The Colorado Buffaloes take on the Kansas State Wildcats in Manhattan, Kansas. Kickoff is set for 12:00 p.m. EST on Fox Sports 1.
Kansas State is favored by 16.5 points on the spread with a moneyline of -900. The total is set at 49.5 points.
Here’s my Colorado vs. Kansas State prediction and college football picks for Saturday, November 29, 2025.
Colorado vs Kansas State Prediction
- Colorado vs. Kansas State Pick: Kansas State 1H TT Over 17.5 (+110, DraftKings)
My Kansas State vs. Colorado best bet is on over K-State's first-half team total. Find the best line available on our live NCAAF odds page.
Colorado vs Kansas State Odds
| Colorado Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+16.5 -102 | 49.5 -115o / -105u | +600 |
| K State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-16.5 -118 | 49.5 -115o / -105u | -900 |
- Colorado vs Kansas State point spread: Kansas State -16.5 (-118), Colorado +17.5 (-102)
- Colorado vs Kansas State over/under: 49.5 (-115o / -105u)
- Colorado vs Kansas State moneyline: Colorado +600, Kansas State -900
Colorado vs Kansas State Preview
Colorado Buffaloes Betting Preview
Only one game remains on the slate for the 3-8 Colorado Buffaloes.
It's been a nightmare finish to the season as Colorado dropped its last four games, three of which came by 25-plus points.
To wrap up the season, the Buffs travel to Manhattan, a notoriously tricky place to play, to face Kansas State.
Week 14 presents the final opportunity for outbound transfers to bolster their resume.
Quarterback Julian Lewis may not play in this game. The large spread shift away suggests he's more likely to sit than not. Playing in the finale burns his redshirt opportunity, and the offense hasn't been very different under his command.
Deion Sanders could opt to go with Kaidon Salter, who would be playing in his final collegiate game, or Ryan Staub, who started a game early on.
Either way, Kansas State should see increased opportunities with the football on Saturday.
This year, Colorado hasn't been able to lean on its defense like last season. The Buffs rank 106th nationally in points per drive allowed and 97th in quality drive percentage allowed.
It doesn't get crushed up front; instead, it gets crushed around the perimeter.
Colorado's defense doesn't tackle well, especially in space. When games get out of hand, it's because opponents are getting to the edge and breaking a tackle or two.
K-State especially likes to attack the perimeter with Avery Johnson.
There's not much left to say about Colorado at this point in the season.
How much longer will Sanders stay in Boulder, given his increasing absences due to health scares, and with none of his sons left in the program? Is he at a point to grind out another decade here with a real rebuild, especially when the transfer portal starts to dry up?
Speculation, for sure, but reasonable speculation with a program without a real, defined future.
Kansas State Wildcats Betting Preview
Betting on or against the Kansas State Wildcats is like playing roulette.
Throw your chips down on black, and K-State comes to a 14-6 finish against Oklahoma State. Bet on red, and the Wildcats take Utah to the brink in a wild 52-47 shootout.
Bet evens and the Wildcats lose outright to Army, while odds produce a 41-28 resounding win over TCU.
In short, random and frustrating.
That 50/50 split on Kansas State even carries over to its 5-6 record.
The mixed bag really starts with quarterback Avery Johnson.
He never really cashed the check written, at least not this season. Johnson has 18 turnover-worthy throws, per PFF, but just six interceptions to show – mind you, six loud interceptions in critical moments, severe missed throws, or a combination of both.
He also hasn't been as dynamic running the ball this year as he was last year. Compared to last year, on almost the same number of attempts, Johnson has 136 fewer rushing yards, 13 fewer 10-plus yard runs, and less than half the missed tackles forced.
Some of it can be chalked up to scheme, but Johnson regressed individually.
A couple of absences on offense don't help.
Running back Dylan Edwards, who transferred here this offseason, decided to leave the program after spending most of the year on the injury report. Without Edwards, the down-to-down success dropped, as Kansas State ranks 114th in Rushing Success Rate.
Last week, the second-leading receiver, tight end Garrett Oakley, went down with an injury and did not return.
What's made this team look a little worse is a defense that, at best, is perfectly average and, at worst, gets obliterated.
K-State's last three losses featured opponents hanging 35, 43, and 51 points. It has an uncanny knack for giving up way too many big plays (watch the fourth quarter of the Utah game).
On a down-to-down basis, the defense is quite good. But on 3rd-and-7, opponents find 40 and the end zone.
When the defense does buckle down, you get results like a 42-17 win over rival Kansas and a 41-28 win over TCU that was far less close than it appeared.
Kansas State's ceiling is about as high as anyone's in the Big 12. But its floor is as low as anyone's, too.
For proof of both, look at its last two games.
Colorado vs Kansas State Pick, Betting Analysis
Kansas State is a 17.5-point favorite in the game, way up from an opening of -11.5. The over/under ticked down a touch from 51.5 to 50.5.
K-State needs the win Saturday to clinch a bowl game after it came up just short in that wild Utah game. Especially in the final couple of weeks of the season, I like to back teams that need the win to keep playing against opponents with nothing left to lose.
The point spread is long past bettable for Kansas State.
Instead, I'm looking to a familiar bet: fading Colorado's first-half defense and effort.
Kansas State's offense lives and dies by big plays (as does its defense), and Colorado has a big-time tackling problem.
The other half comes in the quarterback uncertainty for Colorado. Irregular tempo on offense could lead to turnovers and more opportunities for the opposing offense.
Colorado is also a team that recognizes when it's beaten.
Keep the Buffs around – like Arizona State did in the first quarter last week or like West Virginia did two games ago – and Colorado threatens.
But the minute that score gets the slightest bit lopsided, this team packs it in, especially on defense. Look to the Utah and Arizona games for proof of that snowballing.
Kansas State's offense is capable of breaking the defense early. It's also a goal-oriented team at home against a team with little to play for other than personal gain (the transfer portal).
I'll take the Wildcats' first-half team total and look for them to blow this game open early.
Pick: Kansas State 1H TT Over 17.5 (+110, DraftKings)
