The Cincinnati Reds host the Chicago Cubs on September 18, 2026. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on MARQ.
The Cubs are favored by -126 on the moneyline and by -1.5 on the run line. The Reds are +108 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Cubs vs Reds prediction below, as well as probable pitchers, weather report, and more.
Cubs vs Reds Prediction
- Cubs vs Reds Pick: Under 8.5 (-100)
My Cubs vs Reds best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page and download the Action Network app for more picks and analysis.
Cubs vs Reds Odds
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +126 | 8.5 -122o / -100u | -126 |
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -152 | 8.5 -122o / -100u | +108 |
- Cubs vs Reds moneyline: Cubs -126, Reds +108
- Cubs vs Reds over/under: 8.5 (-122o / -100u)
- Cubs vs Reds spread: Cubs -1.5 (+126), Reds +1.5 (-152)
Cubs vs Reds Probable Pitchers
| Clay Holmes (RHP, CHC) | Stat | Chase Burns (RHP, CIN) |
|---|---|---|
| 6-7 | W-L | 15-3 |
| 1.7 | fWAR (FanGraphs) | 4.4 |
| 2.85/3.95 | ERA / xERA | 2.80/3.19 |
| 3.58/3.75 | FIP / xFIP | 3.17/3.42 |
| 9.8% | K-BB% | 20.7% |
| 59.9% | GB% | 37.0% |
| .247 | BABIP | .287 |
| 97 | Stuff+ | 112 |
| 100 | Location+ | 101 |
Cubs vs Reds MLB Betting Preview
Sean Zerillo's projections show solid value on the total for this Cubs vs. Reds matchup, with an 7.2% edge on the under.
If you want to dive deeper into this game, it'd be wise to check out BARTOLO, Zerillo's new PRO baseball tool that gives you access to all the input data he uses to project games every day.
Cubs vs Reds Pick, Betting Analysis
BARTOLO projects the Cubs for 4.17 runs and the Reds for 3.61 today, bringing the total under the current 8.5 runs line.
As they try to break a four-game road losing streak against Cincinnati, Chicago sends Clay Holmes (6-7, 2.85 ERA, 1.15 WHIP, 71 Ks) to the mound.
Holmes will go up against Reds starter Chase Burns, who boasts a dominant campaign (15-3, 2.80 ERA, 1.15 WHIP, 181 Ks).
Burns will make his penultimate start of 2026 in a shortened outing, piggybacked by left-hander Brandon Williamson.
Pick: Under 8.5 (-100)
