To help you make 2025 NFL Week 1 pick'em picks, I've ranked straight-up (SU) and against-the-spread (ATS) options by confidence below.
These rankings are based on my power ratings, which help power our NFL PRO Projections. They account for various factors, such as injuries and travel. These rankings will be updated again before Sunday's Week 1 games kick off — be sure to bookmark this story and check it again, especially since I’ll be able to better grasp what spreads I like.
Follow me in the Action App for notifications when I do lock in my betting picks.
