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SMU vs. Clemson Odds & Betting Predictions - October 18, 2025

SMU at Clemson

7:30 pm • ACC Network

SMU Mustangs

4-1
35
35 - 24

Clemson Tigers

3-2
24

SMU at Clemson Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
SMU
4-1
+11.5
+3.5-110
o49.5-112
+146
Clemson
3-2
u55.5
-3.5-110
u49.5-110
-180
location pinSaturday 7:30 p.m.
October 18, 2025
Memorial Stadium (Clemson, SC)Clemson
SMU vs. Clemson Expert Picks
Picks Office
Picks Office
Last 30d: 0-0-0 (+0.0u)
SMU +4.5-105
0.95u
X: PicksOffice
YBK Picks.com
Last 30d: 45-41-0 (+3.2u)
SMU +3.5-105
2.86u
Action Analytics
Action Analytics
Last 30d: 5-12-0 (-9.4u)
Over 50.5-110
1u
Collin Wilson
Collin Wilson
Last 30d: 77-57-1 (+11.7u)
CLEM u29 Team Total-111
0.5u
SMU +7-110
1u
Kody Malstrom
Kody Malstrom
Last 30d: 63-54-2 (+1.2u)
SMU +10-115
0.5u
Doug Ziefel
Doug Ziefel
Last 30d: 328-384-9 (+7.5u)
CLEM -5.5 (1H)-110
0.55u
Tyler Shoemaker
Tyler Shoemaker
Last 30d: 81-105-1 (-17.8u)
Under 55.5-110
5.5u
Babs .
Babs .
Last 30d: 59-51-1 (+1.7u)
CLEM -8.5-110
1u

SMU vs. Clemson Previews & Analysis

  • SMU vs. Clemson: A Bit of Value on Road 'Dog article feature image

    SMU vs. Clemson: A Bit of Value on Road 'Dog

    Action Network Staff•
    Oct 18, 2025 UTC
  • Our CFB Best Bets For Saturday Afternoon article feature image

    Our CFB Best Bets For Saturday Afternoon

    Action Network Staff•
    Oct 18, 2025 UTC
  • Your Week 8 NCAAF Betting Cheat Sheet article feature image

    Your Week 8 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Oct 18, 2025 UTC
  • Collin Wilson's Week 8 ML Round Robin article feature image

    Collin Wilson's Week 8 ML Round Robin

    Collin Wilson•
    Oct 17, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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SMU vs. Clemson Public Betting Percentages

Away Logo

SMU

Public

Home Logo

Clemson

57%

Bets%

43%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Clemson are 3-2 in their last 5 games.
  • Clemson are 2-3 in their last 5 games against the spread
  • Clemson are 1-1 in their road games against the spread
  • The totals have gone OVER in 3 of Clemson' last 5 games
  • The totals have gone OVER in 2 of Clemson' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Clemson		2-31-21-12-10-2
SMU		1-3-11-20-1-11-2-10-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Clemson		3-22-11-11-22-0
SMU		2-31-21-11-31-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Clemson		3-2N/AN/A3-00-2
SMU		4-1N/AN/A4-00-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 11th@BCW 41-10-14 WU 54.5CLEM -590
Oct 4th@UNCW 38-10-15.5 WO 47.5CLEM -720
Sep 20thSYRL 21-34-17.5 LO 53.5SYR -900
Sep 13th@GTL 21-24-3 LU 50.5GT -145
Sep 6thTROYW 27-16-30.5 LU 51.5CLEM -11946
Team Stats

Total

429
Total Yards
352
71
Total Plays
72
6.042253521126761
Yards Per Play
4.888888888888889

Passing

290
YDS
317
23/43
Comps/Atts
29/42
6.744186046511628
YPA
7.5476190476190474
2/1
TDs/INTs
3/0
1/5
Sacks/Yards
4/17

Rushing

139
Rush Yards
35
28
Attempts
30
4.964285714285714
YPC
1.1666666666666667
2
TDs
0

Turnovers

0
Fumbles Lost
1
1
Interceptions
0

Efficiency

3/3 100%
Redzone
2/2 100%
7/17 0%
3rd Down
8/19 0%
0/0 0%
4th Down
1/2 0%

First Downs

21
Total
20
12
Pass
16
8
Rush
2
1
Penalty
2

Misc

5/60
Penalties/Yards
2/9

SMU vs. Clemson Odds Comparison

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SMU at Clemson Team Totals

MatchupOverUnder
SMU
4-1
N/A
N/A
Clemson
3-2
N/A
N/A