Guardians vs. Red Sox Odds & Betting Predictions - September 1, 2025

Guardians at Red Sox

5:35 pm • CLEG
4 - 6
Starting Pitchers
pitcherteameraw-l
Brayan Bello logoB.BelloBoston Red Sox logo3.3511-9
Parker Messick logoP.MessickCleveland Guardians logo2.723-1

Guardians at Red Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
1-2
+1.5
+1.5-168
o8-116
+122
Red Sox
1-2
u8.5
-1.5+142
u8-106
-146
location pinMonday 5:35 p.m.
September 01, 2025
Fenway ParkBoston
Guardians vs. Red Sox Expert Picks
Austin Pendergrass
Austin Pendergrass
Last 30d: 33-42-0 (-9.9u)
BOS -132 (Live)
0.38u
Sir Lockselot
Sir Lockselot
Last 30d: 29-75-0 (-53.0u)
CLE +122
2u
📚Player Profit 🔑 Guardians ML +122 (Player Profit) 2u I’m backing the Guardians moneyline today at +122 because while the Red Sox are modest favorites, Cleveland has shown surprising resilience as a road underdog. They’ve won more than half their games when listed as underdogs (+122 or longer) and have gone 4–1 recently. These odds offer value—Boston’s ~59% win probability overlooks the Guardians’ ability to stay competitive and produce upsets, making the +122 line a smart value play. Code: airlocks for 10% off at playerprofit.com
The Propfessor
The Propfessor
Last 30d: 58-52-0 (+1.9u)
P.Messick o15.5 Outs-115
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 94-116-6 (-5.0u)
Under 8.5-120
0.5u
Austin Pendergrass
Austin Pendergrass
Last 30d: 33-42-0 (-9.9u)
Under 4.5 (F5)-122
0.5u
Player Prop Savant
Player Prop Savant
Last 30d: 50-49-0 (-6.0u)
B.Bello u2.5 Earned Runs-130
1.3u
Allan Lem
Allan Lem
Last 30d: 158-127-2 (+4.3u)
Under 8.5-105
0.53u
Sean Zerillo
Sean Zerillo
Last 30d: 81-71-1 (+6.1u)
CLE +135
0.5u
Bet to +125

Guardians vs. Red Sox Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Red Sox Public Betting Percentages

Away Logo

Guardians

Public

17%

Bets%

83%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Red Sox
87-7543-3844-3753-5034-23
Guardians
86-7639-4247-3433-3651-38

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Red Sox
76-82-433-45-343-37-150-50-326-30-1
Guardians
69-87-637-41-332-46-334-34-134-50-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Red Sox
89-7348-3341-4061-4228-29
Guardians
88-7445-3643-3844-2543-46

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 31stPITW 5-2-1.5 WU 8.5BOS -175
Aug 30thPITL 3-10-1.5 LO 9PIT -188
Aug 29thPITL 2-4+1.5 LU 8PIT -118
Aug 28th@BALW 3-2-1.5 LU 8BOS -204
Aug 27th@BALW 3-2-1.5 LU 9BOS -139

Guardians vs. Red Sox Injury Updates

Guardians Injuries

    Red Sox Injuries

    • Tanner Houck
      SP

      Houck is out with arm

      Out

    • Johan Oviedo
      SP

      Oviedo is questionable with elbow

      Questionable

    • Patrick Sandoval
      SP

      Sandoval is out with elbow

      Out

    • Kutter Crawford
      SP

      Crawford is out with knee

      Out

    • Jovani Moran
      RP

      Moran is out with arm

      Out

    Guardians vs. Red Sox Box Score
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Parker Messick logoLP.Messick, P823.223
    Matt Festa logoRM.Festa, P100.110
    Erik Sabrowski logoLE.Sabrowski, P220.112
    Jakob Junis logoRJ.Junis, P151.211
    Zak Kent logoRZ.Kent, P37210
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF3-5000
    Daniel Schneemann logo2D.Schneemann, 2B0-3000
    Jose Ramirez logo3J.Ramirez, 3B0-4000
    Kyle Manzardo logo4K.Manzardo, 1B1-4111
    Bo Naylor logo5B.Naylor, C1-3100
    Nolan Jones logo6N.Jones, CF1-4100
    George Valera logo7G.Valera, DH0-1100
    David Fry logo7D.Fry, PH0-2000
    David Fry logo7D.Fry, DH0-2000
    CJ Kayfus logo8C.Kayfus, RF1-2001
    Jhonkensy Noel logo8J.Noel, PH0-2000
    Jhonkensy Noel logo8J.Noel, RF0-2000
    Brayan Rocchio logo9B.Rocchio, SS1-4002
    Red Sox Player Stats
    Projected
    PITCHERPCIPKER
    Brayan Bello logoRB.Bello, P100543
    Justin Wilson logoLJ.Wilson, P6100
    Steven Matz logoLS.Matz, P231.211
    Greg Weissert logoRG.Weissert, P20.100
    Aroldis Chapman logoLA.Chapman, P5110
    HITTERSH-ABRHRRBI
    Roman Anthony logo1R.Anthony, RF2-5100
    Alex Bregman logo2A.Bregman, 3B1-5100
    Trevor Story logo3T.Story, SS3-4112
    Romy Gonzalez logo4R.Gonzalez, 2B2-5001
    Romy Gonzalez logo4R.Gonzalez, 1B2-5001
    Rob Refsnyder logo5R.Refsnyder, DH2-5100
    Nate Eaton logo6N.Eaton, LF2-3100
    Jarren Duran logo6J.Duran, PH0-1000
    Jarren Duran logo6J.Duran, LF0-1000
    Ceddanne Rafaela logo7C.Rafaela, CF0-3000
    Nathaniel Lowe logo8N.Lowe, 1B0-2000
    Carlos Narvaez logo8C.Narvaez, PH1-1002
    David Hamilton logo8D.Hamilton, PR0-0000
    David Hamilton logo8D.Hamilton, 2B0-0000
    Connor Wong logo9C.Wong, C1-2100

    Guardians vs. Red Sox Odds Comparison

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    Guardians at Red Sox Team Totals

    MatchupOverUnder
    Guardians
    1-2
    o3.5-120
    u3.5-108
    Red Sox
    1-2
    o4.5+112
    u4.5-143