| Ander Herrera | MID | Out indefinitely | Hamstring | Hamstring | Apr 11 |
| Asier Villalibre | F | Out indefinitely | Hamstring | Hamstring | May 2 |
| Inaki Williams | F | Out indefinitely | Hamstring | Hamstring | Feb 13 |
| Alex Berenguer | MID | Out | Suspended | Suspended | Feb 27 |
| Yuri Berchiche | DEF | Out | Suspended | Suspended | Feb 11 |
| Cesar Azpilicueta | DEF | Out | Head Injury | Head Injury | Apr 11 |
| Memphis Depay | F | Out indefinitely | Hamstring | Hamstring | Apr 11 |
| Thomas Lemar | MID | Out indefinitely | Knee Injury | Knee Injury | Feb 27 |
| Rodrigo De Paul | MID | Out indefinitely | Hamstring | Hamstring | Mar 14 |
| Jose Maria Gimenez | DEF | Out indefinitely | Knock | Knock | Jan 30 |
| Koke | MID | Out indefinitely | Hamstring | Hamstring | Nov 9 |
| Alvaro Morata | F | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Reinildo Mandava | DEF | Out indefinitely | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Apr 11 |
| Axel Witsel | MID | Out indefinitely | Knock | Knock | May 2 |
| Nahuel Molina | DEF | Out | Suspended | Suspended | Sep 3 |
| Pablo Barrios Rivas | MID | Out indefinitely | None | Barrios Rivas is injured | Dec 2 |
| Ante Budimir | F | Out indefinitely | Pubalgia | Pubalgia | Oct 25 |
| Unai Garcia | DEF | Out indefinitely | None | Garcia is injured | Mar 29 |
| Lucas Torro | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | May 23 |
| Sergio Herrera | GK | Out indefinitely | Knee Injury | Knee Injury | Nov 9 |
| Aitor Fernandez | GK | Out | Virus | Virus | May 27 |
| Aimar Oroz | MID | Out indefinitely | None | Oroz is injured | Apr 14 |
| Kike Barja | MID | Out indefinitely | None | Barja is injured | Mar 8 |
| A. Nyom | DEF | Out | Suspended | Suspended | Feb 13 |
| Ezequiel Muñoz | DEF | Out | Hamstring | Hamstring | Feb 12 |
| Eraso | MID | Out | Suspended | Suspended | May 16 |
| Víctor David Díaz Miguel | DEF | Out | Suspended | Suspended | Jan 8 |
| Unai Bustinza Martínez | DEF | Out | Suspended | Suspended | Oct 1 |
| Rubén Pérez | MID | Out | Suspended | Suspended | Jan 26 |
| M. Dos Santos | DEF | Out indefinitely | Hamstring | Hamstring | Feb 24 |
| Marc Navarro | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Jan 3 |
| Nabil El Zhar | MID | Out indefinitely | Knock | Knock | Apr 27 |
| R. Rosales | DEF | Out | Suspended | Suspended | Dec 8 |
| Recio | MID | Out | Suspended | Suspended | May 1 |
| Rubén Pardo | MID | Out | Suspended | Suspended | Nov 5 |
| Enric Franquesa | DEF | Out | Virus | Virus | May 28 |
| Xavier Quintillà Guasch | DEF | Out | Suspended | Suspended | Feb 2 |
| Fede Vico | MID | Out | Suspended | Suspended | Apr 1 |
| Jorge Sáenz | DEF | Out indefinitely | Shoulder Injury | Shoulder Injury | Jan 18 |
| Luis Perea | MID | Out | Suspended | Suspended | Feb 7 |
| Yacine Qasmi | A | Out | Suspended | Suspended | May 29 |
| Y. Neyou | MID | Out | Suspended | Suspended | Feb 25 |
| Luis Hernandez | DEF | Out indefinitely | None | Hernandez is injured | Jan 18 |
| Jimenez Juanmi | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jan 30 |
| Jorge Mere | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Dec 14 |
