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Barcelona vs Olympiacos Prediction, Pick, Champions League Odds (October 21)

Barcelona vs Olympiacos Prediction, Pick, Champions League Odds (October 21) article feature image
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Photo by Getty Images. Pictured: Lamine Yamal

Olympiacos (0-1-1) and Barcelona (1-1-0) will face off today at 12:45 p.m. EDT at Estadi Olimpic Lluis Companys in Barcelona, Spain.

Barcelona is favored at a -550 price, with the over/under set at 3.5 (-105o / -130u) goals.

Let's get into my Olympiacos vs. Barcelona prediction.

Olympiacos vs. Barcelona Prediction

Pick: Barcelona -2 Asian Handicap
My Olympiacos vs. Barcelona best bet is on the home team to win by more than two goals.

Playbook

Olympiacos vs. Barcelona Odds

Olympiacos Logo
Tuesday, Oct 21
12:45 p.m. ET
Barcelona Logo
Olympiacos Odds
SpreadTotalMoneyline
+2.5
-165
3.5
-105o / -130u
+1400
Barcelona Odds
SpreadTotalMoneyline
-2.5
+120
3.5
-105o / -130u
-550
Odds via BetMGM. Get up-to-the-minute CHAMPIONS odds here.
BetMGM Logo

Olympiacos vs. Barcelona Pick

Pick: Barcelona -2 Asian Handicap (-135)

Goal difference is key in the league phase of the Champions League. Barcelona has three points after two matches, so this is a golden opportunity for Hansi Flick’s team to strengthen its position. As a result, we are banking on the home side winning emphatically by picking them at -2 on the Asian handicap as part of our Barcelona vs Olympiacos predictions.

The Blaugrana are certainly capable of scoring goals in abundance. Since the start of the 2024/25 campaign, Flick’s team has scored the most goals in the Champions League, with an average of 2.88 per game. In last season’s league phase, all three of Barcelona’s home wins came by a margin of three goals or more. The fourth home game was a 2-2 draw with Atalanta, with qualification already secured.

Barcelona’s strength is in its attacking prowess. The team has been hit by injuries to the forward line in the opening months of the season, but remains a potent threat.

Olympiacos has failed to score in either of its league phase matches thus far. The team's last match was a 2-0 away defeat against Arsenal, but Mikel Arteta’s team was credited with creating seven big chances, and likely should have won by a wider margin.

A two-goal defeat against Barcelona would mean this selection results in getting your money back, but the Catalans have a better attacking record than the Gunners.

Olympiacos vs. Barcelona Projections

Projected Chance of Winning

OlympiacosDrawBarcelona
5.8%11.0%83.2%

Projected Total Goals

OlympiacosTotal GoalsBarcelona
0.573.382.81

Olympiacos vs. Barcelona Betting Analysis

Barcelona welcomes Olympiacos at the Nou Camp for Matchday 3 of the UEFA Champions League, aiming to bounce back from their 2-1 defeat against PSG.

Olympiacos has lost its last 11 Champions League group stage/league phase matches away from home. At the same time, Hansi Flick’s team has won all its previous seven home games against Greek sides and is not expected to falter on Tuesday.

It's no surprise that the odds have the Catalans as heavy favorites with an implied 84.1% probability of a win.

Ahead of the game against Girona, they scored an average of 2.5 goals per competitive match. Moreover, Lamine Yamal should be fit to play, increasing the Blaugrana’s attacking output.

Thirteen of 14 Barcelona matches in last season’s Champions League campaign saw a minimum of three goals, with 11 fixtures witnessing over 3.5. This season, the Spaniards’ first two European games have both ended 2-1.

Olympiacos vs. Barcelona Projected Starting Lineups

Olympiacos

Tzolakis; Costinha, Retsos, Pirola, Ortega; Hezze, D.García; Martins, Chiquinho, Podence; El Kaabi.

Barcelona

Szczesny; Koundé, E.García, Cubarsí, Martin; De Jong, Pedri; Yamal, Olmo, Rashford; Torres.

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