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Cubs vs. Guardians Odds & Betting Predictions - April 4, 2026

Cubs at Guardians

11:15 pm • FOX

Chicago Cubs

3-4
0
0 - 0

Cleveland Guardians

5-3
0
Starting Pitchers
pitcherteameraw-l
Slade Cecconi logoS.CecconiCleveland Guardians logo12.460-1
Shota Imanaga logoS.ImanagaChicago Cubs logo7.200-1

Cubs at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
3-4
-1.5
-1.5+129
o8-105
-133
Guardians
5-3
u8
+1.5-155
u8-113
+112
location pinSaturday 11:15 p.m.
April 04, 2026
Progressive FieldCleveland

Cubs vs. Guardians Previews & Analysis

  • Neiffer's Saturday Home Run Picks article feature image

    Neiffer's Saturday Home Run Picks

    Grant Neiffer•
    Apr 4, 2026 UTC
  • Trollo's Shota Prop for Cubs-Guards article feature image

    Trollo's Shota Prop for Cubs-Guards

    Matt Trollo•
    Apr 4, 2026 UTC
  • Saturday's Opening Pitch article feature image

    Saturday's Opening Pitch

    Matt Trollo•
    Apr 4, 2026 UTC
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Prop Odds Comparison

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No props found

Line Movement Tracker

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Cubs vs. Guardians Public Betting Percentages

Away Logo

Cubs

Public

Home Logo

Guardians

71%

Bets%

29%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Guardians are 3-2 in their last 5 games.
  • Guardians are 3-2 in their last 5 games against the spread
  • Guardians are 4-3 in their road games against the spread
  • The totals have gone OVER in 1 of Guardians' last 5 games
  • The totals have gone OVER in 0 of Guardians' 1 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians		5-31-04-31-04-3
Cubs		3-43-30-13-30-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians		3-50-13-40-13-4
Cubs		3-43-30-13-30-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians		5-31-04-31-04-3
Cubs		3-43-30-13-30-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 3rdCHCW 4-1-U 7.5CLE -115
Apr 2nd@LADW 4-1+1.5 WU 8CLE +245
Apr 1st@LADL 1-4---
Mar 31st@LADW 4-2+1.5 WU 8.5CLE +158
Mar 29th@SEAL 0-8+1.5 LO 7.5SEA +122

Guardians vs. Cubs Injury Updates

Guardians Injuries

    Cubs Injuries

    • Tyler Austin
      1B

      Austin is out with knee

      Out

    • Justin Steele
      SP

      Steele is out with elbow

      Out

    • Jordan Wicks
      SP

      Wicks is out with arm

      Out

    • Seiya Suzuki
      RF

      Suzuki is out with knee

      Out

    See more MLB Injuries Right Arrow
    Cubs vs. Guardians Box Score
    Cubs Player Stats
    Projected
    PITCHERPCIPKER
    HITTERSH-ABRHRRBI
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Slade Cecconi logoRS.Cecconi, P
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, CF-
    Angel Martinez logo2A.Martinez, LF-
    Jose Ramirez logo3J.Ramirez, 3B-
    David Fry logo4D.Fry, DH-
    Chase DeLauter logo5C.DeLauter, RF-
    Rhys Hoskins logo6R.Hoskins, 1B-
    Gabriel Arias logo7G.Arias, SS-
    Austin Hedges logo8A.Hedges, C-
    Brayan Rocchio logo9B.Rocchio, 2B-

    Cubs vs. Guardians Odds Comparison

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    Cubs at Guardians Team Totals

    MatchupOverUnder
    Cubs
    3-4
    N/A
    N/A
    Guardians
    5-3
    N/A
    N/A