Padres vs. Tigers Odds & Betting Predictions - April 21, 2025

Padres at Tigers

10:40 pm • Fox Sports 1
4 - 6
Starting Pitchers
pitcherteameraw-l
Keider Montero logoK.MonteroDetroit Tigers logo5.930-1
Randy Vasquez logoR.VasquezSan Diego Padres logo4.281-3

Padres at Tigers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
17-11
+1.5
+1.5-186
o8.5-107
+116
Tigers
18-10
u8.5
-1.5+142
u8.5-120
-148
location pinMonday 10:40 p.m.
April 21, 2025
Comerica ParkDetroit
Padres vs. Tigers Expert Picks
Kyle Just Bets
Kyle Just Bets
Last 30d: 20-3-0 (+13.0u)
R.Vasquez u3.5 Ks (Live)-128
0.39u
R.Vasquez u15.5 Outs (Live)-135
0.37u
Kyle Murray
Kyle Murray
Last 30d: 102-121-5 (+24.1u)
Z.McKinstry o1.5 Hits + Runs + RBIs-120
1u
R.Greene o1.5 Total Bases+120
1u
The Degenerate
The Degenerate
Last 30d: 107-147-5 (-1.9u)
Over 8.5-105
0.71u
Boomer Betz
Boomer Betz
Last 30d: 161-174-5 (+45.2u)
SD u3.5 Team Total+100
2u
#BQ
Firefighter Bets
Firefighter Bets
Last 30d: 199-207-2 (-5.1u)
F.Tatis o1.5 Total Bases-125
1u
Shady Biev
Shady Biev
Last 30d: 61-86-3 (-10.9u)
SD +122
2u
Picks Office
Picks Office
Last 30d: 88-89-4 (-7.2u)
Under 8.5-115
1u
Padres' last 4 Vasquez starts: 0-4 to the under. ERA at 1.74, zero HRs allowed in 20.2 IP. Not a big strikeout guy, but elite soft contact – 14 hits total. Padres bullpen is dominant: 1.41 ERA, 0.87 WHIP. Suarez & Adam lights out late. SD tough to score on after 6th. Comerica plays big, suppresses runs. Tigers allow just 2.4 runs/game at home – starters holding a 1.61 ERA in Detroit. Montero shaky, but Detroit’s pen (3.04 ERA, 1.07 WHIP) solid at home. Kahnle (1.04 ERA), Holton (1.54) lead strong middle relief group. Quick hook likely. Padres’ road offense dips to 3.33 R/9 vs 4.67 overall. Under is 24-8-3 in Tigers’ last 35 at Comerica. Padres under in 10 of last 16 interleague. Tight matchup, elite pens, low HR park, and a starter in Vasquez who just doesn’t give up big innings.
Cam Is Money
Cam Is Money
Last 30d: 106-114-5 (-8.2u)
SD o1.5 Team Total (F5)-130
0.77u
Lines at Lunch
Lines at Lunch
Last 30d: 63-62-7 (-7.0u)
DET -0.5 (F5)-105
1u
Steak Friend
Steak Friend
Last 30d: 220-255-7 (-21.5u)
DET -142
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 113-127-17 (-5.3u)
DET -0.5 (F5)-104
1u
Billy Ward
Billy Ward
Last 30d: 43-50-0 (-2.7u)
Over 0.5 (1st Inn)-105
1u
Good to -115
Capper Central
Capper Central
Last 30d: 131-88-14 (+29.3u)
Under 8.5-125
1.25u
Mjaybrod
Mjaybrod
Last 30d: 94-79-5 (+12.5u)
DET -130
0.77u
I bet (-123 on PX)
Brian Bitler
Brian Bitler
Last 30d: 84-99-0 (-52.3u)
SD +114
3u
Sean Zerillo
Sean Zerillo
Last 30d: 188-191-17 (-2.0u)
Under 8.5-115
0.58u
Bet to 8 (-105)

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Prop Odds Comparison

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Padres vs. Tigers Public Betting Percentages

