Cardinals vs. Cubs Odds & Betting Predictions - September 27, 2025

Cardinals at Cubs

6:20 pm • FDSMW

St. Louis Cardinals

3

3 - 7

Chicago Cubs

7

pitcher		team	era	w-l
J.Taillon			3.68	11-7
M.McGreevy			4.42	8-4

MatchupOpenSpreadTotalMoneyline
Cardinals 4-2	+1.5	+1.5-133	o9.5-107	+150
Cubs 3-3	u9	-1.5+110	u9.5-113	-178

location pin

Saturday 6:20 p.m.

September 27, 2025

Wrigley FieldChicago

Under 9.5-110

0.55u

Under 9.5-115

0.58u

Bet to 9 (-105)

No props found

MLB Public Betting

Cubs are 3-2 in their last 5 games.
Cubs are 3-2 in their last 5 games against the spread
The totals have gone OVER in 2 of Cubs' last 5 games
The totals have gone OVER in 3 of Cubs' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	3-3	3-3	N/A	3-3	N/A
Cardinals	4-2	4-2	N/A	N/A	4-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	3-3	3-3	N/A	3-3	N/A
Cardinals	3-3	3-3	N/A	N/A	3-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	3-3	3-3	N/A	3-3	N/A
Cardinals	4-2	4-2	N/A	N/A	4-2

date	opponent	score	spread	over/under	moneyline
Sep 26th	STL	W 12-1	-1.5 W	O 9	CHC -184
Sep 25th	NYM	L 5-8	+1.5 L	O 7.5	NYM -103
Sep 25th	NYM	W 10-3	+1.5 W	O 7.5	CHC -118
Sep 23rd	NYM	L 7-9	+1.5 L	O 7.5	NYM +100
Sep 21st	@CIN	L 0-1	+1.5 W	U 9	CIN +105

Tyler Austin
1B
Austin is out with knee
Out
Justin Steele
SP
Steele is out with elbow
Out
Jordan Wicks
SP
Wicks is out with arm
Out
Seiya Suzuki
RF
Suzuki is out with knee
Out

Lars Nootbaar
LF
Nootbaar is out with heel
Out
Hunter Dobbins
SP
Dobbins is out with knee
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RM.McGreevy, P		88	4.2	3	3
LJ.King, P		6	0.1	0	0
RR.Fernandez, P		19	1	2	2
RM.Svanson, P		14	1	2	0
RJ.Alcala, P		28	1	1	2

HITTERS	H-AB	R	HR	RBI
1L.Nootbaar, LF	0-3	0	0	0
2I.Herrera, DH	1-4	0	0	0
3A.Burleson, 1B	0-4	0	0	0
4N.Arenado, 3B	2-4	1	1	1
5N.Gorman, 2B	1-4	0	0	0
6T.Saggese, SS	0-4	0	0	0
7J.Crooks, C	2-4	1	0	0
8J.Walker, RF	1-2	1	1	2
9V.Scott, CF	0-2	0	0	0
9J.Fermin, PH	0-1	0	0	0
9N.Church, CF	0-1	0	0	0

PITCHER		PC	IP	K	ER
RJ.Taillon, P		83	6	8	1
LC.Thielbar, P		15	1	2	2
LD.Pomeranz, P		11	1	2	0
RB.Keller, P		26	1	1	0

HITTERS	H-AB	R	HR	RBI
1M.Busch, 1B	4-4	2	2	4
2N.Hoerner, 2B	0-5	0	0	0
3I.Happ, LF	1-4	0	0	0
4K.Tucker, DH	0-4	0	0	0
5S.Suzuki, RF	1-2	2	1	1
6C.Kelly, C	1-4	0	0	0
7P.Crow-Armstrong, CF	2-4	1	1	2
8D.Swanson, SS	1-3	0	0	0
9M.Shaw, 3B	0-3	2	0	0

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MatchupOverUnder
Cardinals 4-2	N/A	N/A
Cubs 3-3	N/A	N/A