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49ers vs. Falcons Odds & Betting Predictions - October 25, 2026

49ers at Falcons

5:00 pm • FOX

San Francisco 49ers

4-0
@

Atlanta Falcons

2-2

49ers at Falcons Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
49ers
4-0
N/A
N/A
N/A
Falcons
2-2
N/A
N/A
N/A
location pinSunday 5:00 p.m.
October 25, 2026
Mercedes-Benz StadiumAtlanta

49ers vs. Falcons Props

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49ers vs. Falcons Public Betting Percentages

Away Logo

49ers

Public

Home Logo

Falcons

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Falcons are 2-2 in their last 5 games.
  • Falcons are 2-2 in their last 5 games against the spread
  • Falcons are 2-1 in their road games against the spread
  • The totals have gone OVER in 2 of Falcons' last 4 games
  • The totals have gone OVER in 0 of Falcons' 1 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Falcons		2-20-12-1N/A2-2
49ers		3-12-1N/A2-11-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Falcons		2-20-12-1N/A2-2
49ers		2-22-1N/A2-10-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Falcons		2-2N/AN/AN/A2-2
49ers		4-0N/AN/A3-01-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 6th@NOW 45-24+1.5 WO 47.5ATL -105
Sep 25th@GBW 35-14+4.5 WO 43.5ATL +205
Sep 20thCARL 3-34+2.5 LU 43.5CAR +120
Sep 13th@PITL 13-20+6.5 LU 40.5PIT +250
Aug 28th@MIAW 17-12-6 LU 35.5ATL -270

Falcons vs. 49ers Injury Updates

Falcons Injuries

    49ers Injuries

    • Kyle Juszczyk
      FB

      Juszczyk is out with knee

      Out

    • Demarcus Robinson
      WR

      Robinson is out with ankle

      Out

    • Christian Kirk
      WR

      Kirk is out with calf

      Out

    • Jake Tonges
      TE

      Tonges is out with knee

      Out

    • De'Zhaun Stribling
      WR

      Stribling is out with ankle

      Out

    See more NFL Injuries Right Arrow
    Player Stats
    • passing yards
      Michael Penix logo
      Michael Penix
      479
      pyds
    • passing touchdowns
      Michael Penix logo
      Michael Penix
      2
      ptd
    • rushing yards
      Bijan Robinson logo
      Bijan Robinson
      494
      ryds
    • rushing touchdowns
      Brian Robinson logo
      Brian Robinson
      4
      rtd
    Depth Charts
    Right Arrow
    Starter2ND3RD4TH
    QBMichael PenixTua TagovailoaJack StrandCooper Rush
    RBBijan RobinsonBrian Robinson
    WROlamide ZaccheausZachariah BranchVinny Anthony
    TEKyle PittsCharlie WoernerAustin HooperJack Velling
    LTJake MatthewsRiley Mahlman
    LGMatthew BergeronKyle HintonKam Dewberry
    CRyan NeuzilCorey Levin
    RGChris Lindstrom
    RTJawaan TaylorEthan OnianwaMichael Jerrell
    LDEZach Harrison
    LCBMike HughesAvieon TerrellC.J. HendersonMike Ford
    SSJessie BatesDeMarcco Hellams
    FSXavier WattsJammie Robinson
    RCBA.J. TerrellMalcolm DeWalt
    PJake Bailey
    HJake Bailey
    PRZachariah BranchOlamide Zaccheaus
    KRZachariah BranchVinny Anthony
    LSLiam McCullough
    LILBChristian HarrisKendal DanielsJD BertrandJosh Woods
    ROLBZa'Darius SmithCameron ThomasBralen Trice
    DTBrandon DorlusDa'Shawn Hand
    NTMaason SmithLaCale London
    LWRDrake LondonChris BlairAntwane WellsBeaux Collins
    LOLBSamson Ebukam
    RWRJahan DotsonDylan Drummond
    KNick Folk
    RILBDivine DeabloHarold Perkins
    NBSydney BrownDarnay Holmes
    Team Stats

    Passing

    1007
    YDS
    718
    79/113
    Comps/Atts
    63/99
    8.912
    YPA
    7.747
    11/1
    TDs/INTs
    3/6
    0/0
    Sacks/Yards
    8/49

    Rushing

    549
    Rush Yards
    724
    115
    Attempts
    139
    4.774
    YPC
    5.209
    5
    TDs
    8

    Turnovers

    Fumbles Lost
    1
    Interceptions
    6

    Efficiency

    11/13 84.62%
    Redzone
    8/10 80%
    23/40 0%
    3rd Down
    16/43 0%
    1/2 0%
    4th Down
    1/2 0%

    First Downs

    89
    Total
    82
    50
    Pass
    31
    34
    Rush
    44
    5
    Penalty
    7

    Misc

    /
    Penalties/Yards
    /
    Possession

    49ers vs. Falcons Odds Comparison

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    49ers at Falcons Team Totals

    MatchupOverUnder
    49ers
    4-0
    N/A
    N/A
    Falcons
    2-2
    N/A
    N/A