Roma vs Lazio Odds & Live Scores - September 21, 2025 | The Action Network

Roma at Lazio

10:30 am

Roma

23-11-4

1

1 - 0

Lazio

14-12-12

0

MatchupOpenSpreadTotalMoneyline
Roma 23-11-4	-1	-0.5+160	o2.5+125	N/A
Lazio 14-12-12	u2.5	+0.5-235	u2.5-164	N/A

location pin

Sunday 10:30 a.m.

September 21, 2025

Stadio OlimpicoRome

ROM PK-122

1u

Serie A Public Betting

Lazio are 3-1 in their last 5 games.
Lazio are 3-2 in their last 5 games against the spread
Lazio are 8-11 in their road games against the spread
The totals have gone OVER in 4 of Lazio' last 5 games
The totals have gone OVER in 10 of Lazio' 19 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Lazio	16-22	8-11	8-11	10-10	6-12
Roma	4-2-1	1-2-1	3-0	4-2-1	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Lazio	15-23	10-9	5-14	11-9	4-14
Roma	4-3	2-2	2-1	4-3	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Lazio	14-12	8-5-6	6-7-6	10-1-9	4-11-3
Roma	5-2	2-2	3-0	5-2	N/A

date	opponent	score	spread	over/under	moneyline
Sep 14th	@SAS	L 0-1	-0.5 L	U 2.5	SAS -112
Aug 31st	VER	W 4-0	-1 W	O 2.5	-
Aug 24th	@COM	L 0-2	+0.5 L	U 2.5	COM +210
May 25th	LEC	L 0-1	-1.5 L	U 2.5	LEC -227
May 18th	@INT	L 2-2	+1 W	O 2.5	INT +392

Samuel Gigot
DEF
Ankle/Foot Injury
Out
Gustav Isaksen
F
Isaksen is injured with groin
Out Indefinitely

Angelino
DEF
Thigh Muscle Strain
Out Indefinitely
Wesley Franca
DEF
Franca is out with groin
Out

See more SERIEA Injuries

Roma

Lazio

22

Fouls

14

11

Shots

11

6

Corners

3

4

Offsides

0

0

Red Cards

2

1

Yellow Cards

1

6

Shots On Goal

3

51%

Possession Time

49%

Roma

Goalkeeping

Lazio

Could not load odds

See more Serie A Odds

MatchupOverUnder
Roma 23-11-4	N/A	N/A
Lazio 14-12-12	N/A	N/A