Blue Jays vs. Orioles Odds & Betting Predictions - September 22, 2026
Blue Jays at Orioles
10:35 pm • SNETStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
 |  | 4.64 | 8-5 | |
 |  | 6.07 | 3-8 |
Blue Jays at Orioles Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Blue Jays 77-80 | +1.5 | +1.5-215 | o7.5-112 | +102 |
Orioles 76-81 | u7.5 | -1.5+181 | u7.5-107 | -121 |
Oriole Park at Camden YardsBaltimore
Blue Jays vs. Orioles Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Blue Jays vs. Orioles Public Betting Percentages
Betting Trends
- Orioles are 2-3 in their last 5 games.
- Orioles are 4-1 in their last 5 games against the spread
- Orioles are 40-38 in their road games against the spread
- The totals have gone OVER in 1 of Orioles' last 5 games
- The totals have gone OVER in 35 of Orioles' 79 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Orioles vs. Blue Jays Injury Updates
Orioles Injuries
- Jordan Westburg3B
Westburg is out with elbow
Out
Blue Jays Injuries
- Jose BerriosSP
Berrios is out with elbow
Out
- Anthony SantanderRF
Santander is out with shoulder
Out
- Bowden FrancisSP
Francis is out with shoulder
Out
- Addison BargerRF
Addison Barger (elbow) scratched Sunday.
Out
Blue Jays vs. Orioles Odds Comparison
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Blue Jays at Orioles Team Totals
MatchupOverUnder | ||
|---|---|---|
Blue Jays 77-80 | N/A | N/A |
Orioles 76-81 | N/A | N/A |