The Notre Dame Fighting Irish take on the Arkansas Razorbacks in Fayetteville, Arkansas, on Saturday, Sept. 24. Kickoff is set for 12 p.m. ET on ABC.
Notre Dame is favored by 4 points on the spread with a moneyline of -180. Arkansas, meanwhile, is a +4 underdog and comes in at +150 on the moneyline to pull off the upset. The over/under sits at 64.5 points.
Here’s my Notre Dame vs. Arkansas prediction and college football picks for Saturday, September 27.
Notre Dame vs Arkansas Prediction
- Notre Dame vs. Arkansas Pick: Arkansas +4 · Taylen Green Over 51 Rushing Yards · Mike Washington Jr. Over 60 Rushing Yards · Jadarian Price Over 70 Rushing Yards · Jadarian Price Anytime TD -135
My Arkansas vs. Notre Dame best bets are on the Razorbacks to cover the spread and more player props. Find the best line available on our live NCAAF odds page.
Notre Dame vs Arkansas Odds
| Notre Dame Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4 -110 | 64.5 -110o / -110u | -180 |
| Arkansas Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4 -110 | 64.5 -110o / -110u | +150 |
- Notre Dame vs Arkansas Spread: Notre Dame -4, Arkansas +4
- Notre Dame vs Arkansas Over/Under: 64.5 Points
- Notre Dame vs Arkansas Moneyline: Notre Dame -180, Arkansas +150
Notre Dame vs Arkansas College Football Betting Preview
Notre Dame Fighting Irish Betting Preview: Back to Basics
With two losses to start the season, Notre Dame will more than likely need to win out to return to the College Football Playoff.
Both sides of the ball have taken a step back from last year's national title run, but in particular, the offense has struggled to create a clean box score. The offensive line has allowed 15 tackles for loss while also grading 122nd in PFF pass blocking.
True freshman quarterback CJ Carr has dodged 23 pressures in just 83 dropbacks.
On the other side of the ball, Notre Dame returned to basics against Purdue, allowing running backs Jeremiyah Love and Jadarian Price to combine for 231 rushing yards and five touchdowns.
On the other side of the ball, the change from Al Golden to Chris Ash at defensive coordinator has been one of the biggest drop-offs in college football. A once swarming secondary now grades 115th in coverage and 118th in allowing pass explosives.
The Havoc department has been lifeless as well, as the Irish rank second-to-last in tackles for loss, forced fumbles and pass breakups.
The defensive front has struggled to defend any run concept that's not inside zone, particularly against teams that run man-blocking schemes.
Arkansas Razorbacks Betting Preview: Pittman on Hot Seat
The buzzards are swirling around the coaching staff of the Arkansas Razorbacks, as head coach Sam Pittman has acknowledged outside noise that's affecting the locker room atmosphere.
A one-score loss at Ole Miss could be forgiven, but a late turnover on the final drive of the Memphis game sank the Hogs to a 2-2 record on the season.
Pittman acknowledged that the defense's effort was subpar, as the Razorbacks missed 12 tackles and had no presence at the line of scrimmage.
Defensive coordinator Travis Williams has a significant issue with Arkansas' defensive line, which ranks 122nd in opponent rush efficiency and ground explosives allowed.
The nickel package has had no luck defending inside zone read concepts, achieving a Success Rate under 40%.
The great news for Arkansas is that it has an elite offense led by coordinator and potential interim head coach Bobby Petrino.
Quarterback Taylen Green leads a unit that's top-20 in nearly every category, from Success Rate to EPA. The sixth-year Boise State transfer leads the team in rushing yards, deriving 234 yards from designed calls and 145 yards off scrambles.
Running back Mike Washington Jr. has been the bell cow in man and zone read rushing attempts, while wide receiver O'Mega Blake checks in at 2.6 yards per route run on 35 targets from Green.
Notre Dame vs Arkansas Pick, Betting Analysis
In 2025, Notre Dame and Arkansas have both demonstrated their inability to defend against the rush. A look at the run concepts suggests that any player carrying the ball could have a big day.
Arkansas runs man-blocking schemes for Washington and Green more than any other concept, an area in which Notre Dame has a 35% Success Rate. Washington and Green have eclipsed 60 rushing yards in every Razorback game and have become an add as rushing props.
Conversely, Notre Dame runs a balance of inside and outside zone read concepts. The Arkansas defensive line has been putrid against inside zone, creating an opportunity for investment on Irish running backs.
Both Price and Love get zone read rushing attempts, with Price being the more explosive of the two so far. Both players should be added as rushing prop over investments, with a look at Price for an anytime touchdown.
Action Network's betting power ratings project this game at Notre Dame -4 with a total of 63.5, providing no value to the current market.
Arkansas has the better offense and special teams to this point in the season. The Hogs could be overlooked by the Irish after their loss to Memphis, so Fayetteville is expected to draw one of the largest crowds in Donald W. Reynolds Stadium history.
Any Arkansas pregame wager would require a live hedge on the Irish as these offenses march up and down the field on the ground.
Pick: Arkansas +4 · Taylen Green Over 51 Rushing Yards · Mike Washington Jr. Over 60 Rushing Yards · Jadarian Price Over 70 Rushing Yards · Jadarian Price Anytime TD (-135)
