New year, same old story for the San Francisco 49ers.
San Francisco has been crushed by the injury bug already this season, which might make it difficult to lock in an early 49ers vs. Rams prediction for Thursday Night Football's spread.
Quarterback Brock Purdy is dealing with a toe injury and, because of the quick turnaround from Sunday to Thursday Night Football, is questionable to play against Los Angeles.
Los Angeles is a 7-point spread favorite against San Francisco according to live NFL odds, and despite the Niners' injury woes, bettors are relatively split on how to approach this number.
However, what's really interesting is larger bettors don't seem all that worried and are still confidently pounding one side of the 49ers vs. Rams spread.
Here's what I mean.
49ers vs. Rams Prediction for Thursday's Spread
*Odds as of Wednesday afternoon
Fifty-five percent of spread tickets are laying the points with the Rams as of the time of writing.
