Duke vs. Clemson Odds & Betting Predictions - November 1, 2025

Duke at Clemson

4:00 pm • ACC Network

Duke Blue Devils

@

Clemson Tigers

MatchupOpenSpreadTotalMoneyline
Duke 4-3	+2.5	+3.5-114	o53.5-110	+123
Clemson 3-4	u53.5	-3.5-107	u53.5-110	-147

location pin

Saturday 4:00 p.m.

November 01, 2025

Memorial Stadium (Clemson, SC)Clemson

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55°Fahrenheit

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0%Rain

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5Wind

No props found

NCAAF Public Betting

Clemson are 2-3 in their last 5 games.
Clemson are 1-4 in their last 5 games against the spread
Clemson are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Clemson' last 5 games
The totals have gone OVER in 2 of Clemson' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson	2-5	0-4	2-1	2-5	N/A
Duke	3-4	1-3	2-1	3-2	0-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson	3-4	2-2	1-2	3-4	N/A
Duke	5-2	3-1	2-1	3-2	2-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson	3-4	N/A	N/A	3-4	N/A
Duke	4-3	N/A	N/A	4-1	0-2

date	opponent	score	spread	over/under	moneyline
Oct 18th	SMU	L 24-35	-3.5 L	O 49.5	SMU -180
Oct 11th	@BC	W 41-10	-14 W	U 54.5	CLEM -590
Oct 4th	@UNC	W 38-10	-15.5 W	O 47.5	CLEM -720
Sep 20th	SYR	L 21-34	-17.5 L	O 53.5	SYR -900
Sep 13th	@GT	L 21-24	-3 L	U 50.5	GT -145

Total

Passing

2233

YDS

1990

177/254

Comps/Atts

171/263

8.79

YPA

7.57

17/2

TDs/INTs

15/6

14/88

Sacks/Yards

11/69

Rushing

1010

Rush Yards

815

214

Attempts

212

4.72

YPC

3.84

12

TDs

8

Turnovers

Fumbles Lost

2

Interceptions

6

Efficiency

24/31 77.4%

Redzone

16/20 80%

38/84 0%

3rd Down

36/93 0%

8/12 0%

4th Down

11/21 0%

First Downs

166

Total

147

101

Pass

89

52

Rush

47

13

Penalty

11

Misc

/

Penalties/Yards

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See more NCAAF Odds

MatchupOverUnder
Duke 4-3	N/A	N/A
Clemson 3-4	N/A	N/A