Here are our Iowa State vs. BYU prediction and best CFB prop bets today, live from the Polymarket board. Get the Polymarket promo code ACTION for a new $25 trading bonus from one of the best prediction market promos and trade Friday night's Big 12 matchup.
No. 8 BYU hosts Iowa State on Friday Night Football, and this Iowa State vs. BYU prediction rounds up our best college football bets today straight from the live Polymarket board.
- BYU is 4-0 and unbeaten through its first real Big 12 test, while Iowa State is 3-2 under first-year coach Jimmy Rogers, fresh off a three-point win over West Virginia.
- Kickoff is 10:15 p.m. ET at LaVell Edwards Stadium in Provo, with BYU laying 10.5 points and the total sitting at 45.5.
Here is our full picks table for Iowa State vs. BYU before we break down each pick and market on the board tonight.
| 🏈 CFB Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| BYU to Win | Yes | 78¢ | $28.21 | Trade it on Polymarket! |
| BYU -10.5 | Yes | 49¢ | $104.08 | Trade it on Polymarket! |
| Over 45.5 | Yes | 52¢ | $92.31 | Trade it on Polymarket! |
| Under 45.5 | Yes | 49¢ | $104.08 | Trade it on Polymarket! |
| Iowa State +10.5 | Yes | 52¢ | $92.31 | Trade it on Polymarket! |
| Iowa State to Win | Yes | 23¢ | $334.78 | Trade it on Polymarket! |
Best Iowa State vs. BYU Picks on Polymarket
Every pick below is a real trade we'd make after redeeming the Polymarket promo code ACTION, ranked from the safest number down to the long shots.
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Best Moneyline Pick Today – BYU to Win
| 🏈 CFB Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It |
|---|---|---|---|
| BYU to Win | Yes | 78¢ | $28.21 | Trade it now on Polymarket! |
BYU is 4-0 and ranked No. 8, and the Cougars are a perfect 2-0 against the spread this season when favored by 10.5 points or more. Iowa State is 3-2 under first-year coach Jimmy Rogers, and while the Cyclones just beat West Virginia 45-42, they've yet to face a defense like BYU's, which ranks top-25 nationally in yards allowed.
At 78 cents, a $100 buy works out to roughly 128 shares.
- If BYU wins: this ticket nets a profit of $28.21.
- If not: the $100 stake is lost entirely.
The safest number on the board tonight, but still returns better than 28 cents on the dollar.
Best Spread Pick Today – BYU -10.5
| 🏈 CFB Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It |
|---|---|---|---|
| BYU -10.5 | Yes | 49¢ | $104.08 | Trade it now on Polymarket! |
BYU has covered double-digit spreads twice already this season, and Iowa State is dealing with a clear talent gap against a Cougars roster that's rolled through its first four games. BYU is banged up — star running back LJ Martin and linebacker Isaiah Glasker are both questionable — but the Cougars have shown they can win big even when Martin is limited.
At 49 cents, a $100 buy is roughly 204 shares.
- If BYU wins by 11 or more: profit of $104.08.
- If not: the $100 stake is a total loss.
A near coin-flip number that still pays out more than double your stake.
Best Total Pick Today – Under 45.5
| 🏈 CFB Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It |
|---|---|---|---|
| Under 45.5 | Yes | 49¢ | $104.08 | Trade it now on Polymarket! |
LJ Martin left last week's game against TCU after two carries, and BYU's offense cratered without him — 3.5 yards per play and just 17 points after averaging 44.0 points per game entering that matchup. If Martin is limited again, this could be another grind-it-out night for the Cougars offense.
At 49 cents, a $100 buy is roughly 204 shares.
- If the combined score stays under 45.5: profit of $104.08.
- If not: the $100 stake is a total loss.
Best Longshot Pick Today – Iowa State to Win
| 🏈 CFB Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It |
|---|---|---|---|
| Iowa State to Win | Yes | 23¢ | $334.78 | Trade it now on Polymarket! |
Iowa State owns a 5-1 series edge over BYU historically, and quarterback Jaylen Raynor just threw for 264 yards in the win over West Virginia. With BYU dealing with injuries to Martin and Glasker, a true upset isn't out of the question.
At 23 cents, a $100 buy is roughly 435 shares.
- If Iowa State wins outright: profit of $334.78.
- If not: the $100 stake is a total loss.
The deepest longshot on the board, paying out nearly 4.3-to-1.
Iowa State vs. BYU Moneyline
BYU Moneyline
BYU is priced as the clear home favorite, trading at 78¢ to win outright tonight on Polymarket.
Iowa State Moneyline
Iowa State is the road underdog, trading at 23¢ to win outright.
Spread and Total for Iowa State vs. BYU
Iowa State vs. BYU Spread
BYU to win by more than 10.5 points is priced at 49¢ Yes against 52¢ No.
Iowa State vs. BYU Total
The total sits at 45.5 points, priced at 52¢ Yes on the over against 49¢ No on the under.
What's Moving the Market
Prediction markets and prices move for several reasons tonight. BYU's offense completely stalled last week without LJ Martin on the field, and his questionable tag — alongside linebacker Isaiah Glasker's absence on defense — is the clearest reason Iowa State's number has held up despite BYU's unbeaten record.
Iowa State, meanwhile, just needed a three-point win over West Virginia to get to 3-2, and Raynor's inconsistent play (including a rough outing in poor weather against TCU) is why BYU remains a heavy favorite even banged up.
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Final Thoughts: Iowa State vs. BYU Prediction
BYU looks like the better team across almost every number on the board tonight, but LJ Martin's health is the swing factor for both the spread and the total, while Iowa State's path runs through forcing a clean game out of a defense that's been dominant through four weeks. That wraps our full Iowa State vs. BYU prediction and every best CFB pick we'd make on the Polymarket board.
Iowa State vs. BYU Prediction FAQs
Who wins the Iowa State vs. BYU prediction tonight? Polymarket favors BYU at 78¢ to win outright, with the Cougars also laying 10.5 points on the spread.
What time does Iowa State vs. BYU kick off? This Big 12 matchup kicks off Friday, October 9, 2026 at 10:15 p.m. ET from LaVell Edwards Stadium in Provo, airing on ESPN.
How do I use the Polymarket promo code for Iowa State vs. BYU? Create an account, deposit at least $10, and enter code ACTION to unlock a new $25 trading bonus before kickoff.
What is the total for Iowa State vs. BYU? The total sits at 45.5 points, priced at 52¢ Yes on the over and 49¢ Yes on the under.
