The Clemson Tigers take on the Georgia Tech Yellow Jackets in Atlanta, Georgia, on Saturday, Sept. 13. Kickoff is set for 12 p.m. ET on ESPN.
Clemson is favored by 3.5 points on the spread with a moneyline of -162. The Yellow Jackets, meanwhile, come in at +136 to pull off the upset. The total is set at 53.5 points.
Here’s my Clemson vs. Georgia Tech prediction and college football picks for Saturday, September 13.


Clemson vs Georgia Tech Prediction
- Clemson vs. Georgia Tech Pick: Over 54 or Better · Bryant Wesco Anytime TD (-110)
My Georgia Tech vs. Clemson best bet is on both teams to go over the total and Tigers wide receiver to score a touchdown. Find the best line available on our live NCAAF odds page.
Clemson vs Georgia Tech Odds
Clemson Odds | ||
---|---|---|
Spread | Total | Moneyline |
-3.5 -108 | 54.5 -110o / -110u | -162 |
Georgia Tech Odds | ||
---|---|---|
Spread | Total | Moneyline |
+3.5 -112 | 54.5 -110o / -110u | +136 |
- Clemson vs Georgia Tech Spread: Clemson -3.5, Georgia Tech +3.5
- Clemson vs Georgia Tech Over/Under: 54.5 Points
- Clemson vs Georgia Tech Moneyline: Clemson -162, Georgia Tech +136


Clemson vs Georgia Tech College Football Betting Preview

Clemson Tigers Betting Preview: Injuries Abounding
The Clemson offense has not hit its stride during the 2025 season in two games against LSU and Troy.
The source of the stalling offense can be traced to a ground attack missing running back Jay Haynes due to injury.
Clemson averaged 2.9 yards per carry against LSU, having half of its 18 attempts stuffed in the opening loss. Those numbers slightly increased against Troy, as the Tigers averaged just 4.3 yards per carry while producing only a single explosive run.
Freshman Gideon Davidson has just two attempts on the season, while converted wide receiver Adam Randall averages just 2.5 yards after first contact.
The loss of slot receiver Antonio Williams has kept quarterback Cade Klubnik's numbers down. The senior has produced a turnover-worthy play in both games against Troy and LSU.
Sophomore wideout Bryant Wesco has served as the home-run hitter for Klubnik in the passing game. Meanwhile, head coach Dabo Swinney has called Williams day-to-day with a hamstring injury.
Defensive coordinator Tom Allen was hired to create a run defense that has slacked in previous seasons.
With a Line Yards rank in the top 35 and a current Stuff Rate rank of 10th, the defense has shored up methodical drives from opponents.
The bad news is a lack of pass rush, which sits in the bottom 10 of all teams, per PFF.
Allen has carried over his pension for creating Havoc with his defenses, as Clemson sits top-10 thanks to pass breakups and tackles for loss that sit in the double digits.

Georgia Tech Yellow Jackets Betting Preview: Offense Keeps Clicking
Georgia Tech's combination of quarterback Haynes King and running back Jamal Haynes continues to torment opposing defenses.
Offensive coordinator Buster Faulkner has already produced top-25 numbers in Success Rate, Havoc Allowed and Line Yards through two games against Gardner-Webb and Colorado.
King didn't play against Gardner-Webb with a lower-body injury, but Georgia Tech is one of the rare offenses with minimal drop-off at quarterback thanks to experienced backup Aaron Philo.
New defensive coordinator Blake Gideon has had success through two games in limiting the rush and preventing opponents from executing in scoring opportunities. The Yellow Jackets sit top-25 in both Finishing Drives allowed and rush efficiency but have lacked a secondary that can cause disruption.
In fact, Georgia Tech grades out at 113th in coverage, per PFF, as a trio of cornerbacks leads the team with just a single pass breakup per player.

Clemson vs Georgia Tech Pick, Betting Analysis
From a historical perspective, Georgia Tech has had issues in this series, going without a win since 2014. Tech received good news from a health perspective, as King returned to the practice field as a full participant.
As for the biggest spark on the Clemson offense, Williams is still considered day-to-day leading up to this game.
Considering the poor play by the Yellow Jackets' secondary, there could be plenty of explosives on the outside for Clemson's targets. Georgia Tech cornerbacks Zachary Tobe and Jy Gilmore have already surrendered a touchdown this season, so an anytime touchdown for Bryant Wesco Jr. — who scored twice against Troy last week — should be considered.
The lack of a running game on the Clemson side, combined with the Yellow Jackets' ability to defend the rush, could force Klubnik to take to the skies.
Georgia Tech's offense will look to take advantage of a Clemson run defense that ranks 67th in Success Rate.
The Tigers have been mauled by outside zone read so far this season, producing a low 40% Success Rate. Georgia Tech has been excellent in a number of run concepts this season, including a high 57% Success Rate on outside zone.
Both teams will have avenues to push the ball into scoring territory, while special teams may help with field position. Clemson checks in at 133rd in the latest SP+ special teams rankings, a benefit for Georgia Tech in numerous categories.
Pick: Over 54 or Better · Bryant Wesco Anytime TD (-110)