The Memphis Tigers take on the Florida Atlantic Owls in Boca Raton, Florida. Kickoff is set for 7 p.m. ET on ESPN2.
Memphis is favored by 13.5 points on the spread with a moneyline of -525. The total is set at 63.5 points.
Here’s my Memphis vs. FAU prediction and college football picks for Saturday, September 27, 2025.
Memphis vs FAU Prediction
- Memphis vs. FAU Pick: FAU +14 or Better
My FAU vs. Memphis best bet is on the Owls to cover as two-touchdown 'dogs. Find the best line available on our live NCAAF odds page.
Memphis vs FAU Odds
| Memphis Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-13.5 -110 | 63.5 -110o / -110u | -525 |
| FL Atlantic Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+13.5 -110 | 63.5 -110o / -110u | +390 |
- Memphis vs FAU point spread: Memphis -13.5
- Memphis vs FAU over/under: 63.5 points
- Memphis vs FAU moneyline: Memphis -525, FAU +390
Memphis vs FAU Picks
This may be the peak of the market for Memphis after its fairly fortunate win over an Arkansas team it caught in a favorable situational spot (yet the Tigers still trailed 28-10 at one point).
Memphis' other three victories came against Chattanooga, Georgia State, and a Troy team that lost its starting quarterback to an injury early in the game.
While the Tigers found themselves in an emotional (and physically demanding) battle with Arkansas last week, FAU enjoyed a bye week, which could prove extra beneficial for a completely brand new team under a new regime that implemented new schemes.
The offense needed to work on getting the timing down. So far, the quarterback and receivers have not been on the same page, which has led to a whopping nine interceptions (and subsequently a -8 turnover margin) against the two FBS opponents the snake-bit Owls have faced.
I expect Caden Veltkamp and that side of the ball to look much sharper on Saturday in FAU's pass-happy Air Raid offense. If that's the case, the Owls should score enough to stay within two touchdowns against a Memphis defense that is much more vulnerable against the pass.
For what it's worth, Memphis head coach Ryan Silverfield is just 8-16 ATS (33.3%) as a conference favorite.
Pick: FAU +14 or Better
