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Astros vs. Reds Odds & Betting Predictions - May 10, 2026

Astros at Reds

5:40 pm • SCHN

Houston Astros

16-24
0
0 - 0

Cincinnati Reds

21-19
0

Astros at Reds Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
16-24
+1.5
-1.5+154
o9.5-109
-103
Reds
21-19
u9
+1.5-188
u9.5-110
-118
location pinSunday 5:40 p.m.
May 10, 2026
Great American Ball ParkCincinnati
Astros vs. Reds Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 177-118-4 (+57.3u)
CIN o4.5+100
1u
Picks Office
Picks Office
Last 30d: 180-171-10 (-2.0u)
HOU +105
1u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy Houston is priced like the ugly road team, but Abbott's 5.13 ERA and 1.64 WHIP are the real problem in this matchup. He has walked 19 and allowed 5 HR in 40.1 innings, which gives the Astros' top bats a direct path to traffic and damage. Bolton has risk, but 14 K and only 1 HR allowed in 11.2 innings makes +105 playable.
Over 9-115
1u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy Both starters bring traffic into this game, with Andrew Abbott at a 5.13 ERA and Cody Bolton at 4.63. Abbott has allowed 19 walks and 5 homers across 40.1 innings, while Bolton is carrying a 1.8 WHIP. Weather is mild at 66 degrees with 3 mph wind out, so Great American is not working against runs.
Sean Zerillo
Sean Zerillo
Last 30d: 171-156-17 (+3.1u)
Over 9-114
0.57u
Bet to -120
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 247-313-16 (+6.1u)
Over 0.5 (1st Inn)+110
0.4u
#EV 3.53% Pinny -106
Frank Ammirante
Frank Ammirante
Last 30d: 317-317-9 (+13.8u)
E.De La Cruz o0.5 HR+320
0.1u

Astros vs. Reds Previews & Analysis

  • MLB Best Bets for Sunday article feature image

    MLB Best Bets for Sunday

    Action Network Staff•
    May 10, 2026 UTC
  • Minion's SGP Playbook for Astros-Reds article feature image

    Minion's SGP Playbook for Astros-Reds

    Ryan Minion•
    May 10, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Reds Public Betting Percentages

Away Logo

Astros

Public

Home Logo

Reds

56%

Bets%

44%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Reds are 1-4 in their last 5 games.
  • Reds are 3-2 in their last 5 games against the spread
  • Reds are 13-7 in their road games against the spread
  • The totals have gone OVER in 3 of Reds' last 5 games
  • The totals have gone OVER in 14 of Reds' 20 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Reds		24-1611-913-77-417-12
Astros		16-248-118-134-1112-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Reds		24-15-114-610-9-17-417-11-1
Astros		25-13-214-511-8-29-615-7-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Reds		21-1911-910-107-414-15
Astros		16-249-107-145-1011-13

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 9thHOUW 3-1-1.5 WU 8.5CIN -162
May 8thHOUL 0-10-1.5 LO 9HOU -131
May 7th@CHCL 3-8+1.5 LO 9-
May 6th@CHCL 6-7+1.5 WO 8CHC +145
May 5th@CHCL 2-3+1.5 WU 8CHC +138

Astros vs. Reds Injury Updates

Astros Injuries

    Reds Injuries

    • Hunter Greene
      SP

      Greene is out with elbow

      Out

    See more MLB Injuries Right Arrow
    Astros vs. Reds Box Score
    Astros Player Stats
    Projected
    PITCHERPCIPKER
    Kai-Wei Teng logoRK.Teng, P
    HITTERSH-ABRHRRBI
    Jose Altuve logo1J.Altuve, 2B0-1000
    Yordan Alvarez logo2Y.Alvarez, DH0-1000
    Isaac Paredes logo3I.Paredes, 3B1-1000
    Christian Walker logo4C.Walker, 1B-
    Cam Smith logo5C.Smith, RF-
    Brice Matthews logo6B.Matthews, CF-
    Zach Cole logo7Z.Cole, LF-
    Nick Allen logo8N.Allen, SS-
    Cesar Salazar logo9C.Salazar, C-
    Reds Player Stats
    Projected
    PITCHERPCIPKER
    Andrew Abbott logoLA.Abbott, P140.210
    HITTERSH-ABRHRRBI
    Will Benson logo1W.Benson, RF-
    Spencer Steer logo2S.Steer, 1B-
    Elly De La Cruz logo3E.De La Cruz, SS-
    Sal Stewart logo4S.Stewart, DH-
    JJ Bleday logo5J.Bleday, LF-
    Tyler Stephenson logo6T.Stephenson, C-
    Blake Dunn logo7B.Dunn, CF-
    Matt McLain logo8M.McLain, 2B-
    Ke'Bryan Hayes logo9K.Hayes, 3B-

    Astros vs. Reds Odds Comparison

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    Astros at Reds Team Totals

    MatchupOverUnder
    Astros
    16-24
    N/A
    N/A
    Reds
    21-19
    N/A
    N/A