49ers vs. Cardinals Odds & Betting Predictions - January 5, 2025
49ers at Cardinals
9:25 pm • FOX49ers at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() 49ers 0-0 | -2.5 | +5.5-118 | o43.5-102 | +195 |
![]() Cardinals 0-0 | u46.5 | -5.5-102 | u43.5-118 | -240 |

State Farm StadiumGlendale
49ers vs. Cardinals Expert Picks

Sandy Plashkes
Last 30d: 83-83-2 (+10.8u)
K.Murray o222.5 Pass Yds-112
1u

Sir Lockselot
Last 30d: 31-64-0 (-39.2u)
SF +190
2u
🔑 Niners ML +190 (FanDuel) 2u
I really don’t think the Cardinals should ever be this big of favorites. 2 teams playing for pride, still a division rival, Dobbs can get it done. The Niners aren’t gonna go out sorry, I think they end this season with a W.

Top Shelf Action 🥃
Last 30d: 152-159-8 (-21.6u)
T.McBride u6.5 Recs+110
0.4u
3.39% ev
Scott Rickenbach
Last 30d: 74-75-4 (-13.9u)
SF +4.5-106
1u

Player Prop Savant
Last 30d: 24-21-1 (+2.7u)
M.Carter o59.5 Rush Yds-110
1.1u

The Touchdown Show
Last 30d: 0-0-0 (+0.0u)
J.Dobbs Anytime TD Scorer Yes+330
3.3u
@TheBMatt

Convince Me
Last 30d: 0-0-0 (+0.0u)
Over 20.5 (1H)-110
0.91u
@nick_giffen
J.Dobbs o26.5 Rush Yds-115
1u
@SimonHunterNFL

Nick Giffen
Last 30d: 16-32-0 (+17.2u)
Over 20.5 (1H)-110
0.45u

Mjaybrod
Last 30d: 0-0-0 (+0.0u)
K.Murray o224.5 Pass Yds-110
0.91u
400 yards away from 4K

Cam Is Money
Last 30d: 106-131-1 (-12.0u)
M.Harrison u55.5 Rec Yds-115
1u

Jeremiah Rose
Last 30d: 7-17-0 (+0.0u)
K.Murray Anytime TD Scorer Yes+140
0.6u
Resorts World

The Propfessor
Last 30d: 21-31-0 (+7.0u)
J.Jennings o68.5 Rec Yds-115
1.15u
Needs 77 for 1k receiving. Shanahan said that they aren’t playing after next week, so he’d like to get the guys their milestones/incentives.
49ers vs. Cardinals Previews & Analysis
49ers vs. Cardinals Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
49ers vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 4-1 in their last 5 games.
- Cardinals are 5-0 in their last 5 games against the spread
- Cardinals are 5-3 in their road games against the spread
- The totals have gone OVER in 1 of Cardinals' last 5 games
- The totals have gone OVER in 5 of Cardinals' 9 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
49ers vs. Cardinals Odds Comparison
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49ers at Cardinals Team Totals
MatchupOverUnder | ||
---|---|---|
![]() 49ers 0-0 | o18.5-118 | u18.5-102 |
![]() Cardinals 0-0 | o23.5-115 | u23.5-105 |