Cardinals vs. Mariners Odds & Betting Predictions - September 10, 2025

Cardinals at Mariners

1:40 am • ROOT Sports NW

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St. Louis Cardinals

@

Seattle Mariners

pitcher		team	era	w-l
G.Kirby			0.00	0-0
M.Liberatore			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Cardinals 72-72	N/A	N/A	N/A
Mariners 75-68	N/A	N/A	N/A

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Wednesday 1:40 a.m.

September 10, 2025

T-Mobile ParkSeattle

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69°Fahrenheit

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MLB Public Betting

Mariners are 2-3 in their last 5 games.
Mariners are 2-3 in their last 5 games against the spread
Mariners are 28-47 in their road games against the spread
The totals have gone OVER in 4 of Mariners' last 5 games
The totals have gone OVER in 34 of Mariners' 68 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Mariners	57-86	29-39	28-47	33-64	23-20
Cardinals	72-72	37-38	35-34	25-40	46-32

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Mariners	77-60-6	34-29-5	43-31-1	48-43-6	27-16
Cardinals	72-65-7	37-35-3	35-30-4	32-28-5	39-37-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Mariners	75-68	41-27	34-41	52-45	21-22
Cardinals	72-72	41-34	31-38	33-32	38-40

date	opponent	score	spread	over/under	moneyline
Sep 7th	@ATL	W 18-2	-	-	-
Sep 6th	@ATL	W 10-2	+1.5 W	O 9	SEA +107
Sep 5th	@ATL	L 1-4	+1.5 L	U 7.5	ATL +107
Sep 3rd	@TB	L 4-9	-1.5 L	O 8.5	TB -130
Sep 2nd	@TB	L 5-6	-1.5 L	O 7.5	TB -120

Nolan Arenado
3B
Arenado is out with shoulder
Out
Brendan Donovan
2B
Donovan is out with groin
Out

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MatchupOverUnder
Cardinals 72-72	N/A	N/A
Mariners 75-68	N/A	N/A