The Toronto Blue Jays host the Boston Red Sox on April 29, 2026. First pitch from Rogers Centre is scheduled for 3:07 p.m. EDT. The game will be broadcast on NESN.
The Blue Jays are favored by -130 on the moneyline and by -1.5 on the run line. The Red Sox are +110 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Red Sox vs Blue Jays prediction below, as well as probable pitchers, weather report, and more.
Red Sox vs Blue Jays Prediction
- Red Sox vs Blue Jays Pick: Vladimir Guerrero Jr. Over 1.5 Total Bases
My Red Sox vs Blue Jays best bet is on Vladdy's total bases prop. Make sure to find the best odds by checking our live MLB odds page.
Red Sox vs Blue Jays Odds
| Red Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -194 | 8.5 -102o / -120u | +110 |
| Blue Jays Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +160 | 8.5 -102o / -120u | -130 |
- Red Sox vs Blue Jays moneyline: Red Sox +110, Blue Jays -130
- Red Sox vs Blue Jays over/under: 8.5 (-102 / -120)
- Red Sox vs Blue Jays spread: Red Sox +1.5 (-194), Blue Jays -1.5 (+160)
Red Sox vs Blue Jays MLB Betting Preview
Toronto Blue Jays Player Prop
Brayan Bello is on the mound for Boston after a concerning start to his 2026 campaign. He’s recorded a whopping 9.00 ERA with a 2.27 WHIP across his first five starts of the season. His command isn’t there, and he’s already allowed 37 hits across 22 frames.
Bello has been trying to mix up his tempo more, throwing more sinkers and cutters rather than four-seamers in an attempt to salvage his batted-ball profile.
Though Vladdy’s power numbers haven’t been elite so far (two home runs), he has been remarkably efficient in the box (.340 average).
Across his five seasons in Boston, Bello has faced off against Vladimir Guerrero Jr. exactly 30 times. Over those plate appearances, Vladdy is hitting .400 with four doubles and two homers.
Pick: Vladimir Guerrero Jr. Over 1.5 Total Bases
