Giants vs. Diamondbacks Odds & Betting Predictions - September 16, 2025

Giants at Diamondbacks

1:40 am • NBCS-BA

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San Francisco Giants

@

Arizona Diamondbacks

pitcher		team	era	w-l
Z.Gallen			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Giants 75-72	N/A	N/A	N/A
Diamondbacks 73-75	N/A	N/A	N/A

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Tuesday 1:40 a.m.

September 16, 2025

Chase FieldPhoenix

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94°Fahrenheit

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0%Rain

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4Wind

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MLB Public Betting

Diamondbacks are 1-4 in their last 5 games.
Diamondbacks are 2-3 in their last 5 games against the spread
Diamondbacks are 40-35 in their road games against the spread
The totals have gone OVER in 4 of Diamondbacks' last 5 games
The totals have gone OVER in 35 of Diamondbacks' 72 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Diamondbacks	75-72	35-37	40-35	34-49	40-23
Giants	69-78	32-41	37-37	33-53	35-24

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Diamondbacks	73-69-5	35-33-4	38-36-1	41-38-4	32-30-1
Giants	68-74-5	30-42-1	38-32-4	32-53-1	34-21-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Diamondbacks	73-75	38-34	35-40	42-41	30-33
Giants	75-72	38-35	37-37	46-40	28-31

date	opponent	score	spread	over/under	moneyline
Sep 13th	@MIN	L 8-9	+1.5 W	O 8.5	MIN +120
Sep 10th	@SF	W 5-3	+1.5 W	U 9	ARI +110
Sep 10th	@SF	L 3-5	+1.5 L	O 7.5	SF +121
Sep 9th	@SF	L 5-11	+1.5 L	O 7.5	SF +150
Sep 7th	BOS	L 4-7	+1.5 L	O 8.5	BOS -112

Tom Murphy
C
Murphy is out with back
Out
JT Brubaker
RP
Brubaker is out with ribs
Out

James McCann
C
James McCann has been scratched Friday.
Out
John Curtiss
RP
Curtiss is out with elbow
Out

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MatchupOverUnder
Giants 75-72	N/A	N/A
Diamondbacks 73-75	N/A	N/A