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Panthers vs. Bills Odds & Betting Predictions - August 15, 2026

Panthers at Bills

5:00 pm • NFL+

Carolina Panthers

1-0
@

Buffalo Bills

0-0

Panthers at Bills Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Panthers
1-0
+1.5
+3-115
o38.5-116
+132
Bills
0-0
u37.5
-3-105
u38.5-110
-162
location pinSaturday 5:00 p.m.
August 15, 2026

Panthers vs. Bills Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Panthers vs. Bills Public Betting Percentages

Away Logo

Panthers

Public

Home Logo

Bills

34%

Bets%

66%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Bills		N/AN/AN/AN/AN/A
Panthers		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Bills		N/AN/AN/AN/AN/A
Panthers		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Bills		N/AN/AN/AN/AN/A
Panthers		N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 17th@DENL 30-33+1.5 LO 45.5DEN +105
Jan 11th@JACW 27-24+1.5 WU 51.5BUF +105
Jan 4thNYJW 35-8-13.5 WO 39.5BUF -850
Dec 28thPHIL 12-13-3 LU 45PHI -175
Dec 21st@CLEW 23-20-10.5 LO 41.5BUF -582

Bills vs. Panthers Injury Updates

Bills Injuries

    Panthers Injuries

    • Darren Waller
      TE

      Waller is out with groin

      Out

    See more NFL Injuries Right Arrow
    Player Stats
    • passing yards
      Josh Allen logo
      Josh Allen
      3668
      pyds
    • passing touchdowns
      Josh Allen logo
      Josh Allen
      25
      ptd
    • rushing yards
      James Cook logo
      James Cook
      1621
      ryds
    • rushing touchdowns
      Josh Allen logo
      Josh Allen
      14
      rtd
    Depth Charts
    Right Arrow
    Starter2ND3RD4TH
    QBJosh AllenMitchell TrubiskyShane Buechele
    RBJames CookRay DavisTy JohnsonFrank Gore
    WRKhalil ShakirStephen Gosnell
    TEDalton KincaidDawson KnoxJackson HawesKeleki Latu
    LTDion DawkinsTylan GrableChase LundtTravis Clayton
    LGDavid Edwards
    CConnor McGovernSedrick Van Pran-Granger
    RGO'Cyrus TorrenceAlec Anderson
    RTSpencer BrownRyan Van Demark
    LDEGreg RousseauLandon JacksonJavon Solomon
    WLBMatt MilanoDorian WilliamsKeonta Jenkins
    MLBTerrel BernardJoe AndreessenShaq ThompsonJimmy Ciarlo
    LCBChristian BenfordMaxwell HairstonDorian Strong
    SSCole BishopCam LewisWande Owens
    FSTaylor RappDamar HamlinJordan Hancock
    RCBTre'Davious WhiteDane Jackson
    LSReid Ferguson
    LWRJoshua PalmerTyrell Shavers
    DTEd OliverT.J. SandersDeWayne Carter
    NTDaQuan JonesDeone WalkerZion Logue
    RWRKeon ColemanCurtis Samuel
    FBReggie Gilliam
    NBTaron Johnson
    KTyler Bass

    Panthers vs. Bills Odds Comparison

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    Panthers at Bills Team Totals

    MatchupOverUnder
    Panthers
    1-0
    N/A
    N/A
    Bills
    0-0
    N/A
    N/A