Cardinals vs Pirates Odds: Moneyline, Over/Under, Props - September 22, 2026 | The Action Network

Cardinals at Pirates

10:40 pm • SportsNet PT

St. Louis Cardinals

@

Pittsburgh Pirates

pitcher		team	era	w-l
J.Jones			0.00	0-0
A.Pallante			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Cardinals 75-80	N/A	N/A	N/A
Pirates 78-77	N/A	N/A	N/A

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Tuesday 10:40 p.m.

September 22, 2026

PNC ParkPittsburgh

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61°Fahrenheit

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31%Rain

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11Wind

No props found

MLB Public Betting

Pirates are 3-2 in their last 5 games.
Pirates are 4-1 in their last 5 games against the spread
Pirates are 40-38 in their road games against the spread
The totals have gone OVER in 4 of Pirates' last 5 games
The totals have gone OVER in 47 of Pirates' 77 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	77-78	37-40	40-38	36-42	40-34
Cardinals	82-73	40-40	42-33	16-34	65-37

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	80-69-6	47-28-2	33-41-4	45-31-2	33-37-4
Cardinals	72-77-6	36-41-3	36-36-3	24-25-1	46-51-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	78-77	41-36	37-41	44-34	33-41
Cardinals	75-80	37-43	38-37	24-26	50-52

date	opponent	score	spread	over/under	moneyline
Sep 20th	KC	W 4-3	+1.5 W	U 8.5	PIT -120
Sep 19th	KC	W 6-5	+1.5 W	O 8	PIT -117
Sep 18th	KC	W 8-5	-1.5 W	O 8.5	PIT -187
Sep 17th	MIL	W 7-4	+1.5 W	O 8.5	PIT +117
Sep 16th	MIL	L 4-5	+1.5 W	O 7.5	MIL +111

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MatchupOverUnder
Cardinals 75-80	N/A	N/A
Pirates 78-77	N/A	N/A