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49ers vs. Cardinals Odds & Betting Predictions - January 5, 2025

49ers at Cardinals

9:25 pm • FOX

San Francisco 49ers

3-1
24
24 - 47

Arizona Cardinals

2-2
47

49ers at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
49ers
3-1
-2.5
+5.5-118
o43.5-102
+195
Cardinals
2-2
u46.5
-5.5-102
u43.5-118
-240
location pinSunday 9:25 p.m.
January 05, 2025
State Farm StadiumGlendale
49ers vs. Cardinals Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 70-105-3 (-19.3u)
K.Murray o222.5 Pass Yds-112
1u
Sir Lockselot
Sir Lockselot
Last 30d: 32-57-0 (-12.5u)
SF +190
2u
🔑 Niners ML +190 (FanDuel) 2u I really don’t think the Cardinals should ever be this big of favorites. 2 teams playing for pride, still a division rival, Dobbs can get it done. The Niners aren’t gonna go out sorry, I think they end this season with a W.
Scott Rickenbach
Scott Rickenbach
Last 30d: 48-44-2 (-3.6u)
SF +4.5-106
1u
Player Prop Savant
Player Prop Savant
Last 30d: 32-22-0 (+6.8u)
M.Carter o59.5 Rush Yds-110
1.1u
Nick Giffen
Nick Giffen
Last 30d: 47-119-1 (+10.5u)
Over 20.5 (1H)-110
0.45u
Convince Me
Convince Me
Last 30d: 0-0-0 (+0.0u)
Over 20.5 (1H)-110
0.91u
@nick_giffen
J.Dobbs o26.5 Rush Yds-115
1u
@SimonHunterNFL
Mjaybrod
Mjaybrod
Last 30d: 68-85-3 (-11.6u)
K.Murray o224.5 Pass Yds-110
0.91u
400 yards away from 4K
Matt DiLeo
Matt DiLeo
Last 30d: 45-29-0 (+8.5u)
K.Murray u1.5 Pass TDs-125
1u
Cam Is Money
Cam Is Money
Last 30d: 53-69-3 (-14.8u)
M.Harrison u55.5 Rec Yds-115
1u
Jeremiah Rose
Jeremiah Rose
Last 30d: 34-40-1 (-2.7u)
K.Murray Anytime TD Scorer Yes+140
0.6u
Resorts World
The Propfessor
The Propfessor
Last 30d: 34-56-2 (+1.2u)
J.Jennings o68.5 Rec Yds-115
1.15u
Needs 77 for 1k receiving. Shanahan said that they aren��t playing after next week, so he’d like to get the guys their milestones/incentives.

49ers vs. Cardinals Previews & Analysis

  • Early Wild Card Weekend Bets & Week 18 Recap with Chad Millman & Simon Hunter | Favorites Podcast article feature image

    Early Wild Card Weekend Bets & Week 18 Recap with Chad Millman & Simon Hunter | Favorites Podcast

    Simon Hunter•
    Jan 5, 2025 UTC
  • Gallant's Week 18 ATD Picks & Game Previews article feature image

    Gallant's Week 18 ATD Picks & Game Previews

    Gilles Gallant•
    Jan 5, 2025 UTC
  • 2024 NFL Week 18 NFL PLAYER PROPS & BETTING PICKS! | NFL Picks & Predictions | Power Hour article feature image

    2024 NFL Week 18 NFL PLAYER PROPS & BETTING PICKS! | NFL Picks & Predictions | Power Hour

    Gilles Gallant•
    Jan 5, 2025 UTC
  • 49ers vs. Cardinals: Target 1st Half Total article feature image

    49ers vs. Cardinals: Target 1st Half Total

    Nick Giffen•
    Jan 5, 2025 UTC
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49ers vs. Cardinals Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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49ers vs. Cardinals Public Betting Percentages

Away Logo

49ers

Public

Home Logo

Cardinals

59%

Bets%

41%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cardinals are 2-2 in their last 5 games.
  • Cardinals are 2-2 in their last 5 games against the spread
  • Cardinals are 2-0 in their road games against the spread
  • The totals have gone OVER in 1 of Cardinals' last 4 games
  • The totals have gone OVER in 1 of Cardinals' 2 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		2-20-22-01-11-1
49ers		2-20-22-02-2N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		1-31-10-21-10-2
49ers		2-21-11-12-2N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		2-2N/AN/A2-00-2
49ers		3-1N/AN/A3-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 29th@LAL 9-13+6.5 WU 48LA +245
Dec 22nd@CARL 30-36-5.5 LO 47CAR -245
Dec 15thNEW 30-17-6 WO 46.5ARI -264
Dec 8thSEAL 18-30-3 LO 45.5SEA -177
Dec 1st@MINL 22-23+3.5 WU 45.5MIN +146

49ers vs. Cardinals Injury Updates

49ers Injuries

  • George Kittle
    TE

    Kittle is out with hamstring

    Out

  • Brandon Aiyuk
    WR

    Aiyuk is out with knee

    Out

  • Jauan Jennings
    WR

    Jennings is questionable with ankle

    Questionable

  • Brock Purdy
    QB

    Purdy is questionable with toe

    Questionable

  • Ricky Pearsall
    WR

    Pearsall is questionable with knee

    Questionable

  • Jacob Cowing
    WR

    Cowing is out with hamstring

    Out

  • Jordan Watkins
    WR

    Watkins is doubtful with ankle

    Doubtful

  • Jordan James
    RB

    James is doubtful with finger

    Doubtful

Cardinals Injuries

  • Zay Jones
    WR

    Jones is questionable with concussion

    Questionable

  • James Conner
    RB

    Conner is out with foot

    Out

  • Will Hernandez
    OL

    Hernandez is out with knee

    Out

  • Owen Pappoe
    LB

    Pappoe is questionable with quad

    Questionable

  • Dante Stills
    DE

    Stills is questionable with heel

    Questionable

See more NFL Injuries Right Arrow
Team Stats

Total

436
Total Yards
393
73
Total Plays
62
6
Yards Per Play
6.3

Passing

326
YDS
242
29/43
Comps/Atts
25/35
6.622
YPA
6.914
2/2
TDs/INTs
4/0
2/28
Sacks/Yards
0/0

Rushing

138
Rush Yards
151
28
Attempts
27
4.929
YPC
5.593
1
TDs
2

Turnovers

1
Fumbles Lost
0
2
Interceptions
0

Efficiency

2/2 100%
Redzone
4/4 100%
5/13 0%
3rd Down
4/11 0%
1/2 0%
4th Down
2/2 0%

First Downs

26
Total
26
16
Pass
14
9
Rush
8
1
Penalty
4

Misc

13/85
Penalties/Yards
1/5
31:51
Possession
28:09

49ers vs. Cardinals Odds Comparison

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49ers at Cardinals Team Totals

MatchupOverUnder
49ers
3-1
o18.5-118
u18.5-102
Cardinals
2-2
o23.5-115
u23.5-105