The San Jose State Spartans take on the Stanford Cardinal in Stanford, CA. Kickoff is set for 7:30 p.m. ET on ACC Network.
Stanford is favored by -2.5 points on the spread with a moneyline of -135. The total is set at 49.5 points.
Here’s my San Jose State vs. Stanford predictions and college football picks for Saturday, September 27, 2025.
San Jose St vs Stanford Prediction
- San Jose State vs. Stanford Pick: San Jose State +2.5
My Stanford vs. San Jose State best bet is on the Spartans spread. Find the best line available on our live NCAAF odds page.
San Jose State vs Stanford Odds
| San Jose State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+2.5 -108 | 49.5 -115o / -105u | +115 |
| Stanford Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-2.5 -112 | 49.5 -115o / -105u | -135 |
- San Jose Stte vs Stanford point spread: Stanford -2.5
- San Jose Statea vs Stanford over/under: 49.5 points
- San Jose State vs Stanford moneyline: San Jose State +115, Stanford -135
San Jose State vs Stanford Pick, Betting Analysis
In the preseason, Stanford (1-3) was projected to finish in last place in the ACC, according to the conference's official media vote. The Cardinal have matched those expectations thus far, although their schedule hasn't exactly been a walk in the park.
Stanford's three losses have come on the road, including one in Hawaii and in a cross-country trip to Virginia.
Meanwhile, the Spartans are 1-2, with one of those defeats coming to Texas in Austin. San Jose State is coming off a 31-28 victory against Idaho last week.
In a game between two under .500 squads, the play is on the Spartans spread. Our very own Evan Abrams has a system — "Early Road Redemption" — that's backing this +2.5 bet.
In fact, the system has a nice 9.4% return on investment (ROI) since its inception in 2005.
"Early Road Redemption" is a system that identifies value on visiting teams in the opening stretch of the season after they've underperformed against the spread in their previous outing.
That matches for this game because even though San Jose State beat Idaho, it failed to cover the 13.5-point spread.
The market often punishes these teams too heavily for a single early loss, creating inflated lines in the next matchup — which is happening here for the Spartans.
By narrowing the spread range between modest underdogs and double digit spots, the system captures situations where the road team is competitive but overlooked.
These games are played in manageable weather conditions and typically fall within lower scoring totals, which reduce volatility and keep contests closer than expected.
When teams in their first eight games seek redemption on the road after a poor showing against the spread, they frequently outperform expectations, making this a profitable angle.
If sprinkling on the moneyline creates better value, then that isn't frowned upon based on Evan Abrams' "Short Road Dogs" system.
Pick: San Jose State +2.5
