Guardians vs. Astros Odds & Betting Predictions - June 21, 2026
Guardians at Astros
6:10 pm • CLEGStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.35 | 5-6 | ||
![]() | 5.07 | 4-7 |
Guardians at Astros Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Guardians 64-66 | +1.5 | +1.5-188 | o8.5-105 | +112 |
Astros 65-65 | u8.5 | -1.5+157 | u8.5-111 | -133 |

Daikin ParkHouston
Guardians vs. Astros Expert Picks
Player Prop Savant
Last 30d: 84-73-1 (+10.9u)
HOU o0.5+160
1.6u
HOU o4.5+100
1u

Sean Zerillo
Last 30d: 105-135-7 (-8.5u)
Under 8.5-104
0.5u
Bet to -115
Allan Lem
Last 30d: 24-15-1 (+2.3u)
Under 8.5-104
0.5u
Need a Kai-Wei Teng masterclass 🙏
Wags Wins
Last 30d: 203-179-4 (+7.4u)
Under 8.5+100
1.5u
RoyalsProps
Last 30d: 0-0-0 (+0.0u)
J.Altuve o1.5 Hits + Runs + RBIs+104
1u
Ryan Minion
Last 30d: 232-285-12 (-51.5u)
C.Walker o1.5 Hits + Runs + RBIs-120
$1.20
#ACTION ✍️✍️ #MLBLeadoff
💰🦡 Jake
Last 30d: 34-66-2 (-13.1u)
CLE +116
1u
Frank Ammirante
Last 30d: 417-439-13 (-14.4u)
T.Bazzana o0.5 HR+741
0.1u
T.Bazzana o1.5 Total Bases+141
0.71u
Guardians vs. Astros Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Astros Public Betting Percentages
Betting Trends
- Astros are 2-3 in their last 5 games.
- Astros are 1-4 in their last 5 games against the spread
- Astros are 32-31 in their road games against the spread
- The totals have gone OVER in 1 of Astros' last 5 games
- The totals have gone OVER in 36 of Astros' 67 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Astros Box Score
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 79 | 6 | 1 | 2 | |
![]() | 9 | 1 | 1 | 0 | |
![]() | 14 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
Astros Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 83 | 6 | 4 | 1 | |
![]() | 21 | 1 | 3 | 0 | |
![]() | 11 | 1 | 1 | 0 | |
![]() | 9 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-2 | 2 | 1 | 1 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 3-4 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
Guardians vs. Astros Odds Comparison
Could not load odds
Guardians at Astros Team Totals
MatchupOverUnder | ||
|---|---|---|
Guardians 64-66 | N/A | N/A |
Astros 65-65 | N/A | N/A |































