Astros vs. Guardians Odds & Betting Predictions - April 20, 2026

Astros at Guardians

10:10 pm • CLEG

Houston Astros

@

Cleveland Guardians

pitcher		team	era	w-l
S.Cecconi			0.00	0-0
C.Gordon			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Astros 8-13	N/A	N/A	N/A
Guardians 11-10	N/A	N/A	N/A

location pin

Monday 10:10 p.m.

April 20, 2026

Progressive FieldCleveland

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39°Fahrenheit

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0%Rain

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5Wind

No props found

MLB Public Betting

Guardians are 2-3 in their last 5 games.
Guardians are 2-3 in their last 5 games against the spread
Guardians are 6-7 in their road games against the spread
The totals have gone OVER in 3 of Guardians' last 5 games
The totals have gone OVER in 3 of Guardians' 8 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	12-9	6-2	6-7	4-3	8-6
Astros	8-13	6-5	2-8	4-9	4-3

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	10-11	3-5	7-6	3-4	7-7
Astros	13-7-1	7-4	6-3-1	7-6	5-1-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	11-10	5-3	6-7	4-3	7-7
Astros	8-13	7-4	1-9	5-8	3-4

date	opponent	score	spread	over/under	moneyline
Apr 17th	BAL	L 4-6	-1.5 L	O 8	BAL -141
Apr 16th	BAL	W 4-2	-1.5 W	U 8	CLE -136
Apr 15th	@STL	L 3-5	-	U 9	STL -112
Apr 14th	@STL	L 5-6	-1.5 L	O 9	STL -120
Apr 13th	@STL	W 9-3	-1.5 W	O 8	CLE -120

Zach Dezenzo
LF
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MatchupOverUnder
Astros 8-13	N/A	N/A
Guardians 11-10	N/A	N/A