Eagles vs. Bills Odds & Betting Predictions - December 28, 2025

Eagles at Bills

9:25 pm • FOX
13 - 12

Eagles at Bills Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Eagles
2-1
+1.5
+3+100
o45-110
+145
Bills
3-0
u46.5
-3-110
u45-110
-175
location pinSunday 9:25 p.m.
December 28, 2025
Highmark StadiumOrchard Park
Eagles vs. Bills Expert Picks
Jeremiah Rose
Jeremiah Rose
Last 30d: 48-42-0 (-3.0u)
J.Allen Anytime TD Scorer Yes (Live)+220
0.44u
Boyd / FanDuel
Stuck 🚨
Stuck 🚨
Last 30d: 66-58-4 (+1.8u)
BUF +5.5 (Live)-110
0.14u
Live alert
The Propfessor
The Propfessor
Last 30d: 14-16-0 (+1.5u)
S.Barkley o17.5 Longest Rush-108
0.75u
Mike McNamara
Mike McNamara
Last 30d: 75-78-1 (+3.3u)
BUF -3-120
0.36u
Jeremiah Rose
Jeremiah Rose
Last 30d: 48-42-0 (-3.0u)
Under 46-120
0.33u
Boomer’s Book
YBB SportsData
YBB SportsData
Last 30d: 0-0-0 (+0.0u)
Under 45-110
1u
Scott Rickenbach
Scott Rickenbach
Last 30d: 85-78-2 (-5.7u)
PHI +3-105
0.95u
Markus Markets
Markus Markets
Last 30d: 11-16-0 (-3.5u)
J.Allen 30+ Rushing Yards Yes-125
1u
Vegas Refund
Vegas Refund
Last 30d: 31-23-1 (+5.5u)
PHI +3-108
1u
Picks Office
Picks Office
Last 30d: 0-0-0 (+0.0u)
PHI +1.5-105
0.95u
Matt DiLeo
Matt DiLeo
Last 30d: 50-30-0 (+9.1u)
J.Hurts u189.5 Pass Yds-112
0.89u
YBK Picks.com
Last 30d: 38-28-0 (+18.0u)
BUF -3-105
2u
Allan Lem
Allan Lem
Last 30d: 40-28-1 (+3.6u)
K.Shakir u4.5 Recs-134
0.67u
Odds aren’t great but projecting this closer to 3.5
Mjaybrod
Mjaybrod
Last 30d: 53-64-2 (-7.4u)
PHI +2.5-102
1.47u
Should have known this was coming
OldSchool0909
Last 30d: 98-126-1 (-28.3u)
PHI +1.5-110
0.91u
New Owner
New Owner
Last 30d: 0-0-0 (+0.0u)
D.Smith o45.5 Rec Yds-110
$110.00
Kendra Middleton
Kendra Middleton
Last 30d: 10-15-0 (-1.9u)
BUF -1.5-105
1u
Gilles Gallant
Gilles Gallant
Last 30d: 20-34-0 (+9.5u)
J.Hurts Anytime TD Scorer Yes+145
0.7u
J.Hurts 2+ TDs Yes+1100
0.3u
Sandy Plashkes
Sandy Plashkes
Last 30d: 88-71-1 (+41.0u)
D.Smith o48.5 Rec Yds-112
1.12u
Gilles Gallant
Gilles Gallant
Last 30d: 20-34-0 (+9.5u)
J.Allen o0.5 Int+130
0.5u
NFL INT PICKS - W17
DeadPresPicks
DeadPresPicks
Last 30d: 0-1-0 (-1.0u)
BUF -115
0.65u
Cam Is Money
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
J.Cook o11.5 Rec Yds-115
1u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 23-68-1 (-0.0u)
J.Hurts Anytime TD Scorer Yes+145
0.5u
T.Johnson Anytime TD Scorer Yes+550
0.5u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 41-63-0 (+6.0u)
BUF -1.5-110
1u
@sundaysixpack @Stuckey2 https://myaction.app/9Vu6o9PHlZb
Sunday Six Pack
Sunday Six Pack
Last 30d: 0-0-0 (+0.0u)
BUF -1.5-110
1.1u
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 0-0-0 (+0.0u)
Under 43.5-105
0.1u
🚀Become a Pro Bettor in 7-Days! (Link in Bio)
Mike McNamara
Mike McNamara
Last 30d: 75-78-1 (+3.3u)
BUF -148
0.6u

Eagles vs. Bills Previews & Analysis

  • Eagles vs. Bills: Prime Spot to Back Josh Allen article feature image

    Eagles vs. Bills: Prime Spot to Back Josh Allen

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    Dec 28, 2025 UTC
  • Action Analytics: 6 Data-Driven NFL Picks & Parlays for Week 17 article feature image

    Action Analytics: 6 Data-Driven NFL Picks & Parlays for Week 17

    Action Predictive Analytics•
    Dec 28, 2025 UTC
  • Koerner & Raybon's Week 17 Spreads & Totals article feature image

    Koerner & Raybon's Week 17 Spreads & Totals

    Chris Raybon•
    Dec 28, 2025 UTC
  • Koerner's Week 17 Pick'em & Confidence Rankings article feature image

    Koerner's Week 17 Pick'em & Confidence Rankings

    Sean Koerner•
    Dec 28, 2025 UTC
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Eagles vs. Bills Props

Prop Projections

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Prop Odds Comparison

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Eagles vs. Bills Public Betting Percentages

Away Logo

Eagles

Public

57%

Bets%

43%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Bills
3-02-01-03-0N/A
Eagles
0-30-10-20-3N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Bills
2-11-11-02-1N/A
Eagles
2-11-01-12-1N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Bills
3-0N/AN/A3-0N/A
Eagles
2-1N/AN/A2-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 21st@CLEW 23-20-10.5 LO 41.5BUF -582
Dec 14th@NEW 35-31-2.5 WO 49.5BUF -142
Dec 7thCINW 39-34-6 LO 54.5BUF -285
Nov 30th@PITW 26-7-3 WU 44.5BUF -173
Nov 21st@HOUL 19-23-4.5 LU 44HOU -240

Bills vs. Eagles Injury Updates

Bills Injuries

    Eagles Injuries

    • Dallas Goedert
      TE

      Goedert is out with knee

      Out

    • Hollywood Brown
      WR

      Brown is questionable with ankle

      Questionable

    • Eli Stowers
      TE

      Stowers is out with hamstring

      Out

    Team Stats
    190
    Total Yards
    331
    54
    Total Plays
    73
    3.5
    Yards Per Play
    4.5
    110
    YDS
    262
    13/27
    Comps/Atts
    23/35
    3.857
    YPA
    5.275
    1/0
    TDs/INTs
    0/0
    1/2
    Sacks/Yards
    5/51
    82
    Rush Yards
    120
    26
    Attempts
    33
    3.154
    YPC
    3.636
    0
    TDs
    2

    Turnovers

    0
    Fumbles Lost
    1
    0
    Interceptions
    0

    Efficiency

    1/2 50%
    Redzone
    2/3 66.67%
    3/13 0%
    3rd Down
    6/15 0%
    0/0 0%
    4th Down
    2/3 0%

    First Downs

    11
    Total
    20
    6
    Pass
    11
    4
    Rush
    7
    1
    Penalty
    2
    3/36
    Penalties/Yards
    4/40
    24:45
    Possession
    35:15

    Eagles vs. Bills Odds Comparison

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    Eagles at Bills Team Totals

    MatchupOverUnder
    Eagles
    2-1
    N/A
    N/A
    Bills
    3-0
    N/A
    N/A