College Football Betting Predictions, Picks: 4 Top Saturday Bets Include Michigan State vs. Purdue, Penn State vs. Maryland

College Football Betting Predictions, Picks: 4 Top Saturday Bets Include Michigan State vs. Purdue, Penn State vs. Maryland article feature image
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Photo by Adam Ruff/Icon Sportswire via Getty Images. Pictured: Michigan State Spartans quarterback Payton Thorne

  • Saturday's top college football betting predictions and picks include Wake Forest vs. UNC, Michigan State vs. Purdue and Penn State vs. Maryland.
  • In addition, the lower-profile Coastal Carolina vs. Georgia Southern matchup is also fitting a very profitable college football betting system.
  • Using our college football PRO betting tools, we detail Saturday's four smartest college football predictions and picks.

The College Football Playoff rankings are here, meaning we’ve officially reached Overreaction SZN.

Michigan State! Cincinnati! Oklahoma! Everybody seems to have an opinion, but you know what they say about opinions…

While there’s still plenty of season left and these rankings will change, the CFP rankings do matter, and they have an influence on the betting market as well.

Casual bettors will see these rankings and make decisions that are impacted by the numbers beside these teams.

This creates value for those willing to take unpopular sides and totals, and that’s exactly where savvy bettors are quietly piling on ahead of Saturday’s Week 10 matchups.

College Football Betting Predictions

*Odds and betting data as of Friday afternoon

Wake Forest vs. UNC Betting Prediction

12 p.m. ET | ABC

Right off the bat we get a fun one in the ACC with Wake Forest – ninth in the CFP rankings – taking on North Carolina.