| Fede San Emeterio | MID | Out indefinitely | None | San Emeterio is injured | Jan 18 |
| Jose Mari | MID | Out indefinitely | None | Mari is injured | Apr 12 |
| Andoni Gorosabel | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Feb 20 |
| Alex Sola | DEF | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Ander Guevara | MID | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Aleksandar Sedlar | DEF | Out indefinitely | None | Sedlar is injured | Nov 11 |
| Marcos Alonso | DEF | Out indefinitely | Knock | Knock | Sep 5 |
| Ilkay Gundogan | MID | Out | Groin Strain | Groin Strain | Feb 21 |
| Oriol Romeu | MID | Out | Suspended | Suspended | Dec 14 |
| Robert Lewandowski | F | Out indefinitely | Hamstring | Hamstring | Mar 14 |
| Marc-Andre Ter Stegen | GK | Out indefinitely | Illness | Illness | May 10 |
| Joao Cancelo | DEF | Out indefinitely | Virus | Virus | Aug 8 |
| Raphinha | F | Out | Suspended | Suspended | Apr 1 |
| Joao Felix | F | Doubtful | None | Felix is doubtful | Feb 10 |
| Pedri | MID | Out indefinitely | Hamstring | Hamstring | Apr 11 |
| Borja Mayoral | F | Out indefinitely | None | Mayoral is injured | Mar 8 |
| Mauro Arambarri | MID | Out indefinitely | None | Arambarri is injured | Jan 31 |
| David Soria | GK | Out | Broken Finger | Broken Finger | Sep 4 |
| Nemanja Maksimovic | MID | Out indefinitely | Knock | Knock | Oct 29 |
| Domingos Duarte | DEF | Out indefinitely | None | Duarte is injured | Mar 29 |
| Omar Alderete | DEF | Out | Suspended | Suspended | Mar 19 |
| Juan Iglesias | DEF | Out indefinitely | Knock | Knock | Feb 22 |
| Ilaix Moriba | MID | Out indefinitely | Hamstring | Hamstring | Dec 28 |
| Mubarak Wakaso | MID | Out | Suspended | Suspended | Jan 18 |
| Daley Blind | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jun 15 |
| Yangel Herrera | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 4 |
| Ricard Artero Ruiz | MID | Out indefinitely | None | Artero Ruiz is injured | Mar 8 |
| Juanpe | DEF | Doubtful | None | Juanpe is doubtful | Apr 19 |
| Casals Joel Roca | F | Out indefinitely | None | Roca is injured | Mar 8 |
| Cristhian Stuani | F | Out indefinitely | None | Stuani is injured | Apr 19 |
| Lucas Boye | F | Out | Suspended | Suspended | Apr 1 |
| Raul Torrente | DEF | Doubtful | None | Torrente is doubtful | Apr 18 |
| Rúben Vezo | DEF | Out | Suspended | Suspended | Oct 31 |
| Bruno | DEF | Out | Suspended | Suspended | Dec 18 |
| Iborra | MID | Out | Suspended | Suspended | Jan 22 |
| Samuel García Sánchez | MID | Out | Knee Injury | Knee Injury | Jan 8 |
| Wesley Moraes | A | Out indefinitely | Knee Injury | Knee Injury | Apr 25 |
| E. Bardhi | MID | Out indefinitely | Hamstring | Hamstring | Nov 10 |
| Marcelo Josemir Saracchi Pintos | DEF | Out | Suspended | Suspended | Mar 25 |
| Miramón | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Dec 21 |
| Joni Montiel | MID | Out | Suspended | Suspended | Jan 14 |
| N. Vukčević | MID | Out indefinitely | Sprained Ankle | Sprained Ankle | Oct 25 |
| Toño | DEF | Out | Suspended | Suspended | Apr 30 |
| M. Peybernes | DEF | Out | Suspended | Suspended | Feb 19 |
| Juanfran | DEF | Out indefinitely | Hamstring | Hamstring | Nov 26 |
