Boston Col vs. Louisville Odds & Betting Predictions - October 25, 2025

Boston Col at Louisville

11:30 pm • ACC Network

Boston College Eagles

@

Louisville Cardinals

MatchupOpenSpreadTotalMoneyline
Boston Col 1-6	+22.5	+23.5-105	o53.5-110	+1280
Louisville 5-1	u53.5	-23.5-115	u53.5-110	-3000

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Saturday 11:30 p.m.

October 25, 2025

L&N Federal Credit Union StadiumLouisville

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55°Fahrenheit

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24%Rain

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6Wind

No props found

NCAAF Public Betting

Louisville are 4-1 in their last 5 games.
Louisville are 1-4 in their last 5 games against the spread
Louisville are 2-0 in their road games against the spread
The totals have gone OVER in 3 of Louisville' last 5 games
The totals have gone OVER in 2 of Louisville' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Louisville	2-4	0-4	2-0	1-4	1-0
Boston Col	2-5	1-3	1-2	1-2	1-3

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Louisville	3-3	2-2	1-1	3-2	0-1
Boston Col	5-2	2-2	3-0	2-1	3-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Louisville	5-1	N/A	N/A	4-1	1-0
Boston Col	1-6	N/A	N/A	1-2	0-4

date	opponent	score	spread	over/under	moneyline
Oct 17th	@MIA	W 24-21	+10.5 W	U 49.5	LOU +340
Oct 4th	UVA	L 27-30	-6.5 L	U 60	UVA -245
Sep 27th	@PITT	W 34-27	-6.5 W	O 53.5	LOU -155
Sep 20th	BGSU	W 40-17	-26.5 L	O 50.5	LOU -4000
Sep 5th	JMU	W 28-14	-15.5 L	U 56.5	LOU -690

Total

Passing

1703

YDS

1693

145/224

Comps/Atts

152/229

7.6

YPA

7.39

11/5

TDs/INTs

10/5

12/92

Sacks/Yards

14/120

Rushing

510

Rush Yards

694

164

Attempts

181

3.11

YPC

3.83

9

TDs

11

Turnovers

Fumbles Lost

5

Interceptions

5

Efficiency

19/24 79.2%

Redzone

18/19 94.7%

33/77 0%

3rd Down

36/84 0%

4/9 0%

4th Down

3/5 0%

First Downs

116

Total

130

76

Pass

76

33

Rush

43

7

Penalty

11

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Boston Col 1-6	N/A	N/A
Louisville 5-1	N/A	N/A