The Southern Miss Golden Eagles take on the Arkansas State Red Wolves in Jonesboro, Arkansas. Kickoff is set for 12:00 p.m. EST on ESPNU.
Southern Miss is favored by 4.5 points on the spread with a moneyline of -200. The total is set at 56.5 points.
Here’s my Southern Miss vs. Arkansas State predictions and college football picks for Saturday, November 8, 2025.
Southern Miss vs Arkansas State Prediction
- Southern Miss vs. Arkansas St Pick: Southern Miss -4.5 (-110, bet365)
My Arkansas State vs. Southern Miss best bet is on the Golden Eagles. Find the best line available on our live NCAAF odds page.
Southern Miss vs Arkansas State Odds
| Southern Miss Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4.5 -110 | 56.5 -110o / -110u | -200 |
| Arkansas State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4.5 -110 | 56.5 -110o / -110u | +165 |
- Southern Miss vs Arkansas State point spread: Southern Miss -4.5 (-110), Arkansas State +4.5 (-110)
- Southern Miss vs Arkansas State over/under: 56.5 (-110o / -110u)
- Southern Miss vs Arkansas State moneyline: Southern Miss -200, Arkansas State +165
Southern Miss vs Arkansas State Preview
Duck and I talked about Southern Miss at 40-to-1 to win the Sun Belt in the preseason. The Golden Eagles are closer to 3-to-1 entering this game, with the second-shortest odds in the conference.
The offense has been consistent. Braylon Braxton is playing well, but the team has also found a running game with Jeffery Pittman having returned from injury.
That’s key because Arkansas State is good at defending the run, but the Red Wolves are a weak defense overall, including a very weak pass rush.
If you have balance and make Arkansas State defend both, you’ll move the football.
Arkansas State hasn’t looked that impressive. The Red Wolves haven’t had any pop on the ground since Ja’Quez Cross got hurt. They’ve become one-dimensional, and most solid pass defenses have held them at bay.
Southern Miss has a good pass defense, ranking in the top 15 nationally in Pass Success Rate allowed and EPA per Dropback allowed.
Additionally, Jaylen Raynor has had some turnover issues. He has 17 Turnover Worthy Plays on the season, the most among Group of 5 quarterbacks.
Pick: Southern Miss -4.5 (-110, bet365)