| Weligton Róbson Pena de Oliveira | DEF | Out indefinitely | Knee Injury | Knee Injury | Jun 9 |
| Juan Carlos Pérez López | DEF | Out | Suspended | Suspended | Jan 5 |
| Miguel Torres Gómez | DEF | Out | Hamstring | Hamstring | May 24 |
| Sérgio Paulo Barbosa Valente | MID | Out indefinitely | Toe Injury | Toe Injury | May 22 |
| Keko | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | May 5 |
| Zdravko Kuzmanović | MID | Out indefinitely | Pubalgia | Pubalgia | Jun 12 |
| Jozabed | MID | Out | Suspended | Suspended | Jan 22 |
| Pablo Hervías | MID | Out indefinitely | Cartilage Knee Injury | Cartilage Knee Injury | Apr 6 |
| Adrián | A | Out indefinitely | Knock | Knock | Jun 15 |
| Brandon Thomas Llamas | A | Out | Suspended | Suspended | Jan 3 |
| C. Gönen | GK | Out indefinitely | Shoulder Injury | Shoulder Injury | Jun 12 |
| L. Agbenyenu | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Jul 17 |
| Joaquín Muñoz | A | Out | Suspended | Suspended | Mar 27 |
| P. Chavarría | A | Out indefinitely | Knock | Knock | Sep 29 |
| E. Burgos | DEF | Out | Suspended | Suspended | Feb 20 |
| M. Benkhemassa | MID | Out | Suspended | Suspended | Jan 26 |
| Caye Quintana | A | Out | Suspended | Suspended | Dec 5 |
| Jonás Ramalho | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Nov 22 |
| Genaro Rodríguez | MID | Out | Suspended | Suspended | Jan 15 |
| Jasper Cillessen | GK | Out indefinitely | Hamstring | Hamstring | Apr 4 |
| Javi Manquillo | DEF | Out indefinitely | None | Manquillo is injured | Jan 22 |
| Jonathan Bamba | F | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Jan 31 |
| Franco Cervi | F | Out | Suspended | Suspended | Oct 2 |
| Renato Tapia | MID | Out | Suspended | Suspended | Mar 11 |
| Joseph Aidoo | DEF | Out indefinitely | None | Aidoo is injured | Oct 20 |
| Luca De la Torre | MID | Out | Hamstring | Hamstring | Nov 22 |
| Manu Sanchez | MID | Out indefinitely | Hamstring | Hamstring | May 12 |
| Unai Nunez | DEF | Out | Suspended | Suspended | Feb 12 |
| M. Koné | A | Out | Suspended | Suspended | Jan 12 |
| Raúl Carnero | DEF | Out | Suspended | Suspended | Mar 19 |
| Fernando Navarro i Corbacho | DEF | Out | Suspended | Suspended | Apr 1 |
| Rober | DEF | Out indefinitely | Knock | Knock | Nov 29 |
| Omar Mascarell | MID | Out | Suspended | Suspended | Feb 15 |
| Matija Nastasic | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Jun 14 |
| Sergi Darder | MID | Out | Virus | Virus | Jan 17 |
| Cyle Larin | F | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Mar 8 |
| Pablo Maffeo | DEF | Out | Suspended | Suspended | Nov 9 |
| Nemanja Radonjic | F | Out indefinitely | None | Radonjic is injured | Jul 27 |
| Martin Valjent | DEF | Out indefinitely | Back Injury | Back Injury | Apr 11 |
| Predrag Rajkovic | GK | Out indefinitely | Medical Condition | Medical Condition | Nov 30 |
| Vedat Muriqi | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Nov 28 |
| Antonio Sanchez | MID | Out | Shoulder Injury | Shoulder Injury | Sep 13 |
| Ivan Balliu | DEF | Out | Suspended | Suspended | Oct 17 |
| Falcao | F | Out indefinitely | Knock | Knock | Nov 7 |
| Oscar Trejo | F | Out | Calf Muscle Strain | Calf Muscle Strain | Jun 5 |