Away Logo

Padres

Public

59%

Bets%

41%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Tigers
17-1112-45-79-58-5
Padres
15-1312-43-99-66-7

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Tigers
10-16-24-10-26-64-9-16-6-1
Padres
10-17-14-11-16-65-9-15-8

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Tigers
18-1013-35-711-37-6
Padres
17-1112-45-711-46-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 20thKCL 3-4-1.5 LU 7KC -225
Apr 19thKCW 3-1-1.5 WU 8DET -135
Apr 18thKCW 7-3+1.5 WO 7.5DET +120
Apr 17thKCW 6-1-1.5 WU 7.5DET -155
Apr 16th@MILL 1-5+1.5 LU 8.5MIL +131

Tigers vs. Padres Injury Updates

Tigers Injuries

  • Alex Cobb
    P

    Cobb is out with hip

    Out

  • Manuel Margot
    OF

    Margot is out with knee

    Out

  • Jake Rogers
    C

    Jake Rogers (oblique) has been scratched Tuesday.

    Out

  • Parker Meadows
    OF

    Meadows is out with arm

    Out

  • Wenceel Perez
    OF

    Perez is out with back

    Out

  • Jose Urquidy
    P

    Urquidy is out with arm

    Out

  • Ty Madden
    P

    Madden is out with shoulder

    Out

  • Sawyer Gipson-Long
    P

    Gipson-Long is out with groin

    Out

Padres Injuries

  • Joe Musgrove
    P

    Musgrove is out for season with elbow

    Out for Season

  • Yu Darvish
    P

    Darvish is out with elbow

    Out

  • Matt Waldron
    P

    Waldron is out with hamstring

    Out

  • Jackson Merrill
    OF

    Merrill is out with hamstring

    Out

Padres vs. Tigers Box Score
Padres Player Stats
Projected
PITCHERPCIPKER
Randy Vasquez logoRR.Vasquez, P68216
Logan Gillaspie logoRL.Gillaspie, P462.230
Wandy Peralta logoLW.Peralta, P131.100
Yuki Matsui logoLY.Matsui, P27210
HITTERSH-ABRHRRBI
Fernando Tatis logo1F.Tatis, RF1-5101
Gavin Sheets logo2G.Sheets, 1B2-4111
Manny Machado logo3M.Machado, 3B1-3100
Xander Bogaerts logo4X.Bogaerts, SS1-3000
Tirso Ornelas logo5T.Ornelas, LF0-2001
Connor Joe logo5C.Joe, PH0-2000
Connor Joe logo5C.Joe, LF0-2000
Oscar Gonzalez logo6O.Gonzalez, DH2-4001
Jose Iglesias logo7J.Iglesias, 2B0-3100
Tyler Wade logo8T.Wade, CF0-2000
Martin Maldonado logo9M.Maldonado, C0-3000
Yuli Gurriel logo9Y.Gurriel, PH0-1000
Tigers Player Stats
Projected
PITCHERPCIPKER
Keider Montero logoRK.Montero, P924.133
Brant Hurter logoLB.Hurter, P161.210
Brenan Hanifee logoRB.Hanifee, P26220
Will Vest logoRW.Vest, P10110
HITTERSH-ABRHRRBI
Gleyber Torres logo1G.Torres, 2B3-5102
Zach McKinstry logo2Z.McKinstry, RF3-4101
Riley Greene logo3R.Greene, LF1-4001
Spencer Torkelson logo4S.Torkelson, 1B1-4000
Colt Keith logo5C.Keith, DH1-2001
Justyn-Henry Malloy logo5J.Malloy, PH0-1000
Justyn-Henry Malloy logo5J.Malloy, DH0-1000
Jace Jung logo6J.Jung, 3B0-2100
Javier Baez logo7J.Baez, CF1-3100
Trey Sweeney logo8T.Sweeney, SS0-4100
Tomas Nido logo9T.Nido, C1-3101

Padres vs. Tigers Odds Comparison

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Padres at Tigers Team Totals

MatchupOverUnder
Padres
17-11
o3.5-133
u3.5+101
Tigers
18-10
o4.5+106
u4.5-138