Nationals vs. Mets Odds & Betting Predictions - September 21, 2025

Nationals at Mets

5:40 pm • WPIX

Washington Nationals

3

3 - 2

New York Mets

2

pitcher		team	era	w-l
S.Manaea			5.59	2-4
J.Irvin			5.69	9-13

MatchupOpenSpreadTotalMoneyline
Nationals 64-93	+1.5	+1.5+113	o8.5-118	+235
Mets 80-76	u8.5	-1.5-135	u8.5-101	-290

location pin

Sunday 5:40 p.m.

September 21, 2025

Citi FieldFlushing, Queens

Under 8.5+105

2.1u

NYM -1.5-120

1u

B.Baty o0.5 HR+700

0.25u

P.Alonso o0.5 HR+370

0.25u

Over 8.5-114

1u

Sunday's MLB Best Bets
Action Network Staff•
Sep 21, 2025 UTC

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MLB Public Betting

Mets are 3-2 in their last 5 games.
Mets are 3-2 in their last 5 games against the spread
Mets are 33-43 in their road games against the spread
The totals have gone OVER in 2 of Mets' last 5 games
The totals have gone OVER in 40 of Mets' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Mets	72-85	39-42	33-43	46-65	26-20
Nationals	76-82	32-46	44-36	4-13	71-69

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Mets	74-77-6	40-39-2	34-38-4	53-52-6	21-25
Nationals	79-71-8	38-36-4	41-35-4	6-11	72-60-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Mets	81-76	49-32	32-44	62-49	19-27
Nationals	64-94	31-47	33-47	6-11	57-83

date	opponent	score	spread	over/under	moneyline
Sep 20th	WSH	L 3-5	-1.5 L	U 8.5	WSH -301
Sep 19th	WSH	W 12-6	-	-	-
Sep 18th	SD	W 6-1	-1.5 W	U 9	NYM -143
Sep 17th	SD	L 4-7	-1.5 L	O 7.5	SD -130
Sep 16th	SD	W 8-3	+1.5 W	O 8	NYM -125

Jesse Winker
LF
Winker is out with back
Out
Griffin Canning
SP
Canning is out with achilles
Out
Nick Madrigal
3B
Madrigal is out with shoulder
Out
Tylor Megill
SP
Megill is out with elbow
Out
Christian Scott
SP
Scott is out for season with elbow
Out for Season

Josiah Gray
SP
Josiah Gray (elbow) scratched Tuesday.
Out
DJ Herz
SP
Herz is out with elbow
Out

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PITCHER		PC	IP	K	ER
RJ.Irvin, P		93	5.1	5	2
LM.Parker, P		53	3.2	2	0

HITTERS	H-AB	R	HR	RBI
1J.Wood, DH	1-4	0	0	0
2D.Crews, RF	1-4	0	0	0
3J.Bell, 1B	1-3	0	0	0
3A.Chaparro, PH	0-1	0	0	0
3A.Chaparro, 1B	0-1	0	0	0
4D.Lile, LF	1-1	1	0	0
4R.Hassell, LF	0-3	0	0	0
5P.DeJong, 2B	0-4	0	0	0
6J.Alfaro, C	2-4	1	0	0
7B.House, 3B	0-4	0	0	0
8N.Nunez, SS	2-4	1	1	2
9J.Young, CF	1-3	0	0	0

PITCHER		PC	IP	K	ER
LS.Manaea, P		50	3	3	3
RC.Holmes, P		57	3.2	3	0
LB.Raley, P		5	0.1	1	0
LG.Soto, P		17	1	2	0
RE.Diaz, P		15	1	3	0

HITTERS	H-AB	R	HR	RBI
1F.Lindor, SS	1-4	1	1	1
2J.Soto, RF	1-2	0	0	0
3B.Nimmo, LF	1-4	0	0	0
3B.Nimmo, CF	1-4	0	0	0
4P.Alonso, 1B	2-4	0	0	0
4L.Acuna, PR	0-0	0	0	0
4L.Acuna, 2B	0-0	0	0	0
5J.McNeil, 2B	0-4	0	0	0
5J.McNeil, 1B	0-4	0	0	0
6M.Vientos, DH	0-3	0	0	0
6F.Alvarez, PH	0-1	0	0	0
7B.Baty, 3B	0-4	0	0	0
8L.Torrens, C	1-4	1	0	0
9C.Mullins, CF	1-2	0	0	1
9S.Marte, PH	1-1	0	0	0
9S.Marte, LF	1-1	0	0	0

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MatchupOverUnder
Nationals 64-93	o3-114	u3-113
Mets 80-76	o5.5+106	u5.5-136