| Unai Lopez | MID | Out indefinitely | Hamstring | Hamstring | Apr 4 |
| Bebe | MID | Out | Suspended | Suspended | Feb 4 |
| Aridane | DEF | Out indefinitely | None | Aridane is injured | Apr 19 |
| Alvaro Garcia | MID | Doubtful | None | Garcia is doubtful | Apr 12 |
| Oscar Valentin | MID | Out indefinitely | Rib Injury | Rib Injury | Feb 7 |
| Diego Mendez | MID | Out indefinitely | None | Mendez is injured | Jan 20 |
| Alfonso Espino | DEF | Out | Suspended | Suspended | Feb 19 |
| Hector Bellerin | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Oct 29 |
| Claudio Bravo | GK | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Dec 7 |
| Youssouf Sabaly | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Apr 11 |
| Nabil Fekir | F | Out indefinitely | ACL Knee Ligament Injury | ACL Knee Ligament Injury | Apr 11 |
| Pablo Fornals | MID | Out indefinitely | None | Fornals is injured | Jan 20 |
| German Pezzella | DEF | Out | Suspended | Suspended | Apr 3 |
| Rui Silva | GK | Out indefinitely | None | Silva is injured | Nov 11 |
| Ayoze Perez | F | Out indefinitely | Illness | Illness | Dec 27 |
| Ezequiel Avila | F | Out indefinitely | None | Avila is injured | Apr 19 |
| Juan Miranda | DEF | Out indefinitely | Knock | Knock | Apr 11 |
| Ez Abde | MID | Out | Suspended | Suspended | Feb 12 |
| Abner Vinicius | DEF | Out indefinitely | None | Vinicius is injured | Feb 17 |
| Thibaut Courtois | GK | Out indefinitely | Hamstring | Hamstring | Feb 20 |
| David Alaba | DEF | Out indefinitely | Hamstring | Hamstring | Apr 11 |
| Antonio Rudiger | DEF | Out indefinitely | Hamstring | Hamstring | Dec 7 |
| Kepa Arrizabalaga | GK | Out | Ankle/Foot Injury | Ankle/Foot Injury | Dec 25 |
| Dani Ceballos | MID | Out indefinitely | Hamstring | Hamstring | Oct 31 |
| Dani Carvajal | DEF | Out indefinitely | Hamstring | Hamstring | Jan 30 |
| Luka Modric | MID | Doubtful | None | Modric is doubtful | Dec 1 |
| Ferland Mendy | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 11 |
| Andriy Lunin | GK | Out | Virus | Virus | Dec 29 |
| Aurelien Tchouameni | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Feb 2 |
| Jude Bellingham | MID | Out indefinitely | Knock | Knock | Dec 6 |
| Eduardo Camavinga | MID | Out indefinitely | None | Camavinga is injured | Nov 25 |
| Mikel Merino | MID | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Umar Sadiq | F | Out indefinitely | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Apr 11 |
| Carlos Fernandez | F | Out indefinitely | None | Fernandez is injured | Jan 19 |
| Andre Silva | F | Out | Back Injury | Back Injury | Feb 26 |
| Hamari Traore | DEF | Out | Calf Muscle Strain | Calf Muscle Strain | Mar 11 |
| Martin Merquelanz | MID | Out indefinitely | None | Merquelanz is injured | Oct 2 |
| Aihen Munoz | DEF | Out indefinitely | None | Munoz is injured | Jan 26 |
| Ander Barrenetxea | F | Doubtful | None | Barrenetxea is doubtful | Mar 8 |
| Y. Muto | A | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Apr 26 |
| Matheus Pereira | MID | Out | Suspended | Suspended | Oct 30 |
| Etxeita | DEF | Out | Suspended | Suspended | Apr 23 |
