The Michigan Wolverines take on the Nebraska Cornhuskers in Lincoln, Nebraska. Kickoff is set for 3:30 p.m. EDT on CBS.
Michigan is favored by one point on the spread with a moneyline of -120. The total is set at 47.5 points.
Here’s my Michigan vs. Nebraska prediction and college football picks for Saturday, September 20, 2025.
Michigan vs Nebraska Odds
| Michigan Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1 -110 | 47.5 -110o / -110u | -120 |
| Nebraska Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1 -110 | 47.5 -110o / -110u | +100 |
- Michigan vs Nebraska point spread: Michigan -1 (-110), Nebraska +1 (-110)
- Michigan vs Nebraska over/under: 47.5 (-110o / -110u)
- Michigan vs Nebraska moneyline: Michigan -120, Nebraska +100
Michigan vs Nebraska Picks, Parlay
- Nebraska/Michigan Under 47.5
- Bryce Underwood 150+ Passing Yards
Parlay Odds: +230 (bet365)
Under 47.5
The Wolverines and Cornhuskers clash for a highly anticipated matchup on Saturday afternoon.
Nebraska aims to snap a 0-27 streak against top 25 teams. The Cornhuskers have not beaten a top-25 team since 2016.
The pace of this contest will bode well for the Under.
Bryce Underwood is a highly talented true freshman, but he will likely struggle against the experienced Cornhuskers' defense on the road, given the challenging environment.
Nebraska has been inconsistent early in the season on the offensive side of the football. While I do like the Cornhuskers to win at home, Michigan's defense will likely slow down this Nebraska offensive attack.
I expect a tightly contested, low-scoring Big Ten affair on Saturday.
Bryce Underwood 150+ Passing Yards
As mentioned, Underwood will be tested in this road environment, but we are not asking much of Underwood with this prop.
I expect Michigan to struggle running the football, forcing them to lean on their passing game.
There is a strong chance Michigan will play most of the game from behind, which will bode well for this prop.
Underwood has cashed this prop in two of his three games this year.
The sole game Underwood did not cash was when he landed on 142 yards against Oklahoma.
Michigan vs Nebraska Same-Game Parlay
- Nebraska/Michigan Under 47.5
- Bryce Underwood 150+ Passing Yards
Parlay Odds: +230 (bet365)
