Cardinals vs. Giants Odds & Betting Predictions - September 24, 2025

Cardinals at Giants

1:45 am • FDSMW

St. Louis Cardinals

9

9 - 8

San Francisco Giants

8

pitcher		team	era	w-l
L.Webb			3.30	14-11
A.Pallante			5.31	6-15

MatchupOpenSpreadTotalMoneyline
Cardinals 78-81	+1.5	+1.5-128	o7.5-112	+167
Giants 78-81	u7.5	-1.5+110	u7.5-109	-200

location pin

Wednesday 1:45 a.m.

September 24, 2025

Oracle ParkSan Francisco

Over 7.5-110

1u

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MLB Public Betting

Giants are 2-3 in their last 5 games.
Giants are 2-3 in their last 5 games against the spread
Giants are 41-40 in their road games against the spread
The totals have gone OVER in 3 of Giants' last 5 games
The totals have gone OVER in 34 of Giants' 78 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	74-85	33-45	41-40	33-56	40-28
Cardinals	80-79	41-40	39-39	25-42	54-37

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	74-78-7	34-43-1	40-35-6	35-53-1	37-25-6
Cardinals	79-73-7	39-39-3	40-34-4	33-29-5	45-44-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	78-81	39-39	39-42	46-43	31-37
Cardinals	78-81	44-37	34-44	33-34	44-47

date	opponent	score	spread	over/under	moneyline
Sep 23rd	STL	L 5-6	-1.5 L	O 8	STL -148
Sep 21st	@LAD	W 3-1	+1.5 W	U 9	SF +178
Sep 21st	@LAD	L 5-7	+1.5 L	O 9	LAD +200
Sep 20th	@LAD	L 3-6	+1.5 L	U 9	LAD +160
Sep 19th	@LAD	L 1-2	+1.5 W	U 7.5	LAD +144

Jose Fermin
2B
Jose Fermin scratched Tuesday.
Out
Masyn Winn
SS
Masyn Winn (knee) has been scratched Friday.
Out

Thomas Murphy
C
Murphy is out with back
Out
Jonathan Brubaker
RP
Brubaker is out with ribs
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RA.Pallante, P		66	2.2	4	2
LJ.King, P		17	1	0	0
RJ.Alcala, P		27	1.1	3	2
RC.Roycroft, P		28	2	0	1
RM.Svanson, P		12	1	1	0
LJ.Romero, P		16	0.2	1	0
RR.O'Brien, P		5	0.1	1	0

HITTERS	H-AB	R	HR	RBI
1B.Donovan, 2B	4-5	1	0	1
1J.Fermin, PR	0-0	1	0	0
1J.Fermin, 2B	0-0	1	0	0
2I.Herrera, DH	2-4	2	1	3
3A.Burleson, 1B	2-5	0	0	2
4N.Arenado, 3B	2-5	1	1	1
5L.Nootbaar, LF	2-5	1	0	0
5N.Church, PR	0-0	0	0	0
5N.Church, LF	0-0	0	0	0
6T.Saggese, SS	1-5	0	0	1
7J.Crooks, C	0-4	0	0	0
8J.Walker, RF	1-4	1	0	0
9V.Scott, CF	1-2	2	0	0

PITCHER		PC	IP	K	ER
RL.Webb, P		97	6	5	3
LJ.Lucchesi, P		27	0.2	1	3
RS.Bivens, P		14	0.1	0	1
RJ.Peguero, P		7	1	1	0
RR.Walker, P		27	1	1	2

HITTERS	H-AB	R	HR	RBI
1H.Ramos, LF	2-5	2	1	1
1G.McCray, LF	0-0	0	0	0
2R.Devers, 1B	1-5	0	0	0
3W.Adames, SS	2-5	1	0	1
4M.Chapman, 3B	1-4	1	0	1
5B.Eldridge, DH	0-3	0	0	0
5W.Flores, PH	0-1	0	0	0
6J.Lee, CF	1-4	0	0	1
7P.Bailey, C	2-4	2	0	1
8C.Koss, 2B	1-3	1	0	1
9D.Gilbert, RF	1-4	1	0	0

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MatchupOverUnder
Cardinals 78-81	o3-110	u3-117
Giants 78-81	o4.5+102	u4.5-130