Reds vs. Cubs Odds & Betting Predictions - March 21, 2026

Reds at Cubs

1:05 am

Cincinnati Reds

8

8 - 6

Chicago Cubs

6

pitcher		team	era	w-l
M.Boyd			1.93	0-0
B.Williamson			1.64	1-0

MatchupOpenSpreadTotalMoneyline
Reds 13-14	N/A	N/A	N/A
Cubs 11-16	N/A	N/A	N/A

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Saturday 1:05 a.m.

March 21, 2026

Sloan ParkMesa

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MLB Public Betting

Cubs are 4-1 in their last 5 games.
Cubs are 4-1 in their last 5 games against the spread
Cubs are 39-42 in their road games against the spread
The totals have gone OVER in 4 of Cubs' last 5 games
The totals have gone OVER in 40 of Cubs' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	78-84	39-42	39-42	55-60	22-24
Reds	82-78	40-39	42-39	29-43	53-34

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	74-78-10	40-36-5	34-42-5	52-56-7	22-21-3
Reds	58-91-11	26-45-8	32-46-3	20-47-5	37-44-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	92-70	50-31	42-39	73-42	18-28
Reds	83-79	44-35	38-43	39-33	43-44

date	opponent	score	spread	over/under	moneyline
Mar 18th	@ARI	L 8-16	+1.5 L	O 11	ARI +100
Mar 18th	LAA	W 8-6	-1.5 W	O 11.5	CHC -166
Mar 17th	@CLE	W 5-2	+1.5 W	U 9.5	CHC +100
Mar 15th	LAD	L 8-14	-	-	-
Mar 14th	@COL	L 3-4	-	-	-

Noelvi Marte
RF
Marte is day-to-day with side
Day-to-Day
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out

Justin Steele
SP
Steele is out for season with elbow
Out for Season

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PITCHER		PC	IP	K	ER
LB.Williamson, P		75	5.1	2	1
RT.Antone, P		7	0.2	0	0
RK.Nicolas, P		31	0.2	0	1
RJ. Garcia, P		3	0.1	1	0
LB.Burke, P		22	1	1	3
RZ.Maxwell, P		21	1	1	1

HITTERS	H-AB	R	HR	RBI
1J.Trevino, DH	0-3	1	0	0
1A.Duno, PH	0-1	0	0	0
1A.Duno, DH	0-1	0	0	0
2M.McLain, 2B	2-4	1	1	3
3E.De La Cruz, SS	0-4	0	0	0
3G.Hampson, SS	0-1	0	0	0
4S.Stewart, 1B	2-3	2	0	0
4N.Lowe, 1B	1-2	0	0	0
5E.Suarez, 3B	1-2	1	0	1
6S.Steer, LF	2-3	1	1	2
6W.Benson, LF	0-2	0	0	0
6W.Benson, CF	0-2	0	0	0
7T.Stephenson, C	1-3	1	1	1
7P.Higgins, C	0-2	0	0	0
8N.Marte, RF	0-3	0	0	0
8R.Hinds, RF	1-1	0	0	0
9D.Myers, CF	3-3	1	0	0
9J.Bleday, LF	0-1	0	0	0

PITCHER		PC	IP	K	ER
LM.Boyd, P		87	4.2	5	8
RT.Beede, P		5	0.1	1	0
LM.Boyd, P		87	4.2	5	8
LH.Milner, P		16	1	1	0
RP.Maton, P		16	1	1	0
RH.Harvey, P		26	1	2	0
LC.Thielbar, P		12	1	0	0

HITTERS	H-AB	R	HR	RBI
1P.Crow-Armstrong, CF	0-3	0	0	0
1P.Ramirez, 3B	1-2	1	0	1
2A.Bregman, 3B	1-3	0	0	0
2K.Snell, LF	1-1	0	0	1
3I.Happ, LF	1-3	0	0	0
4D.Swanson, SS	1-3	0	0	0
5C.Kelly, 1B	0-2	0	0	0
5C. Trice, CF	0-1	0	0	0
6M.Ballesteros, C	0-2	0	0	0
7M.Shaw, RF	0-2	0	0	0
7C.Bethancourt, C	1-1	1	0	1
8J.Triantos, DH	2-3	1	1	2
9J. Rojas, 2B	2-4	1	1	1

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MatchupOverUnder
Reds 13-14	N/A	N/A
Cubs 11-16	N/A	N/A