sean Paul's Pick for AL Division Series Game 2 article feature image

    White Sox vs Guardians: Sean Paul's Pick for AL Division Series Game 2

    Sean Paul•
    Oct 5, 2026 UTC
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Prop Odds Comparison

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White Sox vs. Guardians Public Betting Percentages

Away Logo

White Sox

Public

45%

Bets%

55%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
79-8336-4543-3843-5536-24
White Sox
92-7049-3243-3828-2363-46

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
77-8542-3935-4648-5027-33
White Sox
92-69-145-35-147-3427-23-163-46

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
0-241-4044-3755-4330-30
White Sox
4-048-3336-4530-2153-56

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 3rdCWSL 0-3-1.5 LU 6.5CWS -149
Sep 27th@KCL 2-3-1.5 LU 8KC -109
Sep 26th@KCW 11-5-1.5 WO 8.5CLE -113
Sep 25th@KCW 12-9-1.5 WO 7CLE -145
Sep 24th@BOSW 1-0+1.5 WU 6.5CLE +110

Guardians vs. White Sox Injury Updates

Guardians Injuries

    White Sox Injuries

    • Mike Vasil
      RP

      Vasil is out with elbow

      Out

    • Ky Bush
      SP

      Bush is out with elbow

      Out

    • Brooks Baldwin
      LF

      Baldwin is out with elbow

      Out

    • Drew Thorpe
      SP

      Thorpe is out with elbow

      Out

    White Sox vs. Guardians Box Score
    White Sox Player Stats
    Projected
    PITCHERPCIPKER
    Anthony Kay logoLA.Kay, P170.101
    Sean Newcomb logoLS.Newcomb, P40230
    Sean Burke logoRS.Burke, P835.161
    Grant Taylor logoRG.Taylor, P71.100
    HITTERSH-ABRHRRBI
    Sam Antonacci logo1S.Antonacci, LF0-4000
    Kyle Teel logo2K.Teel, C1-4100
    Miguel Vargas logo3M.Vargas, 3B1-2100
    Munetaka Murakami logo4M.Murakami, 1B1-4001
    Andrew Benintendi logo5A.Benintendi, DH0-2000
    Randal Grichuk logo5R.Grichuk, PH0-1100
    Randal Grichuk logo5R.Grichuk, DH0-1100
    Tristan Peters logo6T.Peters, CF0-2000
    Tommy Pham logo6T.Pham, PH0-1000
    Brenton Doyle logo6B.Doyle, CF0-1000
    Braden Montgomery logo7B.Montgomery, RF1-4102
    Chase Meidroth logo8C.Meidroth, 2B2-4001
    Colson Montgomery logo9C.Montgomery, SS0-3000
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Gavin Williams logoRG.Williams, P985112
    Erik Sabrowski logoLE.Sabrowski, P110.202
    Hunter Gaddis logoRH.Gaddis, P17110
    Shawn Armstrong logoRS.Armstrong, P161.110
    Cade Smith logoRC.Smith, P5100
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, CF1-4100
    Jose Ramirez logo2J.Ramirez, 3B0-3100
    Chase DeLauter logo3C.DeLauter, RF2-4100
    Jo Adell logo4J.Adell, DH1-3001
    Nathaniel Lowe logo5N.Lowe, 1B0-4001
    Angel Martinez logo6A.Martinez, LF0-4000
    Travis Bazzana logo7T.Bazzana, 2B0-3000
    Patrick Bailey logo8P.Bailey, C0-4000
    Brayan Rocchio logo9B.Rocchio, SS0-3000

    White Sox vs. Guardians Odds Comparison

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    White Sox at Guardians Team Totals

    MatchupOverUnder
    White Sox
    2-0
    N/A
    N/A
    Guardians
    0-2
    N/A
    N/A