Commanders vs. 49ers Odds & Betting Predictions - October 20, 2026

Commanders at 49ers

12:15 am • ABC/ESPN
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Commanders at 49ers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Commanders
1-2
N/A
N/A
N/A
49ers
3-0
N/A
N/A
N/A
location pinTuesday 12:15 a.m.
October 20, 2026
Levi's StadiumSanta Clara

Commanders vs. 49ers Props

Prop Projections

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Prop Odds Comparison

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Commanders vs. 49ers Public Betting Percentages

Away Logo

Commanders

Public

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
49ers
2-11-1N/A1-11-0
Commanders
2-11-01-1N/A2-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
49ers
2-12-0N/A2-00-1
Commanders
3-01-02-0N/A3-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
49ers
3-0N/AN/A2-01-0
Commanders
1-2N/AN/AN/A1-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 27thARIW 36-30-7.5 LO 48.5SF -400
Sep 20thMIAW 35-13-13 WO 45SF -1000
Sep 11th@LAW 27-7+3.5 WU 47.5SF +166
Aug 28th@LVW 18-12+3.5 WU 37.5SF +139
Aug 21st@LACW 41-17+2.5 WO 44.5SF +132

Commanders vs. 49ers Injury Updates

Commanders Injuries

  • Chig Okonkwo
    TE

    Okonkwo is doubtful with hamstring

    Doubtful

  • Jayden Daniels
    QB

    Daniels is doubtful with elbow

    Doubtful

49ers Injuries

  • Mike Evans
    WR

    Evans is questionable with ribs

    Questionable

  • Demarcus Robinson
    WR

    Robinson is out with ankle

    Out

  • Christian Kirk
    WR

    Kirk is out with calf

    Out

  • Jake Tonges
    TE

    Tonges is out with knee

    Out

  • De'Zhaun Stribling
    WR

    Stribling is out with ankle

    Out

Player Stats
  • passing yards
    Brock Purdy logo
    Brock Purdy
    789
    pyds
  • passing touchdowns
    Brock Purdy logo
    Brock Purdy
    9
    ptd
  • rushing yards
    Christian McCaffrey logo
    Christian McCaffrey
    166
    ryds
  • rushing touchdowns
    Christian McCaffrey logo
    Christian McCaffrey
    3
    rtd
Depth Charts
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Starter2ND3RD4TH
QBBrock PurdyMac JonesKurtis Rourke
RBChristian McCaffreyJordan JamesKaelon BlackSincere McCormick
WRDe'Zhaun StriblingChristian KirkWill Pauling
TEJake TongesLuke FarrellBrayden Willis
LTTrent WilliamsEnrique CruzVederian Lowe
LGCarver WillisBrett Toth
CJake BrendelDrake Nugent
RGDominick PuniConnor ColbyNick Zakelj
RTColton McKivitzAusten PleasantsIsaac Alarcon
LDEKeion White
RDENick BosaSam OkuayinonuRomello HeightOgbo Okoronkwo
WLBDre GreenlawLuke GiffordNick MartinGarret Wallow
MLBFred WarnerTatum BethuneJaden DuggerJalen Graham
LCBRenardo GreenJack Jones
SSMalik MustaphaMarques SigleAshtyn Davis
FSJi'Ayir BrownSiran NealJalen Stroman
RCBDeommodore LenoirEphesians Prysock
PCorliss Waitman
HCorliss Waitman
PRJacob CowingJordan Watkins
KRDeebo SamuelJacob Cowing
LSJon Weeks
LWRMike EvansDemarcus RobinsonKhaDarel Hodge
NBUpton StoutNate Hobbs
KEddy Pineiro
NTAlfred CollinsGracen HaltonSebastian ValdezJames Thompson
DTOsa OdighizuwaC.J. West
RWRDeebo SamuelJordan WatkinsJacob CowingWesley Grimes
FBKyle Juszczyk
Team Stats
546
YDS
789
60/100
Comps/Atts
60/83
5.54
YPA
9.506
7/0
TDs/INTs
9/1
3/8
Sacks/Yards
0/0
396
Rush Yards
409
96
Attempts
80
4.125
YPC
5.113
1
TDs
4
Fumbles Lost
0
Interceptions
1

Efficiency

6/9 66.67%
Redzone
9/10 90%
16/42 0%
3rd Down
17/27 0%
3/3 0%
4th Down
0/0 0%

First Downs

61
Total
69
31
Pass
42
25
Rush
23
5
Penalty
4
/
Penalties/Yards
/
Possession

Commanders vs. 49ers Odds Comparison

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Commanders at 49ers Team Totals

MatchupOverUnder
Commanders
1-2
N/A
N/A
49ers
3-0
N/A
N/A