| Anaitz Arbilla Zabala | DEF | Out | Suspended | Suspended | Mar 13 |
| Iván Ramis Barrios | DEF | Out indefinitely | Knee Injury | Knee Injury | Jul 24 |
| Francisco Manuel Rico Castro | MID | Out indefinitely | Knee Injury | Knee Injury | Jun 30 |
| Imanol Sarriegui Isasa | MID | Out | Hand Injury | Hand Injury | Mar 7 |
| Roberto Antonio Correa Silva | DEF | Out | Suspended | Suspended | Jan 8 |
| Paulo Oliveira | DEF | Out indefinitely | Hamstring | Hamstring | Dec 29 |
| G. Blanco | A | Out | Suspended | Suspended | Jan 10 |
| Javi Muñoz | MID | Out | Suspended | Suspended | Apr 1 |
| Enrique González Casín | A | Out indefinitely | Knock | Knock | Dec 23 |
| Peru Nolaskoain | DEF | Out | Suspended | Suspended | Jan 15 |
| Juan Berrocal | DEF | Out | Suspended | Suspended | Mar 7 |
| S. Okazaki | A | Out indefinitely | Hamstring | Hamstring | Nov 9 |
| Mikel Rico | MID | Out indefinitely | Virus | Virus | Nov 9 |
| Pablo Ínsua Blanco | DEF | Out | Suspended | Suspended | Apr 2 |
| Timor | MID | Out indefinitely | Knock | Knock | Dec 20 |
| Luisinho | DEF | Out indefinitely | Knee Injury | Knee Injury | May 22 |
| Juan Pablo Añor Acosta | MID | Out indefinitely | Hamstring | Hamstring | May 1 |
| Juan Pérez | GK | Out indefinitely | Arm/Elbow injury | Arm/Elbow injury | Dec 20 |
| Cristian Salvador | MID | Out | Suspended | Suspended | Jan 9 |
| Óscar Sielva | MID | Out | Suspended | Suspended | Feb 26 |
| Gerard Valentín | DEF | Out indefinitely | Hamstring | Hamstring | Dec 26 |
| Eugeni Valderrama | MID | Out indefinitely | Hamstring | Hamstring | May 22 |
| K. Nwakali | MID | Out indefinitely | Knock | Knock | Oct 18 |
| Pedro López Muñoz | DEF | Out indefinitely | Hamstring | Hamstring | Nov 9 |
| Juan Carlos | | Out | Virus | Virus | Jan 31 |
| Pablo Martínez | MID | Out | Suspended | Suspended | Oct 31 |
| Jesus Navas | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Feb 16 |
| Erik Lamela | MID | Out | Suspended | Suspended | Sep 18 |
| Djibril Sow | MID | Out indefinitely | Knock | Knock | Jun 14 |
| Orjan Nyland | GK | Out indefinitely | Back Injury | Back Injury | Feb 14 |
| Dodi Lukebakio | F | Out indefinitely | Virus | Virus | Jan 17 |
| Lucas Ocampos | F | Out indefinitely | Knock | Knock | Dec 20 |
| Suso | F | Out indefinitely | Hamstring | Hamstring | Aug 27 |
| Mariano Diaz | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jan 13 |
| Rafa Mir | F | Out indefinitely | Knock | Knock | Apr 4 |
| Marcos Acuna | DEF | Out | Suspended | Suspended | Aug 27 |
| Lucien Agoume | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Jan 19 |
| Loic Bade | DEF | Out indefinitely | Hamstring | Hamstring | Feb 25 |
| Boubakary Soumare | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Feb 18 |
| Alejo Veliz | F | Out indefinitely | None | Veliz is injured | Feb 2 |
| Ibrahima Sow | F | Out indefinitely | None | Sow is injured | Apr 13 |
| Alejandro Bergantiños García | MID | Out | Suspended | Suspended | Mar 11 |
| Javi Fuego | MID | Out | Suspended | Suspended | Mar 26 |
| Álvaro Vázquez | A | Out | Shoulder Injury | Shoulder Injury | Sep 12 |
| Jony | MID | Out | Suspended | Suspended | Feb 12 |
