Giants vs. Dodgers Odds & Betting Predictions - September 21, 2025

Giants at Dodgers

8:10 pm • NBCS-BA

San Francisco Giants

3

3 - 1

Los Angeles Dodgers

1

pitcher		team	era	w-l
E.Sheehan			2.86	6-3
T.McDonald			3.38	0-0

MatchupOpenSpreadTotalMoneyline
Giants 77-80	+1.5	+1.5-110	o9-119	+178
Dodgers 88-68	u9	-1.5-113	u9-105	-228

location pin

Sunday 8:10 p.m.

September 21, 2025

Dodger StadiumLos Angeles

SF +1.5-110

1.14u

No props found

MLB Public Betting

Dodgers are 4-1 in their last 5 games.
Dodgers are 3-2 in their last 5 games against the spread
Dodgers are 32-43 in their road games against the spread
The totals have gone OVER in 1 of Dodgers' last 5 games
The totals have gone OVER in 40 of Dodgers' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Dodgers	69-87	37-44	32-43	59-80	10-7
Giants	73-84	32-44	41-40	33-55	39-28

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Dodgers	72-77-7	40-35-6	32-42-1	63-69-7	9-8
Giants	73-77-7	33-42-1	40-35-6	34-53-1	37-24-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Dodgers	88-68	52-29	36-39	80-59	8-9
Giants	77-80	38-38	39-42	46-42	30-37

date	opponent	score	spread	over/under	moneyline
Sep 21st	SF	W 7-5	-1.5 W	O 9	LAD -240
Sep 20th	SF	W 6-3	-1.5 W	U 9	LAD -197
Sep 19th	SF	W 2-1	-1.5 L	U 7.5	LAD -173
Sep 18th	PHI	W 5-0	-1.5 W	U 7.5	LAD -153
Sep 17th	PHI	L 6-9	-1.5 L	O 7.5	PHI -133

Michael Kopech
RP
Kopech is out with arm
Out
Michael Grove
RP
Grove is out with shoulder
Out
River Ryan
SP
Ryan is out for season with elbow
Out for Season
Gavin Stone
SP
Stone is out for season with shoulder
Out for Season
Roki Sasaki
SP
Sasaki is out with shoulder
Out

Tom Murphy
C
Murphy is out with back
Out
JT Brubaker
RP
Brubaker is out with ribs
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RT.McDonald, P		89	6	3	1
RS.Bivens, P		8	1	0	0
LJ.Lucchesi, P		17	1.1	2	0
RR.Walker, P		13	0.2	1	0

HITTERS	H-AB	R	HR	RBI
1H.Ramos, LF	0-4	0	0	0
1G.McCray, LF	0-0	0	0	0
2R.Devers, DH	1-3	0	0	0
3W.Adames, SS	0-3	0	0	1
4M.Chapman, 3B	0-4	0	0	1
5B.Eldridge, 1B	0-3	0	0	0
6J.Lee, CF	0-4	0	0	0
7C.Koss, 2B	2-4	1	0	0
8D.Gilbert, RF	1-4	1	0	0
9A.Knizner, C	0-1	0	0	0
9P.Bailey, PH	1-2	1	0	1
9P.Bailey, C	1-2	1	0	1

PITCHER		PC	IP	K	ER
RE.Sheehan, P		84	7	10	0
RB.Treinen, P		30	0.2	0	3
LA.Vesia, P		2	0.1	0	0
RW.Klein, P		6	1	0	0

HITTERS	H-AB	R	HR	RBI
1S.Ohtani, DH	1-4	0	0	0
2M.Betts, SS	0-4	0	0	0
3F.Freeman, 1B	1-4	0	0	0
4M.Muncy, 3B	1-3	1	0	0
5A.Pages, CF	1-4	0	0	0
5A.Pages, RF	1-4	0	0	0
6M.Conforto, LF	1-4	0	0	1
7M.Rojas, 2B	0-2	0	0	0
8A.Call, RF	1-2	0	0	0
8T.Edman, PH	0-1	0	0	0
8T.Edman, CF	0-1	0	0	0
9D.Rushing, C	1-3	0	0	0

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MatchupOverUnder
Giants 77-80	o3.5-122	u3.5-106
Dodgers 88-68	o5-124	u5.5-137