White Sox vs. Reds Odds & Betting Predictions - March 22, 2026

White Sox at Reds

1:05 am

Chicago White Sox

@

Cincinnati Reds

pitcher		team	era	w-l
A.Abbott			0.00	0-0

MatchupOpenSpreadTotalMoneyline
White Sox 15-13	N/A	N/A	+114
Reds 13-14	N/A	N/A	-135

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Sunday 1:05 a.m.

March 22, 2026

Goodyear BallparkGoodyear

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98°Fahrenheit

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MLB Public Betting

Reds are 3-2 in their last 5 games.
Reds are 2-3 in their last 5 games against the spread
Reds are 42-39 in their road games against the spread
The totals have gone OVER in 1 of Reds' last 5 games
The totals have gone OVER in 26 of Reds' 79 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Reds	82-78	40-39	42-39	29-43	53-34
White Sox	94-68	47-34	47-34	0-2	92-66

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Reds	58-91-11	26-45-8	32-46-3	20-47-5	37-44-6
White Sox	75-80-7	42-34-5	33-46-2	0-2	73-78-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Reds	83-79	44-35	38-43	39-33	43-44
White Sox	60-102	33-48	27-54	1-1	58-100

date	opponent	score	spread	over/under	moneyline
Mar 21st	@CHC	W 8-6	-	-	-
Mar 18th	@LAA	L 4-7	-	-	-
Mar 18th	COL	L 6-8	-	-	-
Mar 18th	CLE	L 6-8	-1.5 L	O 11.5	CLE -135
Mar 16th	@ARI	L 6-11	-1.5 L	O 10.5	ARI -115

Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

Noelvi Marte
RF
Marte is day-to-day with side
Day-to-Day
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out

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MatchupOverUnder
White Sox 15-13	N/A	N/A
Reds 13-14	N/A	N/A