| Pichu Cuéllar | GK | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Mar 1 |
| J. Babin | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Feb 25 |
| Fernando Amorebieta Mardaras | DEF | Out indefinitely | Knock | Knock | Apr 3 |
| Pedro Díaz Fanjul | MID | Out | Suspended | Suspended | May 10 |
| Juan Rodríguez Martínez | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | May 1 |
| Sergio Álvarez Díaz | MID | Out | Suspended | Suspended | Feb 12 |
| José Ángel Valdés Díaz | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Aug 24 |
| Jordi Calavera Espinach | DEF | Out indefinitely | Knock | Knock | Apr 22 |
| Pablo Pérez | MID | Out | Suspended | Suspended | May 7 |
| Molinero | DEF | Out | Suspended | Suspended | Jul 6 |
| Marc Valiente | DEF | Out | Suspended | Suspended | Nov 30 |
| J. Otero | A | Out | Suspended | Suspended | Dec 14 |
| Víctor Campuzano | A | Out indefinitely | Back Injury | Back Injury | Mar 1 |
| Vasyl Kravets | DEF | Out | Suspended | Suspended | Jan 23 |
| Fran Villalba | MID | Out | Suspended | Suspended | Apr 2 |
| José Marsà | DEF | Out | Suspended | Suspended | Apr 8 |
| Diego Marino | GK | Out | Suspended | Suspended | Feb 26 |
| Luis Suarez | F | Out | Suspended | Suspended | Apr 22 |
| Gonzalo Melero | MID | Suspended | None | Melero is suspended | Mar 29 |
| Marko Milovanovic | F | Out indefinitely | Pubalgia | Pubalgia | Oct 29 |
| Cesar Montes | DEF | Out indefinitely | Head Injury | Head Injury | Feb 27 |
| Aleksandar Radovanovic | DEF | Out indefinitely | None | Radovanovic is injured | Apr 13 |
| Daley Sinkgraven | DEF | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Julian Araujo | DEF | Out indefinitely | None | Araujo is injured | Mar 29 |
| Saul Coco | DEF | Suspended | None | Coco is suspended | Apr 19 |
| Marvin Park | MID | Suspended | None | Park is suspended | Apr 19 |
| Mouctar Diakhaby | DEF | Out indefinitely | None | Diakhaby is injured | Mar 8 |
| Dimitri Foulquier | DEF | Out indefinitely | Hamstring | Hamstring | Jan 20 |
| Jose Gaya | DEF | Out indefinitely | None | Gaya is injured | Mar 29 |
| Selim Amallah | MID | Out indefinitely | Hamstring | Hamstring | Apr 4 |
| Thierry Correia | DEF | Out indefinitely | Hamstring | Hamstring | Feb 27 |
| Hugo Guillamon | DEF | Out | Suspended | Suspended | Feb 11 |
| Roman Yaremchuk | F | Out indefinitely | None | Yaremchuk is injured | Apr 14 |
| Francis Coquelin | MID | Out indefinitely | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Apr 11 |
| Alberto Moreno | DEF | Out | Suspended | Suspended | Feb 18 |
| Eric Bailly | DEF | Out | Suspended | Suspended | Feb 13 |
| Etienne Capoue | MID | Out indefinitely | Knock | Knock | Apr 11 |
| Pepe Reina | GK | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Oct 10 |
| Raul Albiol | DEF | Out indefinitely | Hamstring | Hamstring | Jan 30 |
| Denis Suarez | MID | Out indefinitely | None | Suarez is injured | Dec 8 |
| Manu Trigueros | MID | Out | Suspended | Suspended | Feb 27 |
| Goncalo Guedes | MID | Out | Knock | Knock | Apr 21 |
| Juan Foyth | DEF | Out indefinitely | Knee Injury | Knee Injury | Nov 7 |
| Alexander Sorloth | F | Out indefinitely | Hamstring | Hamstring | Oct 18 |