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Duke vs. Clemson Odds & Betting Predictions - November 1, 2025

Duke at Clemson

4:00 pm • ACC Network

Duke Blue Devils

0-0
46
46 - 45

Clemson Tigers

0-0
45

Duke at Clemson Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Duke
0-0
+2.5
+4-110
o54.5-115
+155
Clemson
0-0
u53.5
-4-110
u54.5-115
-188
location pinSaturday 4:00 p.m.
November 01, 2025
Memorial Stadium (Clemson, SC)Clemson
Duke vs. Clemson Expert Picks
The Propfessor
The Propfessor
Last 30d: 17-37-0 (-1.1u)
A.Williams o4.5 Recs-145
0.69u
Brian Bitler
Brian Bitler
Last 30d: 53-69-0 (-44.9u)
DUKE +3.5-105
2.86u
Dan Gaspar
Dan Gaspar
Last 30d: 15-44-1 (-12.2u)
Q.Brown o44.5 Rec Yds-114
1u
Jeremiah Rose
Jeremiah Rose
Last 30d: 13-18-0 (-0.6u)
DUKE +4-110
0.36u
Boomer’s Book
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 1-0-0 (+2.6u)
CLEM -2.5-136
0.6u

Duke vs. Clemson Previews & Analysis

  • Duke vs Clemson PRO System Pick article feature image

    Duke vs Clemson PRO System Pick

    Tanner McGrath•
    Nov 1, 2025 UTC
  • Your Week 10 NCAAF Betting Cheat Sheet article feature image

    Your Week 10 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Nov 1, 2025 UTC
  • Our NCAAF Best Bets for Saturday's Noon Slate article feature image

    Our NCAAF Best Bets for Saturday's Noon Slate

    Action Network Staff•
    Oct 31, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Duke vs. Clemson Public Betting Percentages

Away Logo

Duke

Public

Home Logo

Clemson

60%

Bets%

40%

Money%

NCAAF Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Clemson		N/AN/AN/AN/AN/A
Duke		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Clemson		N/AN/AN/AN/AN/A
Duke		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Clemson		N/AN/AN/AN/AN/A
Duke		N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 18thSMUL 24-35-3.5 LO 49.5SMU -180
Oct 11th@BCW 41-10-14 WU 54.5CLEM -590
Oct 4th@UNCW 38-10-15.5 WO 47.5CLEM -720
Sep 20thSYRL 21-34-17.5 LO 53.5SYR -900
Sep 13th@GTL 21-24-3 LU 50.5GT -145
Team Stats

Total

439
Total Yards
560
64
Total Plays
72
6.859375
Yards Per Play
7.777777777777778

Passing

361
YDS
385
27/42
Comps/Atts
27/36
8.595238095238095
YPA
10.694444444444445
4/0
TDs/INTs
2/0
2/15
Sacks/Yards
1/6

Rushing

78
Rush Yards
175
22
Attempts
36
3.5454545454545454
YPC
4.861111111111111
1
TDs
4

Turnovers

0
Fumbles Lost
1
0
Interceptions
0

Efficiency

4/4 100%
Redzone
6/6 100%
3/14 0%
3rd Down
3/10 0%
5/5 0%
4th Down
3/3 0%

First Downs

22
Total
28
14
Pass
15
4
Rush
11
4
Penalty
2

Misc

9/62
Penalties/Yards
8/87

Duke vs. Clemson Odds Comparison

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Duke at Clemson Team Totals

MatchupOverUnder
Duke
0-0
N/A
N/A
Clemson
0-0
N/A
N/A