Cardinals vs. Cubs Odds & Betting Predictions - September 28, 2025

Cardinals at Cubs

7:20 pm • FDSMW

St. Louis Cardinals

0

0 - 2

Chicago Cubs

2

pitcher		team	era	w-l
J.Assad			3.65	4-1
K.Leahy			3.07	4-2

MatchupOpenSpreadTotalMoneyline
Cardinals 4-2	+1.5	+1.5-181	o7-118	+126
Cubs 3-3	u8.5	-1.5+144	u7-102	-155

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Sunday 7:20 p.m.

September 28, 2025

Wrigley FieldChicago

Cardinals vs Cubs: Who To Back in Toss-up Season Ender
Nick Martin•
Sep 28, 2025 UTC

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MLB Public Betting

Cubs are 3-2 in their last 5 games.
Cubs are 3-2 in their last 5 games against the spread
The totals have gone OVER in 2 of Cubs' last 5 games
The totals have gone OVER in 3 of Cubs' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	3-3	3-3	N/A	3-3	N/A
Cardinals	4-2	4-2	N/A	N/A	4-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	3-3	3-3	N/A	3-3	N/A
Cardinals	3-3	3-3	N/A	N/A	3-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	3-3	3-3	N/A	3-3	N/A
Cardinals	4-2	4-2	N/A	N/A	4-2

date	opponent	score	spread	over/under	moneyline
Sep 27th	STL	W 7-3	-1.5 W	O 9.5	CHC -178
Sep 26th	STL	W 12-1	-1.5 W	O 9	CHC -184
Sep 25th	NYM	L 5-8	+1.5 L	O 7.5	NYM -103
Sep 25th	NYM	W 10-3	+1.5 W	O 7.5	CHC -118
Sep 23rd	NYM	L 7-9	+1.5 L	O 7.5	NYM +100

Tyler Austin
1B
Austin is out with knee
Out
Justin Steele
SP
Steele is out with elbow
Out
Jordan Wicks
SP
Wicks is out with arm
Out
Seiya Suzuki
RF
Suzuki is out with knee
Out

Lars Nootbaar
LF
Nootbaar is out with heel
Out
Hunter Dobbins
SP
Dobbins is out with knee
Out

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PITCHER		PC	IP	K	ER
RK.Leahy, P		39	3	1	0
LJ.King, P		18	1.2	2	1
RM.Svanson, P		17	1.1	2	0
RR.Fernandez, P		18	1	2	0

HITTERS	H-AB	R	HR	RBI
1J.Fermin, 2B	0-2	0	0	0
2I.Herrera, DH	0-3	0	0	0
3N.Gorman, 3B	0-3	0	0	0
4T.Saggese, SS	1-3	0	0	0
5J.Walker, RF	0-3	0	0	0
6J.Crooks, C	1-3	0	0	0
7Y.Pozo, 1B	0-3	0	0	0
8V.Scott, CF	2-3	0	0	0
9N.Church, LF	0-2	0	0	0

PITCHER		PC	IP	K	ER
RJ.Assad, P		79	5.1	6	0
RM.Soroka, P		7	0.2	0	0
LJ.Wicks, P		17	1.1	1	0

HITTERS	H-AB	R	HR	RBI
1M.Busch, 1B	0-3	0	0	0
1R.McGuire, C	-
2N.Hoerner, 2B	1-3	0	0	0
2N.Hoerner, SS	1-3	0	0	0
3I.Happ, LF	0-2	0	0	0
3K.Alcantara, LF	1-1	1	0	0
4K.Tucker, DH	0-3	0	0	0
5S.Suzuki, RF	1-3	1	1	1
6M.Ballesteros, C	1-3	0	0	1
6M.Ballesteros, 1B	1-3	0	0	1
7P.Crow-Armstrong, CF	1-3	0	0	0
8D.Swanson, SS	0-1	0	0	0
8J.Turner, PH	0-1	0	0	0
8J.Turner, 3B	0-1	0	0	0
9W.Castro, 3B	0-2	0	0	0
9W.Castro, 2B	0-2	0	0	0

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MatchupOverUnder
Cardinals 4-2	N/A	N/A
Cubs 3-3	N/A	N/A